Yazar "Ilgın, Sinem" için listeleme
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Estrogenic effects of lycopene and beta-carotene on ER(+) HeLa and LNcaP cancer cells
Ilgın, Sinem; Ergün, Bülent; Korkmaz, Seval (Blackwell Publishing, 2006)… -
Evaluation of azithromycin induced cardiotoxicity in rats
Atlı Eklioğlu, Özlem; Ilgın, Sinem; Altuntaş, Hakan; Burukoğlu, Dilek (E-Century Publishing Corp, 2015)Although there are possible cardiovascular adverse effects associated with the azithromycin treatment according to some case reports and cohort studies, there is no experimental study evaluating cardiotoxicity in repeated ... -
Evaluation of hepatotoxicity associated with citalopram administration in rats
Baysal, Merve; Atlı Eklioğlu, Özlem; Dagasan, F.; Burukoğlu, D.; Ilgın, Sinem (Elsevier Ireland LTD, 2015)… -
Evaluation of in vitro hepatotoxicity of perampanel in comparison with carbamazepine: old versus new
Anadolu Üniversitesi; 0009-0003-0969-0474; 0000-0001-7331-1975; 0000-0002-3646-7935; 0000-0002-8099-0942; 0000-0002-0434-1334; 0000-0002-6131-3399; Farmanlı, Gülnar; Ilgın, Sinem; Ergun, Bülent; Baysal, Merve; Karaduman, Abdullah Burak; Atlı Eklioğlu, Özlem (Anadolu Üniversitesi, 2023)Since the liver metabolizes many drugs, including antiepileptics, this organ is the main target of drug-induced damage. There is very little data on hepatotoxicity due to carbamazepine and perampanel metabolized in the ... -
Evaluation of quetiapine-induced hepatotoxicity in rats
Ilgın, Sinem; Atlı Eklioğlu, Özlem; Burukoğlu, Dilek; Baysal, Merve; Hinis, O. (Elsevier Ireland LTD, 2015)… -
Evaluation of the reproductive toxicity of levetiracetam in male rats
Baysal, Merve; Ilgın, Sinem; Kılıç, Volkan; Kılıç, G.; Uçarcan, Şeyda; Atlı Eklioğlu, Özlem (Elsevier Ireland LTD, 2016)… -
Evaluation of the reproductive toxicity of naproxen sodium and meloxicam in male rats
Uzun, B.; Atlı Eklioğlu, Özlem; Perk, B. O.; Burukoğlu, D.; Ilgın, Sinem (SAGE Publications LTD, 2015)Nonsteroidal anti-inflammatory drugs that are cyclooxygenase (COX) enzyme inhibitors have generally been used in short-term pain management and also to treat inflammation chronically. It is known that COX enzyme and ... -
Evidence for cardiotoxicity associated with sertraline in rats
Ilgın, Sinem; Kılıç, Volkan; Baysal, Merve; Aydoğan Kılıç, Gözde; Uçarcan, Şeyda; Dermenci, Begüm; Atlı Eklioğlu, Özlem (Royal Soc Chemistry, 2018)Sertraline is an antidepressant that is frequently prescribed to treat depression, obsessive-compulsive disorder, panic disorder, and anxiety. This drug had a safe cardiotoxicity profile, until the reporting of cases of ... -
Evidence for neurotoxicity associated with amoxicillin in juvenile rats
Atlı Eklioğlu, Özlem; Demir-Özkay, U.; Ilgın, Sinem; Aydın, T. H.; Akbulut, E. N.; Şener, E. (SAGE Publications LTD, 2016)Amoxicillin (AMX) is one of the most commonly prescribed antibiotics for children, and childhood is the period to have the highest risk for toxicity cases including drug-induced adverse reactions. Some neurological adverse ... -
In vitro and in silico evaluation of new thiazole compounds as monoamine oxidase inhibitors
Sağlık, Begüm Nurpelin; Kaya Çavuşoğlu, Betül; Osmaniye, Derya; Levent, Serkan; Çevik, Ulviye Acar; Ilgın, Sinem; Öztürk, Yusuf (Academic Press Inc Elsevier Science, 2019)New twenty compounds bearing thiazole ring (3a-3t) were designed and synthesized as monoamine oxidase (MAO) inhibitors. The fluorometric enzyme inhibition assay was used to determine the biological effects of synthesized ... -
In vitro antitumor activity evaluation of some 1,2,4-triazine derivatives bearing piperazine amide moiety against breast cancer cells
Yurttaş, Leyla; Demirayak, Şeref; Ilgın, Sinem; Atlı Eklioğlu, Özlem (Pergamon-Elsevier Science LTD, 2014)A series of 1,2,4-triazine derivatives bearing piperazine amide moiety has been synthesized and investigated for their potential anticancer activities. 1-[4-(5,6-Bis(4-subtituted phenyl)-1,2,4-triazin-3-yl) piperazin- ... -
Is MCT-induced toxicity limited to the pulmonary vasculature?
