Browsing by Author "Demirci, Fatih"
Now showing items 21-40 of 175
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Antioxidant activity of chamomile essential oil and main components
Fırat, Zeynep; Demirci, Fatih; Demirci, Betül (Badebio Biotechnololgy Ltd, 2018)The objective of this study was to characterize the antioxidant capacity of the chamomile (Matricaria recutita L.) essential oil (EO) as well as its major constituents. For this purpose, Pharmacopoeia grade Matricariae ... -
Antiproliferative and antiapoptotic effect of thymoquinone on cancer cells in vitro
Kuş, Gökhan; Özkurt, Mete; Kabadere, Selda; Erkasap, Nilüfer; Göğer, Gamze; Demirci, Fatih (Comenius University, 2018)OBJECTIVES: Nigella sativa oil and thymoquinone were comparatively tested in vitro for their effects on human cancer cell lines (glioma, T98; prostate, LnCaP) as well as mouse embryonic fi broblast cell lines (3T3), and ... -
Antiprotozoal Activity of Turkish Origanum onites Essential Oil and Its Components
Tasdemir, Deniz; Kaiser, Marcel; Demirci, Betuel; Demirci, Fatih; Baser, K. Huesnue Can (Mdpi, 2019)Essential oil of Origanum species is well known for antimicrobial activity, but only a few have been evaluated in narrow spectrum antiprotozoal assays. Herein, we assessed the antiprotozoal potential of Turkish Origanum ... -
Bazı bitkisel tentürlerde farmakope analizleri ve antimikrobiyal aktivite tayini
Demirci, Fatih; Anadolu Üniversitesi, Sağlık Bilimleri Enstitüsü; Henden, Barış (Anadolu Üniversitesi - Sağlık Bilimleri Enstitüsü, 2020)Bitkisel drog preparatı olarak tentürler, eczacılık ve fitoterapide binlerce yıllık bir kullanıma sahiptir. Gerek geleneksel, gerekse kanıta dayalı iyi tanımlanmış etkiye sahip tentürlerin günümüzde de terapötik olarak ... -
Betulenols from Betula species
Demirci, Betül; Başer, K. Hüsnü Can; Özek, Temel; Demirci, Fatih (Georg Thieme Verlag, 2000)The essential oils from buds of five Betula species growing in Turkey were investigated by CC-MS. A major component in the essential oils was shown to be 14-hydroxy-beta-caryophyllene (6). The structure of beta-betulenal ... -
The bioactive essential oil of Heracleum sphondylium L. subsp ternatum (Velen.) Brummitt
İşcan, Gökalp; Demirci, Fatih; Kürkçüoğlu, Mine; Kıvanç, Merih; Başer, K. Hüsnü Can (Walter De Gruyter GMBH, 2003)The essential oil of Heracleum sphondylium L. subsp. ternatum (Velen.) Brummit (Umbelliferae) was isolated from crushed seeds by means of hydrodistillation and analyzed by GC and GC/MS. Major components were identified as ... -
The bioactive essential oil of Heracleum sphondylium L. subsp. ternatum (Velen.) Brummitt
İşcan, Gökalp; Demirci, Fatih; Kürkçüoğlu, Mine; Kıvanç, Merih; Başer, K. Hüsnü Can (Verlag der Zeitschrift fur Naturforschung, 2003)The essential oil of Heracleum sphondylium L. subsp. ternatum (Velen.) Brummit (Umbelliferae) was isolated from crushed seeds by means of hydrodistillation and analyzed by GC and GC/MS. Major components were identified as ... -
Bioassays on Periploca graeca L. (Silk vine)
Silk vine, Periploca graeca L. (Asclepiadaceae) which is a poisonous plant, was collected in July 1997 from Eskisehir (Asagi Kuplu-Mayislar Village). The methanolic extracts of the air dried leaves and twigs were separately ... -
Biological Activities of Bellis perennis Volatiles and Extracts
Kavalcıoğlu, Neslihan; Açık, Leyla; Demirci, Fatih; Demirci, Betül; Demir, Hülya; Başer, K. Hüsnü Can (Natural Products Inc, 2010)Different parts of Bellis perennis were subjected to hydrodistillation and the products were subsequently analyzed by GC and GC/MS. Aqueous and methanol extracts were prepared from the aerial parts. Antioxidant ... -
Biological activity and essential oil composition of two new Tanacetum chiliophyllum (Fisch & Mey.) Schultz Bip. var. chiliophyllum chemotypes from Turkey
Polatoğlu, Kaan; Demirci, Betül; Demirci, Fatih; Gören, Nezhun; Başer, K. Hüsnü Can (Elsevier, 2012)Water-distilled essential oils from aerial parts of Tanacetum chiliophyllum (Fisch. & Mey.) Schultz Bip. var. chiliophyllum, from two different localities in Turkey were analyzed by GC and GC/MS. The flower and stem oils ... -
