Browsing by Author "Uçucu, Ümit"
Now showing items 1-20 of 29
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Anticholinesterase activity screening of some novel dithiocarbamate derivatives including piperidine and piperazine moieties
Levent, Serkan; Çevik, Ulviye Acar; Sağlık, Begüm Nurpelin; Özkay, Yusuf; Can, Özgür Devrim; Özkay, Ümide Demir; Uçucu, Ümit (Taylor & Francis LTD, 2017)The present study was undertaken to synthesize some novel lipophilic piperazine and piperidinedithiocarbamates and investigate their inhibitory potencies against cholinesterase enzymes. In the synthetic studies, 44 new ... -
Antihelminthic activity and QSARs, of some 2-alkyl-5-chloro-benzimidazole derivatives
Uçucu, Ümit; Işıkdağ, İlhan; Tanol, M. (1992)[No abstract available] -
Antimicrobial and anticancer effects of some 2-(substitutedsulfanyl)-N-(5-methyl-isoxazol-3-yl)acetamide derivatives
Özkay, Yusuf; Seller, Zerrin; Önder, Nur İpek; Tunalı, Yağmur; Karaca Gencer, Hülya; Işıkdağ, İlhan; Uçucu, Ümit (Springer Birkhauser, 2013)In the present study, some isoxazole-(benz)azole derivatives (3a-3j) were synthesized by considering antimicrobial and anticancer potencies of azole compounds. Chemical structures of obtained compounds (3a-3j) were confirmed ... -
Bazı 1-benzil-2-(sübstitüe)-4,5-difenil-1H-imizadol türevlerinin sentezleri ve analjezik etkilerinin araştırılması
Gündoğdu, Nalan (Anadolu Üniversitesi, 1999)Bu çalışmada, yirmisekiz adet 1,2,4,5-tetrasübsitüe-1H-imidazol bileşiği sentezlenmiştir. Sentezlenen bileşiklerden yirmiiki tanesi orijinaldir. Sentezlerde, önce benzaldehidden hereketle benzoin türevine ve bunun da ... -
Bazı 2-sübstitüe benzoksazol türevlerinin sentezleri ve fizikokimyasal parametrelerinin tayinleri üzerinde çalışmalar
Gündoğdu, Nalan (Anadolu Üniversitesi, 1995)Benzimidazol, benzotiyazol ve benzoksazol yapıları günümüzde bir çok ilacın ana yapısını oluşturmaktadır. Bunun nedeni, adı geçen yapıların, organizmanın ürettiği kimyasallara benzer özellikler gös- termesinden kaynaklanmaktadır. ... -
Bazı 2-sübstitüe-5,6-dikloro-1h-benzimidazol bileşiklerinin sentezleri, yapı aydınlatmaları toksisitesi ve antikanser etkisinin incelenmesi üzerine çalışmalar
Karabajak, Mohammad (Anadolu Üniversitesi, 2001)Bu tezde, ana yapıolarak 5,6-dikloro-1H-benzimidazol çekirdeğini içeren toplam 14 adet bileşik sentez edilmiştir. Bu bileşiklerden 9 adedi orijinal olup 5'ine liteartürde rastlanmıştır. Sentezlenen bileşiklerden orijinal ... -
Bazı 2-Sübstitüe-5-(Benzotiyazol-2-İl)-1H-Benzimidazol türevlerinin sentezleri ve antikanser etkilerinin incelenmesi
Uzun, Bilge (Anadolu Üniversitesi, 2014)Kanser, sağlıklı hücrelerdeki genetik bilgilerin çeşitli faktörlerle değişmesiyle hücrelerin bölünme kontrolünü kaybetmesi sonucunda, kontrolsüz olarak çoğalmasıyla oluşan bir hastalıktır. Cerrahi ve radyoterapi yöntemlerine ... -
Benzimidazol derivatives: Synthesis, antibacterial activity and QSARs of some 2-alkyl-5-chloro-benzimidazoles
