Kurum Yazarı "Yazan, Yasemin" Scopus İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Bioavailability file: Piribedil [Biyoyararlanim dosyasi: Piribedil]
Demirel, Müzeyyen; Yazan, Yasemin (2001)Piribedil is a dopamin agonist with vasodilator activity and whose aqueous solubility is low and elimination half-life is short. It is widely used in cerebral ageing and in Parkinson's disease. Literature on physico-chemical ... -
Chitosan gel formulations containing egg yolk oil and epidermal growth factor for dermal burn treatment
Yenilmez, Evrim; Başaran, E.; Arslan, Rana; Berkman, Murat Sami; Güven, Umay Merve; Baycu, C.; Yazan, Yasemin (Govi-Verlag Pharmazeutischer Verlag GMBH, 2015)In the present study chitosan based gel formulations containing Egg Yolk Oil (EYO) and Epidermal Growth Factor (EGF) were formulated successfully aiming at enhanced topical treatment of dermal burns the combination of ... -
Chitosan nanoparticles for ocular delivery of cyclosporine A
Başaran, Ebru; Yenilmez, Evrim; Berkman, Murat Sami; Büyükköroğlu, Gülay; Yazan, Yasemin (Taylor & Francis LTD, 2014)In the present study, cyclosporine A (CsA) was successfully incorporated into cationic chitosan nanoparticles by spray-drying method aiming ocular application. Physicochemical characterisation of particles was performed ... -
Comparison of the bioavailability of oral and rectal forms of diphenylhydantoin sodium
Yazan, Yasemin; Erol, K. (Informa Healthcare, 1990)The bioavailabilities of single 100-mg oral and rectal doses of diphenylhydantoin sodium were studied in five healthy volunteers. The rectal form used was prepared at laboratory conditions and the oral form was a commercial ... -
Cyclosporine-A incorporated cationic solid lipid nanoparticles for ocular delivery
Başaran, Ebru; Demirel, Müzeyyen; Sırmagül, Başar; Yazan, Yasemin (Taylor & Francis LTD, 2010)In the present study, Cyclosporine A (CsA) was successfully incorporated into cationic solid lipid nanoparticles (SLN) for ocular application. Physicochemical characterizations of SLNs were analysed in detail during the ... -
Development and validation of uplc method for the determination of olopatadine hydrochloride in polymeric nanoparticles
Güven, Umay Merve; Berkman, Murat Sami; Yazan, Yasemin (İstanbul Medipol University, 2019)A new, simple, rapid, precise, accurate and specific stability indicating reverse phase UPLC method developed for the determination of encapsulated olopatadine hydrochloride (OLO) in the polymeric nanoparticle formulations. ... -
Dexketoprofen trometamol loaded solid lipid nanoparticles(SLNs): Formulation, in vitroand in vivoevaluation
Anadolu Üniversitesi, Eczacılık Fakültesi; 0000-0001-9596-0538; 0000-0002-7979-0089; 0000-0002-8041-6844; 0000-0001-9747-8307; 0000-0002-7492-1668; Öztürk, A. Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (2020)Development, in vitroand in vivoevaluation of dexketoprofen trometamol (DT)-loaded nanosizeddrugdelivery system was aimed in this study. DT-loaded solid lipid nanoparticles (SLNs) were prepared using probe ... -
Dexketoprofen trometamol-loaded eudragit® rl 100 nanoparticle formulation, characterization and release kinetics
Öztürk, Ahmet Alper; Yenilmez, Evrim; Yazan, Yasemin (İstanbul Medipol University, 2019)Development and in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized and controlled release drug delivery system was aimed in this study. DT-loaded Eudragit® RL 100 polymeric nanoparticles were prepared ... -
Dexketoprofen trometamol-loaded kollidon® SR and eudragit® RS 100 polymeric nanoparticles: Formulation and in vitro-in vivo evaluation
Öztürk, Ahmet Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon® SR (KSR) and Eudragit® RS 100 (ERS) ... -
Dexketoprofen trometamol-loaded poly-lactic-co-glycolic acid (PLGA) nanoparticles: Preparation, in vitro characterization and cyctotoxity
Öztürk, Ahmet Alper; Banderas, Lucia Martin; Otero, Maria D. Cayero; Yenilmez, Evrim; Senal, Behiye; Yazan, Yasemin (Pharmacotherapy Group, 2019)Purpose: To design, formulate and characterize sustained-release formulations of dexketoprofen trometamol (DT) nanoparticles (NPs) Methods: Dexketoprofen trometamol (DT)-loaded poly(lactic-co-glycolic acid) (PLGA) NPs were ... -
