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Toplam kayıt 26, listelenen: 1-10
Synthesis of Some Benzothiazole Based Piperazine-Dithiocarbamate Derivatives and Evaluation of Their Anticancer Activities
(Bentham Science Publ LTD, 2011)
Some benzothiazole derivatives bearing piperazine and dithiocarbamate moieties were synthesized in order to investigate their anticancer activity. The structures of the obtained compounds were confirmed by spectral data ...
Synthesis and Antimicrobial Evaluation of Some 2,5-Disubstituted Benzimidazole Derivatives
(Bentham Science Publ LTD, 2013)
Some benzimidazole derivatives bearing hydrazone moiety were synthesized and their in vitro antimicrobial activity was determined against various gram-positive and gram-negative bacteria, and fungi using microbroth dilution ...
Synthesis and Evaluation of Heterocycles Based Chalcone Derivatives as Anti-proliferative Agents
(Bentham Science Publ LTD, 2018)
Background: The lack of selectivity and development of drug-resistance encourage researchers to search for novel, more efficient and multi-targeted agents with less toxicity. Objective: In this paper, a series of novel ...
Synthesis and Biological Evaluation of Some New Amide Moiety Bearing Quinoxaline Derivatives as Antimicrobial Agents
(Georg Thieme Verlag Kg, 2015)
In this study, we aimed to synthesize some new quinoxaline derivatives bearing amide moiety and to evaluate their antimicrobial activity. A set of 16 novel compounds of N-[2,3-bis(4-methoxy/methylphenyl)quinoxalin-6-yl]- ...
Synthesis and biological evaluation of new pyrazolone Schiff bases as monoamine oxidase and cholinesterase inhibitors
(Academic Press Inc Elsevier Science, 2019)
In the current work, Schiff base derivatives of antipyrine were synthesized. The chemical characterization of the compounds was confirmed using IR, H-1 NMR, C-13 NMR and mass spectroscopies. The inhibitory potency of ...
Synthesis of some novel 2-substituted benzothiazole derivatives containing benzylamine moiety as monoamine oxidase inhibitory agents
(Taylor & Francis LTD, 2016)
In the present work, 12 new 2-(5-substituted-benzothiazol-2-ylsulfanyl)-N-(substitutedbenzyl)-N-(4-substitutedphenyl) acetamide derivatives (4a-l) was designed and synthesized. The structures of the synthesized compounds ...
Synthesis and Biological Evaluation of New Cholinesterase Inhibitors for Alzheimer's Disease
(MDPI, 2018)
Alzheimer's disease (AD) is a neurodegenerative disorder mostly influencing the elderly, and causes death due to dementia. The main pathogenic feature connected with the progression of this multifactorial disease is the ...
Synthesis and Biological Evaluation of a Series of Dithiocarbamates as New Cholinesterase Inhibitors
(Wiley-V C H Verlag GMBH, 2013)
In the present paper, a novel series of dithiocarbamates was synthesized via the treatment of 4-(trifluoromethyl)benzyl chloride with appropriate sodium salts of N,N-disubstituted dithiocarbamic acids. H-1 NMR, mass spectral ...
Synthesis and Evaluation of Anti-acetylcholinesterase Activity of Some Benzothiazole Based New Piperazine-dithiocarbamate Derivatives
(Georg Thieme Verlag Kg, 2015)
In this present study some benzothiazole derivatives bearing piperazine and thiocarbamate moieties were synthesized and their potential anticholinesterase properties were investigated. A set of 30 new compounds of ...