Işıkdağ, İlhan; Uçucu, Ümit; Demirayak, Şeref; Çakır, B. (1989)[No abstract available] -
Biological activity of some 4,5-di and 2,4,5-trisubstituted imidazole derivatives: Antihelmintic activity
Uçucu, Ümit; Işıkdağ, İlhan; Çakır, B. (1988)[No abstract available] -
QSAR of inhibitory activities by 2,4,5-trisubstituted imidazole derivatives on tubifex worms
Işıkdağ, İlhan; Uçucu, Ümit; Gündoğdu, N. (1995)[No abstract available] -
QSAR of inhibitory activities by 2-substituted-4,5-difuryl imidazole derivatives on tubifex worms
Işıkdağ, İlhan; Uçucu, Ümit (1995)[No abstract available] -
QSAR of smooth muscle relaxation by 2,5-substituted-benzimidazole derivatives
Quantitative structure-activity anlayses were carried out for in vitro relaxant actions of a series of 2,5-substituted-benzimidazoles in rat duodenal smooth muscle. Analyses of simple and multiple linear regression models ... -
Studies of the synthesis of some 4,5-di and 2,4,5-trisubstituted imidazole derivatives
Işıkdağ, İlhan; Uçucu, Ümit; Çakır, B. (1989)[No abstract available] -
Studies on the synthesis of some 2,4,5-trisubstituted imidazole derivatives
Işıkdağ, İlhan; Uçucu, Ümit; Gündoğdu, N. (1994)[No abstract available] -
Studies on the synthesis of some 2-(1',3'-benzodioxol-5'yl)-benzimidazole, benzothiazole and benzoxazole derivatives
Işıkdağ, İlhan; Uçucu, Ümit; Ersan, S. (1991)[No abstract available] -
Synthesis and analgesic activities of 2-substituted-1H-phenantro [9,10- d] imidazoles
Işıkdağ, İlhan; Uçucu, Ümit; Özdemir, Ahmet; Meriç, Asiye; Öztürk, Yusuf; Aydın, Süleyman; Ergün, Bülent (1999)Some 2-substituted-1H-phenantro [9, 10-d] imidazole compounds were synthesized and their analgesic activities were determined on the Swiss albino mice (25-35 g) of either sex. In the synthesis, phenantrenequinone molecule ... -
Synthesis and analgesic activities of some 2-(benzazolylacetyl)amino-3-ethoxycarbonylthiophene derivatives
Demirayak, Şeref; Karaburun, AC; Kayagil, İsmail; Uçucu, Ümit; Arslan, Rana (Taylor & Francis LTD, 2005)In this study, some 2-[2-(benzazole-2-thioxy)acetylamino]-3-ethoxycai-bonylthiophene and 2-[2-(benzazole-1-yl)acetylamino]-3-ethoxycarbonylthiophene compounds were obtained by the reaction of 2-chloroacetylamino-3-ethoxy ... -
Synthesis and analgesic activity of some 1-benzyl-2-substituted-4,5-diphenyl-1H-imidazole derivatives
Uçucu, Ümit; Karaburun, N. G.; Işıkdağ, İlhan (2001)In this study, derivatives of 1-benzyl-2-substituted-4,5-diphenyl-1H-imidazole were synthesized and their analgesic activity assayed in two tests. 1,2,4,5-Tetrasubstituted imidazole compounds were obtained by the treatment ... -
Synthesis and antifungal activities of some aryl (3-methyl-benzofuran-2-yl) ketoximes
Benkli, Kadriye; Gündoğdu-Karaburun, N; Karaburun, Ahmet Çağrı; Uçucu, Ümit; Demirayak, Şeref; Kiraz, N (Pharmaceutical Society Korea, 2003)In this study, some aryl (3-methyl-benzofuran-2-yl) ketoximes and their. ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1-NMR, MASS spectroscopy and elemental analyses. ...