Yayıncı "MDPI" için listeleme
Toplam kayıt 41, listelenen: 1-20
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Antihyperalgesic Activity of Atomoxetine on Diabetes-Induced Neuropathic Pain: Contribution of Noradrenergic and Dopaminergic Systems
(MDPI, 2018)Atomoxetine is a selective noradrenaline reuptake inhibitor drug. Based on the knowledge that agents increasing monoamine levels in the central nervous system have therapeutic potential for neuropathic pain, it is planned ... -
Chemical Composition and Antibacterial Activity of Essential Oils from Ferula L. Species against Methicillin-Resistant Staphylococcus aureus
(MDPI, 2018)Essential oils (EOs) were obtained by hydrodistillation of various parts of Ferula ovina (Boiss.) Boiss., Ferula iliensis Krasn. ex. Korovin, and Ferula akitschkensis B. Fedtsch. ex Koso-Pol., collected in the flowering/budding ... -
Chemical Composition, Antifungal and Insecticidal Activities of Hedychium Essential Oils
(MDPI, 2013)The antimicrobial properties of essential oils have been documented, and their use as "biocides" is gaining popularity. The aims of this study were to analyze the chemical composition and assess the biological activities ... -
The Cross-Cultural Invariance of the Servant Leadership Survey: A Comparative Study across Eight Countries
(MDPI, 2017)This paper tests and confirms the cross-cultural equivalence of the Servant Leadership Survey (SLS) in eight countries and languages: The Netherlands, Portugal, Germany, Iceland, Italy, Spain, Turkey and Finland. A composite ... -
Cytotoxic Effect of Eudesmanolides Isolated from Flowers of Tanacetum vulgare ssp siculum
(MDPI, 2012)A phytochemical analysis of the dichloromethane extract from the flowers of a subspecies of Tanacetum vulgare growing in Sicily was carried out. Five known sesquiterpene lactones with the eudesmane skeleton have been ... -
Design, Synthesis and Biological Evaluation of Novel N-Pyridyl-Hydrazone Derivatives as Potential Monoamine Oxidase (MAO) Inhibitors
(MDPI, 2018)A new series of N-pyridyl-hydrazone derivatives was synthesized by using a simple and efficient method. The final compounds obtained were screened for their inhibitory potency against monoamine oxidase (MAO) A and B. The ... -
Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety
(MDPI, 2018)In an attempt to develop potent antitumor agents, new 1,3,4-thiadiazole derivatives were synthesized and evaluated for their cytotoxic effects on multiple human cancer cell lines, including the K562 chronic myelogenous ... -
Design, Synthesis, and Evaluation of a New Series of Thiazole-Based Anticancer Agents as Potent Akt Inhibitors
(MDPI, 2018)In an attempt to develop potent anticancer agents targeting Akt, new thiazole derivatives (1-10) were synthesized and investigated for their cytotoxic effects on A549 human lung adenocarcinoma, C6 rat glioma, and NIH/3T3 ... -
Design, Synthesis, and Neuroprotective Effects of a Series of Pyrazolines against 6-Hydroxydopamine-Induced Oxidative Stress
(MDPI, 2018)Parkinson's disease (PD) is a chronic, progressive, and age-related neurodegenerative disorder characterized by the loss of midbrain dopaminergic neurons caused by the accumulation of free radicals and oxidative stress. ... -
Designation of Environmental Impacts and Damages of Turbojet Engine: A Case Study with GE-J85
(MDPI, 2014)Between the troposphere and stratosphere layers of the atmosphere is a critical zone for collecting emissions and negative effects on the Earth (ecological, humanity, and resources). Aircrafts are the main causes of the ... -
Development of Validated and Stability-Indicating LC-DAD and LC-MS/MS Methods for Determination of Avanafil in Pharmaceutical Preparations and Identification of a Novel Degradation Product by LCMS-IT-TOF
(MDPI, 2018)Avanafil (AVA), one of the most effective drugs prescribed for erectile dysfunction, is a pyrimidine-derivative PDE5 inhibitor. In the current work, new LC methods were developed and validated for quantitative determination ... -
Economic and Environmental Optimization of an Airport Terminal Building's Wall and Roof Insulation
(MDPI, 2017)HVAC systems use the largest share of energy consumption in airport terminal buildings. Thus, the efficiency of the HVAC system and the performance of the building envelope have great importance in reducing the energy used ... -
The Effect of Agomelatine Treatment on Diabetes-Induced Cognitive Impairments in Rats: Concomitant Alterations in the Hippocampal Neuron Numbers
(MDPI, 2018)Researches that are related to the central nervous system complications of diabetes have indicated higher incidence of cognitive disorders in patients. Since the variety of nootropic drugs used in clinics is limited and ... -
Environmental Performance of Electricity Generation Based on Resources: A Life Cycle Assessment Case Study in Turkey
(MDPI, 2016)The aim of this paper was to determine how to change the environmental performance of electricity generation depending on the resources and their shares, in order to support decision-makers. Additionally, this paper presents ... -
A Hysteresis Model for Fixed and Sun Tracking Solar PV Power Generation Systems
(MDPI, 2018)In this study, a new solar photovoltaic (PV) panel output power model is proposed. The model is constructed as a function of ambient temperature and solar radiations for two types (fixed panel and sun tracking panel) of ... -
Improved Spatio-Temporal Linear Models for Very Short-Term Wind Speed Forecasting
(MDPI, 2016)In this paper, the spatio-temporal (multi-channel) linear models, which use temporal and the neighbouring wind speed measurements around the target location, for the best short-term wind speed forecasting are investigated. ... -
Intrinsic Metrics on Sierpinski-Like Triangles and Their Geometric Properties
(MDPI, 2018)The classical Sierpinski Gasket defined on the equilateral triangle is a typical example of fractals. Sierpinski-like triangles can also be constructed on isosceles or scalene triangles. An explicit formula for the intrinsic ... -
Molecular Docking Studies of Coumarins Isolated from Extracts and Essential Oils of Zosima absinthifolia Link as Potential Inhibitors for Alzheimer's Disease
(MDPI, 2019)Coumarins and essential oils are the major components of the Apiaceae family and the Zosima genus. The present study reports anticholinesterase and antioxidant activities of extracts and essential oils from aerial parts, ... -
Pharmacological and Toxicological Screening of Novel Benzimidazole-Morpholine Derivatives as Dual-Acting Inhibitors
(MDPI, 2017)The aim of this study was to investigate acetylcholinesterase (AChE), monoamine oxidase A (MAO-A), monoamine oxidase B (MAO-B), cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzyme inhibitory, and antimicrobial ... -
Quantum chemical and experimental studies on the mechanism of alkylation of beta-dicarbonyl compounds. The synthesis of five and six membered heterocyclic spiro derivatives
(MDPI, 2004)The alkylation of beta-dicarbonyl compounds in a K2CO3/DMSO system was found to afford O- and C-alkylated derivatives, depending on the type of the P-dicarbonyl compound involved. The alkyl derivatives obtained were used ...