Biotransformation of (-)-(R)-a-Phellandrene: Antimicrobial Activity of Its Major Metabolite
İşcan, Gökalp; Kırımer, Neşe; Demirci, Fatih; Demirci, Betül; Noma, Yoshiaki; Başer, K. Hüsnü Can (Wiley-V C H Verlag GMBH, 2012)Terpene derivatives converted by microbial biotransformation constitute an important resource for natural pharmaceutical, fragrance, and aroma substances. In the present study, the monoterpene a-phellandrene was biotransformed ... -
Biotransformation of (-)-?-Pinene by Botrytis cinerea
Farooq, A.; Choudhary, M. I.; Atta-ur-Rahman; Ahmed, Z.; Tahara, S.; Farooq, A.; Demirci, Fatih (2002)(-)-?-Pinene (1), a major constituent of many aromatic plants was biotransformed by the plant pathogenic fungus, Botrytis cinerea to afford three new metabolites, characterized as 3ß-hydroxy-(-)-ß-pinene (10%) (3), ... -
Biotransformation of (-)-alpha-pinene by Botrytis cinerea
Farooq, A; Tahara, S; Choudhary, MI; Atta-ur-Rahman; Ahmed, Z; Başer, K. Hüsnü Can; Demirci, Fatih (Verlag Z Naturforsch, 2002)(-)-alpha-Pinene (1), a major constituent of many aromatic plants was biotransformed by the plant pathogenic fungus, Botrytis cinerea to afford three new metabolites, characterized as 3beta-hydroxy-(-)-beta-pinene (10%) ... -
Biotransformation of ?-cedrol and caryophyllene oxide by the fungus Neurospora crassa
Kıran, İsmail; Durceylan, Zeynep; Kırımer, Neşe; Başer, K. Hüsnü Can; Noma, Yoshiaki; Demirci, Fatih (2010)Incubation of ?-cedrol and caryophyllene oxide with Neurospora crassa afforded 12ß-hydroxy cedrol, 10?-hydroxy cedrol, and 3?-hydroxy cedrol, and 12ß-hydroxy caryophyllene oxide as major metabolites, respectively. The ... -
Biotransformation of abietic acid by fungi and biological evaluation of its metabolites
Özşen, Özge; Kıran, İsmail; Dağ, İlknur; Atlı Eklioğlu, Özlem; Çiftçi, Gülsen Akalın; Demirci, Fatih (Elsevier Sci LTD, 2017)Biotransformation of abietic acid was carried out initially using 28 different microbial strains. Among the evaluated, Mucor ramannianus produced a known metabolite namely 2 alpha-hydroxy-dehydroabietic acid whereas ... -
Biotransformation of alpha-Cedrol and Caryophyllene Oxide by the Fungus Neurospora crassa
Kıran, İsmail; Durceylan, Zeynep; Kırımer, Neşe; Başer, K. Hüsnü Can; Noma, Yoshiaki; Demirci, Fatih (Natural Products Inc, 2010)Incubation of a-cedrol and caryophyllene oxide with Neurospora crassa afforded 12 beta-hydroxy cedrol, 10 alpha-hydroxy cedrol, and 3 beta-hydroxy cedrol, and 12 beta-hydroxy caryophyllene oxide as major metabolites, ... -
Biyoaktif monoterpenlerin mikrobiyal transformasyonu
Demirci, Fatih (Anadolu Üniversitesi, 2000)Bu çalışmada, karvakrol (1), timol (2), karvakrol metil eter (3), timol metil eter (4), karvon enantiyomerleri (5, 5’) ve 55 farklı mikroorganizmayla gerçekleştirilen biyotransformasyonlarda oluşan 30 adet metabolit, ... -
Carbazoles and Hydrazone-Bridged Thiazole-Pyrrole Derivatives as New Inhibitors of alpha-Glucosidase
Ghani, Usman; Albarrag, Ahmed; Yurttaş, Leyla; Demirci, Fatih; Kaplancıklı, Zafer Asım (Wiley-V C H Verlag GMBH, 2018)Carbazoles and hydrazone-bridged thiazole-pyrrole derivatives are known to exhibit a wide range of biological activities including antimicrobial activity. This work is a further extension of their biological activities ... -
Characterization and Biological Activity of Achillea teretifolia Willd. and A. nobilis L. subsp neilreichii (Kerner) Formanek Essential Oils
Demirci, Fatih; Demirci, Betül; Gürbüz, İlhan; Yeşilada, Erdem; Başer, K. Hüsnü Can (Tubitak Scientific & Technical Research Council Turkey, 2009)The aerial parts of the endemic Achillea teretifolia Willd. and A. nobilis L. subsp. neilreichii (Kerner) Formanek collected from Beysehir were investigated for their essential oil compositions and several biological ... -
Characterization and Biological Activity of Achillea teretifolia Willd. and A. nobilis L. subsp. neilreichii (Kerner) Formanek Essential Oils
The aerial parts of the endemic Achillea teretifolia Willd. and A. nobilis L. subsp. neilreichii (Kerner) Formanek collected from Beysehir were investigated for their essential oil compositions and several biological ...