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Novel Benzylidene Thiazolidinedione Derivatives as Partial PPAR gamma Agonists and their Antidiabetic Effects on Type 2 Diabetes

Yasmin, Sabina; Capone, Fabio; Laghezza, Antonio; Dal Piaz, Fabrizio; Loiodice, Fulvio; Vijayan, Viswanathan; Lavecchia, Antonio (Nature Publishing Group, 2017)

Peroxisome proliferator-activated receptor gamma (PPAR gamma) has received significant attention as a key regulator of glucose and lipid homeostasis. In this study, we synthesized and tested a library of novel 5-benzylid ...