Yazar "Cantürk, Zerrin" için listeleme
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Inhibitory effects of secondary metabolites of halotolerant aspergillus terreus on angiogenesis
Dikmen, Miriş; Cantürk, Zerrin; Engür, Selin; Kaya, Tilki, E. (Scientific Publishers of India, 2017)Angiogenesis inhibitors have been currently developed which offer the hope of new treatment options such as diabetic retinopathy, psoriasis, rheumatoid arthritis and cancer. Fungi have been known (as) a wide useful source ... -
Inhibitory effects of secondary metabolites of halotolerant Aspergillus terreus on angiogenesis.
Dikmen, Miriş; Cantürk, Zerrin; Engür, Selin; Tilki, Kaya E. (Allied Acad, 2017)Angiogenesis inhibitors have been currently developed which offer the hope of new treatment options such as diabetic retinopathy, psoriasis, rheumatoid arthritis and cancer. Fungi have been known (as) a wide useful source ... -
The Investigation of Cytotoxic Effects of Boron Compounds on Healty Human Lymphocyte
Cantürk, Zerrin; Tunalı, Yağmur; gülbas, Zafer (Taylor & Francis Inc, 2008)… -
Investigation of the Apoptotic Effect of Curcumin in Human Leukemia HL-60 Cells by Using Flow Cytometry
Dikmen, Miriş; Cantürk, Zerrin; Öztürk, Yusuf; Tunalı, Yağmur (Mary Ann Liebert, Inc, 2010)Curcumin (diferuloylmethane), the major yellow pigment isolated from the turmeric (Curcuma longa), has received much attention due to several biological properties. Curcumin exhibits a variety of pharmacological effects ... -
A New phenoxido/trifluoroacetato bridged heterometallic Ni-2(II)-Cu-II derivative: Structure, EPR interpretation and DFT computation
Daş, Kuheli; Datta, Amitabha; Mendiratta, Shruti; Garribba, Eugenio; Frontera, Antonio; Cantürk, Zerrin (Elsevier Science BV, 2019)The trinuclear heterometallic Ni-2(II)-Cu-II complex, [Ni-2(L)(2)(CF3COO)(2)Cu] (1) is afforded incorporating a tetradentate Schiff base precursor, H2L [where H2L = N,N'-bis(salicylidene)-1,3-propanediamine]. In 1, the two ... -
New Procaspase Activating Compound (PAC-1) Like Molecules as Potent Antitumoral Agents Against Lung Cancer
Yurttaş, Leyla; Öztürk, Ömer; Cantürk, Zerrin (Bentham Science Publ LTD, 2019)Background: In this study, novel ortho-hydroxy N-acyl hydrazone moiety including compounds (3a-l) were designed, based on procaspase activating compound (PAC-1) which is a small molecule known with antitumor activity. The ... -
New Thiophene Bearing Dimethyl-5-Hydroxy Isophtalate Esters and Their Antimicrobial Activities
Ünver, Hakan; Cantürk, Zerrin (2018)Thiophene belongs to a class of heterocyclic compounds. In this study, three new dimethyl-5-hydroxy isophtalate derived thiophene esters were successfully synthesized and characterized by FT-IR, Elementel Analysis, 1H-NMR, ... -
Postbiyotik içeren el kremi formülasyonu geliştirilmesi ve karakterizasyonu
Cantürk, Zerrin (Anadolu Üniversitesi - Sağlık Bilimleri Enstitüsü, 2022)Bu tez çalışmasının amacı, postbiyotikli krem formülasyonunun geliştirilmesi, hazırlanması ve sistemin karakterizasyon çalışmalarının yapılmasıdır. Postbiyotikler sadece kolon sağlığı için değil, deri için de olumlu etkileri ... -
Synthesis and antimicrobial activity evaluation of new dithiocarbamate derivatives bearing thiazole/benzothiazole rings
Yurttaş, Leyla; Özkay, Yusuf; Duran, Murat; Turan, Gülhan; Özdemir, Ahmet; Cantürk, Zerrin; Kaplancıklı, Zafer Asım (Taylor & Francis LTD, 2016)The synthesis of 2-(substituted phenyl)-2-oxoethyl 4-(pyrimidin-2-yl)piperazin-1-carbodithiodate (A1-A24) derivatives and 2-(4-substituted thiazol-2-ylamino)-2-oxoethyl 4-(pyrimidin-2-yl)piperazin-1-carbodithiodate (B1-B14) ... -
Synthesis and Biological Evaluation of Some New Amide Moiety Bearing Quinoxaline Derivatives as Antimicrobial Agents
Abu Mohsen, Usama; Yurttaş, Leyla; Acar, U.; Özkay, Yusuf; Kaplancıklı, Zafer Asım; Karaca Gencer, Hülya; Cantürk, Zerrin (Georg Thieme Verlag Kg, 2015)In this study, we aimed to synthesize some new quinoxaline derivatives bearing amide moiety and to evaluate their antimicrobial activity. A set of 16 novel compounds of N-[2,3-bis(4-methoxy/methylphenyl)quinoxalin-6-yl]- ... -