Ilgın, Sinem; Atlı Eklioğlu, Özlem; Sırmagül, Başar; Yılmaz, E. Demirel (Elsevier Ireland LTD, 2011)… -
Is N-acetyl cysteine protective against monocrotaline-induced toxicity?
Karagöz, Şerife; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Perk, Başak Özlem; Burukoğlu, Dilek; Ergün, Bülent; Sırmagül, Başar (Taylor & Francis Inc, 2013)Monocrotaline (MCT) is a pyrrolizidine alkaloid which induces cardio-pulmonary toxicity and hepatotoxicity in animals and humans. MCT is frequently ingested because of food grain contamination accidentally or in the form ... -
Likopenin er (+) HeLa ve LNCaP kanser hücreleri üzerinde antikarsinojenik aktivitesinin değerlendirilmesi
Ilgın, Sinem (Anadolu Üniversitesi, 2004)Likopen domates başta olmak üzere kırmızı sebze ve meyvelerde bulunan kemopreventif ve antikarsinojenik etkili karotenoid yapılı biyoaktif bir bileşendir. Antikarsinojenik etkisi çeşitli hücre kültürü, hayvan modelleri ve ... -
MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains
Can, Özgür Devrim; Osmaniye, Derya; Özkay, Ümide Demir; Sağlık, Begüm Nurpelin; Levent, Serkan; Ilgın, Sinem; Kaplancıklı, Zafer Asım (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)In the present work, 15 new N'-(arylidene)-4-(1-(prop-2-yn-1-yl)-1H-benzo[dlimidazol-2-yl)benzohydrazide (4a-4o) were designed and synthesized. The structures of the synthesized compounds were elucidated using FT-IR, ... -
Matrix metalloproteinases are possible targets in monocrotaline-induced pulmonary hypertension: investigation of anti-remodeling effects of alagebrium and everolimus
Atlı Eklioğlu, Özlem; Ilgın, Sinem; Ergün, Bülent; Burukoğlu, Dilek; Musmul, Ahmet; Sırmagül, Başar (Turkish Soc Cardiology, 2017)Objective: In our study, sildenafil alone and everolimus or alagebrium in combination with sildenafil were investigated in terms of their additional therapeutic and anti-remodeling activity in monocrotaline-induced pulmonary ... -
A Model for Implementing Academic English Lessons: Anadolu University Case
Aydın, Belgin; İstifçi, İlknur (2018)This study aims to provide a model used by Modern Languages Department of Anadolu University School of Foreign Languages, in order to implement Academic English courses as a result of a curriculum renewal project started ... -
Neurotoxicity assessment of amoxicillin in juvenile rats
Atlı Eklioğlu, Özlem; Demir-Özkay, U.; Ilgın, Sinem; Aydın, H.; Akbulut, E. N.; Şener, E. (Elsevier Ireland LTD, 2015)… -
New 1,4-dihydro[1,8]naphthyridine derivatives as DNA gyrase inhibitors
Karaca Gencer, Hülya; Levent, Serkan; Çevik, Ulviye Acar; Özkay, Yusuf; Ilgın, Sinem (Pergamon-Elsevier Science LTD, 2017)Owing to the growing need for novel antibacterial agents, we synthesized a novel series of fluoroquinolones including 7-substituted-1-(2,4-difluoropheny1)-6-fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid ... -
A novel series of thiazolyl-pyrazoline derivatives: Synthesis and evaluation of antifungal activity, cytotoxicity and genotoxicity
Altıntop, Mehlika Dilek; Özdemir, Ahmet; Turan, Gülhan; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Demirel, Rasime; Kaplancıklı, Zafer Asım (Elsevier France-Editions Scientifiques Medicales Elsevier, 2015)In the current work, new thiazolyl pyrazoline derivatives (1-22) were synthesized and evaluated for their antifungal effects against pathogenic yeasts and molds using a broth microdilution assay. Ames assay was carried out ...