The effect of the type and the concentration of the lipophilic surfactant on the stability and release kinetics of the W/O/W multiple emulsions
Özer, O.; Baloğlu, E.; Ertan, G.; Muguet, V.; Yazan, Yasemin (2000)Stable multiple emulsions that contain different lipophilic surfactants in the internal aqueous phase have been formulated. The multiple systems were assessed by evaluating several parameters such as macroscopic aspect, ... -
Enhanced bioavailability of cinnarizine using solid dispersion: In vitro and in vivo evaluation
Demirel, Müzeyyen; Büyükköroğlu, G.; Sırmagül, Başar; Kalava, B. S.; Öztürk, Nilgün; Yazan, Yasemin (Bentham Science Publishers B.V., 2015)The aim of this study was to modify the release and thus enhance the bioavailability of acalcium antagonist cinnarizine whose aqueouse solubility is low and half-life is short. For this purpose, solid dispersion system was ... -
Enhancement in dissolution pattern of piribedil by molecular encapsulation with beta-cyclodextrin
Demirel, Müzeyyen; Büyükköroğlu, G; Kalava, BS; Yazan, Yasemin (Prous Science, Sa, 2006)The aim of this was to improve the dissolution behavior of piribedil by molecular encapsulation with beta-cyclodextrin (beta-CD). Toward this aim, physical mixing, co-grinding, and spray-drying methods were used to prepare ... -
Formulation and in vitro evaluation of moxifloxacin hydrochloride-loaded polymeric nanoparticles for ocular application
Yurtdaş Kırımlıoğlu, Gülsel; Özer, S.; Büyükköroğlu, G.; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)The primary purpose of this study was to extend the time of interaction of the carrier with the negatively charged ocular surface for enhanced penetration in order to improve ocular bioavailability. Moxifloxacin hydrochloride ... -
Formulation and in vitro-in vivo evaluation of piribedil solid lipid micro- and nanoparticles
Demirel, Müzeyyen; Yazan, Yasemin; Muller, RH; Kılıç, F; Bozan, B (Taylor & Francis LTD, 2001)Modification of the dissolution rate and, thus, the enhancement of the bioavailability of a dopaminergic drug, piribedil, which has a low aqueous solubility and short elimination half-life have been the aim in this study. ... -
Formulation and in-vivo evaluation of a cosmetic multiple emulsion containing vitamin C and wheat protein
Akhtar, Naveed; Yazan, Yasemin (University Karachi, 2008)The purpose of the study was to see the effect of two antiaging agents in one stable multiple emulsion prepared using natural oil. Vitamin C, which is a very unstable ingredient and is decomposed in the presence of oxygen, ... -
Gamma-aminobutyric acid loaded halloysite nanotubes and in vitro-in vivo evaluation for brain delivery
Kırımlıoğlu, Gülsel Yurtdaş; Yazan, Yasemin; Erol, Kevser; Unel, Çiğdem Cengelli (Elsevier Science BV, 2015)Gamma-aminobutyric acid (GABA) is a key neurotransmitter where it usually inhibits impulse transmission. GABA release blockage or postsynaptic reaction were determined to provoke epileptic convulsions. The aim of the present ... -
Improvement in the dissolution properties of theophylline with ß-cyclodextrin
Yazan, Yasemin; Sumnu, M. (1994)An improvement in the dissolution of theophylline with ß-cyclodextrin was achieved by subjecting them to co-grinding and freeze-drying methods. The products obtained were examined by the phase solubility methad, differential ... -
Improving sleep mask for eye contour care
Başyiğit, Zeynep Ömeroğulları; Hocaoğlu, E.; Kut, D.; Yenilmez, Evrim; Yazan, Yasemin (Fiber Society, 2015)[No abstract available] -
In vitro/in vivo evaluation of gamma-aminobutyric acid-loaded N,N-dimethylacrylamide-based pegylated polymeric nanoparticles for brain delivery to treat epilepsy
Kırımlıoğlu, Gülsel Yurtdaş; Menceloğlu, Yusuf; Erol, Kevser; Yazan, Yasemin (Taylor & Francis LTD, 2016)Objectives of this study were the delivery of gamma aminobutyric acid (GABA) into the brain by means of developing brain targeted, nanosized, non-toxic and biocompatible polymeric nanoparticles, and investigating their ...