Synthesis and Characterization of Two New Thiophene Acetyl Salicylic Acid Esters and their ortho-and para-effect on Anticancer Activity
Ünver, Hakan; Cantürk, Zerrin (Bentham Science Publ LTD, 2017)Objective: The present study aimed to explore the cytotoxic effect of ortho-and para-positional isomers of thiophene acetyl salicylic acid esters against cancer and normal cell lines. Method: Two new thiophene-2-acetic ... -
Synthesis and Evaluation of Bis-pyrazoline Derivatives as Potential Antimicrobial Agents
Altıntop, Mehlika Dilek; Abu Mohsen, Usama; Karaca, Hülya; Cantürk, Zerrin; Özdemir, Ahmet (Bentham Science Publ LTD, 2014)In the present study, 5,5'-(1,4-phenylene)bis[3-(2-thienyl)-4,5-dihydro-1H-pyrazole-1-(4-arylthiazol-2-yl)] derivatives (3a-h) were obtained via the reaction of 5,5'-(1,4-phenylene)bis[3-(2-thienyl)-4,5-dihydro-1H-pyrazo ... -
Synthesis and Evaluation of New Thiazole Derivatives as Potential Antimicrobial Agents
Altıntop, Mehlika Dilek; Özdemir, Ahmet; Atlı Eklioğlu, Özlem; Cantürk, Zerrin; Baysal, Merve; Kaplancıklı, Zafer Asım (Bentham Science Publ LTD, 2016)In an effort to develop potent antimicrobial agents, new thiazolyl hydrazone derivatives were synthesized and investigated for their inhibitory effects on pathogenic bacteria and yeasts. MTT assay was carried out to determine ... -
Synthesis and Evaluation of Tetrazole-Based Hydrazone Derivatives Bearing a Pyridine Moiety as Antimicrobial Agents
Özdemir, Ahmet; Altıntop, Mehlika Dilek; Sever, Belgin; Cantürk, Zerrin; Kaplancıklı, Zafer Asım (Bentham Science Publ LTD, 2015)2-[(1-Methyl/Phenyl-1H-tetrazol-5-yl)thio]-N'-[(aryl) methylidene/ethylidene] acetohydrazides were synthesized and investigated in vitro against pathogenic bacteria and Candida species for their antimicrobial activity using ... -
Synthesis and In Vitro Evaluation of Furan-Based Chalcone Derivatives as Antimicrobial Agents
Özdemir, Ahmet; Altıntop, Mehlika Dilek; Cantürk, Zerrin; Kaplancıklı, Zafer Asım (Bentham Science Publ LTD, 2015)Some furan-based chalcone derivatives were synthesized via the Claisen-Schmidt condensation of 5-arylfurfural derivatives with 4'-cyanoacetophenone. The synthesized derivatives were investigated for their antimicrobial ... -
Synthesis and In Vitro Evaluation of New Thiosemicarbazone Derivatives as Potential Antimicrobial Agents
Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Sever, Belgin; Cantürk, Zerrin; Özdemir, Ahmet (Hindawi LTD, 2016)In an effort to develop potent antimicrobial agents, new thiosemicarbazone derivatives were synthesized via the reaction of 4-[4-(trifluoromethyl)phenyl]thiosemicarbazide with aromatic aldehydes. The compounds were evaluated ... -
Synthesis of New Fluoro-Benzimidazole Derivatives as an Approach towards the Discovery of Novel Intestinal Antiseptic Drug Candidates
Çevik, Ulviye Acar; Sağlık, Begüm Nurpelin; Özkay, Yusuf; Cantürk, Zerrin; Bueno, Juan; Demirci, Fatih; Koparal, Ali Savaş (Bentham Science Publ LTD, 2017)In the present study, nineteen new fluoro-benzimidazole derivatives, including nifuroxazide analogs, were synthesized by microwave-supported reactions and tested against a panel of pathogenic microorganisms consisting of ... -
Synthesis of novel thiazolylpyrazoline derivatives and evaluation of their antimicrobial activities and cytotoxicities
Tabbi, Aouatef; Kaplancıklı, Zafer Asım; Tebbani, Dahmane; Yurttaş, Leyla; Cantürk, Zerrin; Atlı Eklioğlu, Özlem; Turan, Gülhan (Scientific Technical Research Council Turkey-Tubitak, 2016)Several novel thiazolylpyrazoline derivatives were synthesized by reacting substituted 3,5-diaryl-1-thiocarbamoyl-2-pyrazolines with phenacylbromides. The structures of the synthesized compounds were confirmed by IR, H-1 ... -
Synthesis of novel thiazolylpyrazoline derivatives and evaluation of theirantimicrobial activities and cytotoxicities
Tabbı, Aouatef; Kaplancıklı, Zafer Asım; Tebbanı, Dahmane; Yurttaş, Leyla; Cantürk, Zerrin; Atlı Eklioğlu, Özlem; Turan, Gülhan (2016)Several novel thiazolylpyrazoline derivatives were synthesized by reacting substituted 3,5-diaryl-1-thiocarba-moyl-2-pyrazolines with phenacylbromides. The structures of the synthesized compounds were con rmed by IR,1HNMR,13C ...