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Toplam kayıt 136, listelenen: 71-80
Synthesis and Anticandidal Activity of New Imidazole-Chalcones
(MDPI, 2018)
In the present work, 15 new 1-(4-(1H-imidazol-1-yl)phenyl)-3-(4-substituedphenyl) prop-2-en-1-one derivatives (3a-3o) were synthesized to evaluate their antifungal activity. Structures of newly synthesized imidazole ...
Potential inhibitors of human carbonic anhydrase isozymes I and II: Design, synthesis and docking studies of new 1,3,4-thiadiazole derivatives
(Pergamon-Elsevier Science LTD, 2017)
In the last years, inhibition of carbonic anhydrase (CA) has emerged as a promising approach for pharmacologic intervention in a variety of disorders such as glaucoma, epilepsy, obesity, and cancer. As a consequence, the ...
Synthesis and antifungal activity of new hydrazide derivatives
(Taylor & Francis LTD, 2013)
In this study, nine new hydrazide derivatives were synthesized. The reaction of 2-[(5,6,7,8-tetrahydronaphthalen-2-yl) oxy]acetohydrazide with various benzaldehydes or acetophenones resulted in N'-substituted-2-[(5,6,7,8 ...
Studies on hydrazone derivatives as antifungal agents
(Taylor & Francis LTD, 2008)
The increasing clinical importance of drug-resistant fungal pathogens has urged additional need to fungal research and new antifungal compound development. For this purpose, some N-(1-benzyl-2-phenylethylidene)-N'-[4-(ar ...
Synthesis and AChE-Inhibitory Activity of New Benzimidazole Derivatives
(MDPI, 2019)
Alzheimer's disease (AD), one of the main causes of aged dementia, is a progressive and degenerative neurological disorder characterized by loss of cognition and memory. Although the symptomatic treatment of AD, particularly ...
The synthesis of some new hydrazone derivatives containing the benzothiazole moiety
(Serbian Chemical Soc, 2012)
Hydrazones are an important class of compounds found in many synthetic. products. Due to their importance in synthetic chemistry, the present article reports the synthesis of a new series of ten compounds based on the ...
Synthesis and Evaluation of New 1,5-Diaryl-3-[4-(methyl-sulfonyl)phenyl]-4,5-dihydro-1H-pyrazole Derivatives as Potential Antidepressant Agents
(MDPI, 2015)
In an effort to develop potent antidepressant agents, new pyrazoline derivatives 2a-s were synthesized and evaluated for their antidepressant-like activity by tail suspension test (TST) and modified forced swimming test ...
Modification of intracellular free calcium in cultured F2408 embryo fibroblasts by 3-sub substituted-2-thiohydantoin derivatives
(Wiley, 2004)
3-substituted-2-thiohydantoin derivatives were synthesized and their Structures elucidated by IR, H-1-NMR spectroscopy and elemental analysis. The cytotoxicity of the 2-thiohydantoin derivatives to rat embryo fibroblasts ...
Synthesis and antibacterial activity of tert-butyl [1-benzyl-2[(4-aryl-2-thiazolyl)hydrazono]ethyl]carbamate derivatives
(Wiley-V C H Verlag GMBH, 2007)
The increasing clinical importance of drug-resistant fungal and bacterial pathogens has lent additional urgency to microbiological research and new antibacterial compound development. For this purpose, new tent-butyl[1-b ...
Synthesis and antımicrobial activity evaluation of new hydrazide derivatives
(2011)
Mevcut antibiyotiklere patojenlerin bakteriyel direnç geliştirmesi ciddi bir halk sağlığı tehditi oluşturmaktadır. Dolayısıyla, yeni antibiyotiklerin geliştirilmesi için dünya çapında yoğun çabalar devam etmektedir. Güçlü ...