Yazar "Işıkdağ, İlhan" için listeleme
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QSAR of smooth muscle relaxation by 2,5-substituted-benzimidazole derivatives
Quantitative structure-activity anlayses were carried out for in vitro relaxant actions of a series of 2,5-substituted-benzimidazoles in rat duodenal smooth muscle. Analyses of simple and multiple linear regression models ... -
Studies of the synthesis of some 4,5-di and 2,4,5-trisubstituted imidazole derivatives
Işıkdağ, İlhan; Uçucu, Ümit; Çakır, B. (1989)[No abstract available] -
Studies on the synthesis of some 2,4,5-trisubstituted imidazole derivatives
Işıkdağ, İlhan; Uçucu, Ümit; Gündoğdu, N. (1994)[No abstract available] -
Studies on the synthesis of some 2-(1',3'-benzodioxol-5'yl)-benzimidazole, benzothiazole and benzoxazole derivatives
Işıkdağ, İlhan; Uçucu, Ümit; Ersan, S. (1991)[No abstract available] -
The study on the synthesis and the effects on the intracellular calcium of some 9-substituted-phenanthrene derivatives.
Işıkdağ, İlhan; Meriç, Asiye; Gÿnes, S.; Seller, Zerrin (2004)Some 9-(substituted with heteroaryl)-phenanthrene compounds, polycyclic aromatic hydrocarbons (PAH), were obtained by two different methods. In the first method, 9-phenanthraldehyde was reacted with some dion compounds ... -
Syntheses and analgesic activities of some 2-substituted-4,5-diphenyl and 1,2-disubstituted-4,5-diphenyl imidazole derivatives
Işıkdağ, İlhan; Meriç, Asiye (1999)Some substituted imidazole compounds were synthesized and their analgesic activities were determined on the Swiss albino mice (25-35 g) of either sex. During the synthesis, 2-substituted-4,5-diphenyl imidazole compounds ... -
Syntheses and structure elucidation of some 1- and 2-(aryl) substituted 4,5-bis (4-methoxyphenyl) imidazole derivatives
Meriç, Asiye; Işıkdağ, İlhan (2000)Some 1- and 2-(aryl)substituted 4,5-bis (4-methoxyphenyl) imidazole compounds and 2-(aryl) substituted 4,5-bis (4-methoxyphenyl) imidazole compounds were obtained by reacting anisil with some aldehyde derivatives in the ... -
Synthesis and analgesic activities of 2-substituted-1H-phenantro [9,10- d] imidazoles
Işıkdağ, İlhan; Uçucu, Ümit; Özdemir, Ahmet; Meriç, Asiye; Öztürk, Yusuf; Aydın, Süleyman; Ergün, Bülent (1999)Some 2-substituted-1H-phenantro [9, 10-d] imidazole compounds were synthesized and their analgesic activities were determined on the Swiss albino mice (25-35 g) of either sex. In the synthesis, phenantrenequinone molecule ... -
Synthesis and analgesic activity of some 1-benzyl-2-substituted-4,5-diphenyl-1H-imidazole derivatives
Uçucu, Ümit; Karaburun, N. G.; Işıkdağ, İlhan (2001)In this study, derivatives of 1-benzyl-2-substituted-4,5-diphenyl-1H-imidazole were synthesized and their analgesic activity assayed in two tests. 1,2,4,5-Tetrasubstituted imidazole compounds were obtained by the treatment ... -
Synthesis and anticancer activity of some bisquinoxaline derivatives
Işıkdağ, İlhan; Özkay, Yusuf; İncesu, Zerrin (2011)Mevcut antikanser ajanlara karşı rezistans gelişimi, yeni antikanser ajanlar için bir araştırma alanı yaratmaktadır. Bununla birlikte, normal hücreler üzerinde etki göstermeden ya da en az etkiyle anormal hücrelerin ... -
Synthesis and anticancer activity of some bisquinoxaline derivatives [Bazi biskinoksalin türevlerinin sentezleri ve antikanser aktiviteleri]
Işıkdağ, İlhan; Özkay, Yusuf; Seller, Zerrin (2011)Resistance improvement against the existing anticancer agents creates a research area for new anticancer agents. Nevertheless, it is rather difficult to develop a new agent which can selectively inhibit the proliferation ... -
Synthesis and Antimicrobial Activity of Some Novel Benzimidazole Hydrazides
Özkay, Yusuf; Tunalı, Yağmur; Karaca, H.; Işıkdağ, İlhan (Asian Journal Of Chemistry, 2011)The present study was undertaken to synthesize some 4-(5,6-dichloro-1H-benzimidazole-2-yl)phenoxyacetic acid-4-substituted benzylidene hydrazide derivatives and investigate their possible antimicrobial activity. Chemical ... -
Synthesis and antitumor activity of some 6-chloro- and 6,7-dichloro-2,3-disubstituted-quinoxaline derivatives
Bu çalışmada, 6-kloro- ve 6,7-dikloro-2,3-disübstitüe-kinoksalin türevleri sentezlenerek, sitotoksisiteleri ve antitümör etkileri araştırıldı. 6-Kloro- ve 6,7-dikloro-2,3-disübstitüe-kinoksalin bileşikleri, uygun 1,2-dikarbonil ... -
Synthesis and effects on intracellular calcium of some 1,3-bis-(heteroaryl substituted)benzene derivatives
Meriç, Asiye; Seller, Zerrin; Işıkdağ, İlhan (2002)A series of 1,3-bis-(heteroaryl substituted)benzene derivatives was designed as promising molecules which might increase intracellular Ca2+ level in F2408 fibroblast-like cells by affecting the Ca2+ channels on plasma ... -
Synthesis and mutagenicity of 2-aryl-substitute (o-hydroxy-, m-bromo-, o-methoxy-, o-nitro-phenyl or 4-pyridyl) benzothiazole derivatives on Salmonella typhimurium and human lymphocytes exposed in vitro
Tüylü, Berrin Ayaz; Sivas, Hülya; Işıkdağ, İlhan (Springer, 2007)Derivatives of 2-aryl-substitute (o-hydroxy-, m-bromo-, o-methoxy-, o-nitro-phenyl or 4-pyridyl) benzothiazole were synthesized and tested for their mutagenicity in in vitro assays: (i) in the Ames test with Salmonella ... -
Synthesis of 2-substituted-N-[4-(1-methyl-4,5-diphenyl-1H-imidazole-2-yl) phenyl]acetamide derivatives and evaluation of their anticancer activity
Özkay, Yusuf; Işıkdağ, İlhan; Seller, Zerrin; Akalın Çiftçi, Gülsen (Elsevier France-Editions Scientifiques Medicales Elsevier, 2010)In the present study 18 novel imidazole-(benz)azole and imidazole-piperazine derivatives were synthesized in order to investigate their probable anticancer activity. The structures of the compounds were confirmed by IR, ... -
Synthesis of some 2-alkylaminomethyl-benzimidazole dihydrochloride derivatives and determination of their structures
Işıkdağ, İlhan; Öztürk, Yusuf (1990)[No abstract available] -
Synthesis of some 2-aryl-benzoxazole derivatives and investigation of their mutagenicity
Uçucu, Ümit; Işıkdağ, İlhan; Gündoğdu, N.; MerçangÖz, A. (1995)In this study, eight of 2-aryl-benzoxazole derivatives have been synthesized. The comprehensive studies have not been found about spectral analyses of these compounds in the literature. For this reason, melting points of ...