Browsing by Author "Kökten, Şule"
Now showing items 1-9 of 9
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2-aminoarilasilbenzotriazol ortamlı antranilik asit esterlerinin, tiyoesterlerinin, amitlerinin sentezi ve karakterizasyonu
Kökten, Şule (Anadolu Üniversitesi, 2013)Bakterilerin, bitkilerin ve hayvanların temel biyokimyasal reaksiyonlarında ara ürün olarak ortaya çıkanantranilik asit, doğada yaygın olarak bulunan birçok bileşiğin de başlangıç maddesidir. Bu bileşikler arasında ... -
Bazı yeni pirazol türevlerinin sentezi ve yapılarının aydınlatılması
Kökten, Şule (Anadolu Üniversitesi, 2008)Sübstitue pirazoller çok çeşitli biyolojik ve farmakolojik aktiviteler gösterirler ve hem ilaç hem de tarım endüstrisinde geniş bir uygulama alanına sahiptirler. Bu yüzden, bu bileşiklerin sentezi için geliştirilen yöntemler ... -
Highly Sensitive Electrochemical Determination of Acetaminophen in Pharmaceuticals by Poly[2, 5-di(2-Thiophenyl)-1-p-(Tolyl) Pyrrole] Modified Pencil Graphite Electrode
Görçay, Hakan; Çelik, İlhami; Yurdakul, Erman; Şahin, Yücel; Kökten, Şule (IEEE-Inst Electrical Electronics Engineers Inc, 2016)A novel and highly sensitive sensor based on poly[2, 5-di(2-thiophenyl)-1-p-(tolyl) pyrrole] was developed and successfully applied for the electrochemical determination of acetaminophen (AC) in pharmaceutical samples. The ... -
N-(2-Aminobenzoyl)benzotriazole mediated and t-BuOK promoted synthesis of 2-substituted quinolone 3-carboxylates
Kökten, Şule; Çelik, İlhami (Pergamon-Elsevier Science LTD, 2015)2-Substituted quinolone 3-carboxylates were obtained in moderate to good yields by the reaction of N-(2-aminobenzoyl)benzotriazoles with beta-ketoesters in the presence of t-BuOK in THF -
N-(alpha-Amidoalkyl)benzotriazole-mediated synthesis of beta '-amido beta-diketones: a general synthetic protocol for N-[beta-(3,5-di and 1,3,5-trisubstituted pyrazol-4-yl)alkyl] amides
Çelik, İlhami; Kanışkan, Nevin; Kökten, Şule (Pergamon-Elsevier Science LTD, 2009)Various beta '-amido-beta-diketones were first synthesized with N-(alpha-amidoalkyl)benzotriazole-mediated amidoalkylation of 1,3-diketones in moderate yields. These intermediates undergo rapid condensation with hydrazines ... -
A new protocol for the synthesis of primary, secondary and tertiary anthranilamides utilizing N-(2-aminoarylacyl)benzotriazoles
Kaniskan, Nevin; Kökten, Şule; Çelik, İlhami (Arkat Usa Inc, 2012)A convenient route for efficient conversion of unprotected anthranilic acids into the corresponding N-(2-aminoarylacyl)benzotrazoles is described. N-(2-Aminoarylacyl)benzotrazoles have been successfully used to synthesize ... -
A Simple, Mild, and Practical Method for the Esterification and Thioesterification of Anthranilic Acid Utilizing N-(2-Aminobenzoyl)benzotriazole
Kökten, Şule; Çelik, İlhami (Georg Thieme Verlag Kg, 2013)A convenient and efficient method for the preparation of anthranilic esters and anthranilic thioesters has been developed by the treatment of N-(2-aminobenzoyl)benzotriazoles with alcohols and thiols in the presence of ... -
Stereoselective and regioselective synthesis of N-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates
Özenç, Köseceli Ayşen; Çelik, İlhami; Kökten, Şule (Scientific Technical Research Council Turkey-Tubitak, 2017)N-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis-Hillman acetates and a suitable acylazole in the presence of K2CO3 as a base catalyst. ... -
Stereoselective and regioselective synthesis of NN-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates
N -Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis–Hillman acetates and a suitable acylazole in the presence of K2 CO3 as a base ...