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Toplam kayıt 69, listelenen: 1-10
Synthesis and antimicrobial activity of 4-phenyl/cyclohexyl-5-(1-phenoxyethyl)-3-[N-(2-thiazolyl)acetamido]thio-4H-1,2,4-triazole derivatives
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2005)
The increasing clinical importance of drug-resistant fungal and bacterial pathogens has lent additional urgency to microbiological research and new antimicrobial compound development. For this purpose, new thiazole derivatives ...
Novel Naphthyridine-Hydrazone Derivatives and their Antimicrobial Activity
(2014)
Amaç: Bu çalışmada, on yeni Naftiridin-Hidrazon türevinin sentezi ve antimikrobiyal aktivitelerinin değerlendirilmesi amaçlanmıştır. Materyal ve Metod: Sentezlenen bileşiklerin yapıları 1H-NMR ve MS spectral verileri ile ...
Synthesis and biological activities of new hydrazide derivatives
(Taylor & Francis LTD, 2009)
The synthesis of a new series of imidazo[1,2-a]pyrazine-2-carboxylic acid arylidene-hydrazides is described. The chemical structures of the compounds were elucidated by IR, H-1-NMR, FAB(+)-MS spectral data. Their biological ...
Fighting Against Alzheimer's Disease: Synthesis of New Pyrazoline and Benzothiazole Derivatives as New Acetylcholinesterase and MAO Inhibitors
(Bentham Science Publ LTD, 2018)
Background: Alzheimer's Disease (AD) is a complicated neurodegenerative disorder with a multifaceted pathogenesis. AD, characterized by gradual memory loss, falling in language ability and other cognitive deterioration, ...
Synthesis and biological evaluation of some hydrazone derivatives as new anticandidal and anticancer agents
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2012)
New hydrazone derivatives were synthesized via the nucleophilic addition-elimination reaction of 2-[(1-methyl-1H-tetrazol-5-yl]thio)]acetohydrazide with aromatic aldehydes/ketones. The compounds were tested in vitro against ...
Synthesis of 1-acetyl-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives and evaluation of their anticancer activity
(Informa Healthcare, 2013)
In the present study, 1-acetyl-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives (1-6) were synthesized via the ring closure reaction of 1-(2-thienyl)-3-aryl-2-propen-1-ones with hydrazine hydrate in acetic acid. The chemical ...
Studies on 1,2,4-triazole derivatives as potential anti-inflammatory agents
(Wiley-V C H Verlag GMBH, 2007)
The reaction of acetic or propionic acid hydrazides with various aryl/alkyl isothiocyanates gave thiosemicarbazides which furnished the 1,2,4-triazoles by alkali cyclization. The 4-aryl/allcyl-5-(1phenoxyethyl)-3-[N-(sub ...
Synthesis and anticandidal activity of new triazolothiadiazine derivatives
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2011)
New triazolothiadiazine derivatives were synthesized via the ring closure reaction of 4-amino-5-substituted-2,4-dihydro-3H-1,2,4-triazol-3-thiones with phenacyl bromides. The compounds were tested in vitro against various ...
Synthesis and anti-nociceptive, anti-inflammatory activities of new aroyl propionic acid derivatives including N-acylhydrazone motif
(Springer Birkhauser, 2015)
In the present study, new 4-[4-[2-(2-(4-substituted benzylidene)hydrazinyl)-2-oxoethoxy]phenyl]-4-oxobutanoic acid derivatives were synthesized, and their anti-nociceptive and anti-inflammatory activities were investigated. ...
Synthesis, antimicrobial activity and cytotoxicity of some new carbazole derivatives
(Informa Healthcare, 2012)
In this work, some N-(9-Ethyl-9H-carbazole-3-yl)-2-(phenoxy) acetamide derivatives were synthesised and evaluated for their antimicrobial activity and cytotoxicity. The structural elucidation of the compounds was performed ...