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Antinociceptive activities of some triazole and pyrazoline moieties-bearing compounds
(Springer Birkhauser, 2012)This study was designed to evaluate the potential antinociceptive activities of some triazole-pyrazoline derivatives. All of the test compounds (100 mg/kg) increased the reaction times of mice in hotplate and tail-clip ... -
Effects of Some 1,3,5-Trisubstitued-2-pyrazoline Derivatives on Depression and Anxiety Parameters of Mice
(Pharmaceutical Soc Korea, 2009)The aim of the present study was examining the effects of some 1,3,5-trisubstituted-2-pyrazoline derivatives on depression, anxiety and spontaneous locomotor activity parameters of mice. None of the compounds was effective ... -
Synthesis and Antidepressant Activity Profile of Some Novel Benzothiazole Derivatives
(MDPI, 2017)Within the scope of our new antidepressant drug development efforts, in this study, we synthesized eight novel benzothiazole derivatives 3a-3h. The chemical structures of the synthesized compounds were elucidated by ... -
Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents
(MDPI AG, 2016)In the current work, new 1,3,4-thiadiazole derivatives were synthesized and investigated for their antinociceptive effects on nociceptive pathways of nervous system. The effects of these compounds against mechanical, thermal ... -
Synthesis of Some Novel Thiadiazole Derivative Compounds and Screening Their Antidepressant-Like Activities
(MDPI, 2018)Novel thiadiazole derivatives were synthesized through the reaction of acetylated 2-aminothiadiazole and piperazine derivatives. The chemical structures of the compounds were clarified by Infrared Spectroscopy (IR), H-1 ...