Kurum Yazarı "Özdemir, Ahmet" WoS İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Synthesis and antimicrobial activity of some thiazolyl-pyrazoline derivatives
Kaplancıklı, Zafer Asım; Turan, Gülhan; Özdemir, Ahmet; Revıal, Gilbert; Güven, Kıymet (Taylor & Francis LTD, 2007)Some 1-(4-aryl-2-thiazolyl)-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives (TP 1-28) were synthesized by reacting substituted 3-(2-thienyl)-5-aryl-1-thiocarbamoyl-2-pyrazolines (P 1-7) with phenacyl bromides in ethanol. ... -
Synthesis and antinociceptive activities of some pyrazoline derivatives
Kaplancıklı, Zafer Asım; Turan, Gülhan; Özdemir, Ahmet; Can, Özgür Devrim; Chevallet, Pierre (Elsevier France-Editions Scientifiques Medicales Elsevier, 2009)In the present study, some pyrazoline derivatives were synthesized to investigate their potential antinociceptive activities. 1-[(Benzoxazole/benzimidazole-2-yl)thioacetyl]pyrazoline derivatives were obtained by reacting ... -
Synthesis and antiproliferative activity of new 1,5-disubstituted tetrazoles bearing hydrazone moiety
Kaplancıklı, Zafer Asım; Yurttaş, Leyla; Özdemir, Ahmet; Turan, Gülhan; Çiftçi, Gülsen Akalın; Yıldırım, Şafak Ulusoylar; Abu Mohsen, Usama (Springer Birkhauser, 2014)A new class of tetrazole-hydrazone derivatives including chloro-substituted phenyl moiety were synthesized to perform anticancer activity screening. The structural elucidation of the compounds was performed by IR, H-1 NMR, ... -
Synthesis and Antituberculosis Activity of New Hydrazide Derivatives
Kaplancıklı, Zafer Asım; Turan, Gülhan; Özdemir, Ahmet; Teulade, Jean-Claude (Wiley-V C H Verlag GMBH, 2008)The increasing clinical importance of drug-resistant mycobacterial pathogens, especially Mycobacterium tuberculosis, has lent additional urgency to microbiological research and new antimycobacterial compound development. ... -
Synthesis and antituberculosis activity of new thiazolylhydrazone derivatives
Turan, Gülhan; Özdemir, Ahmet; Kaplancıklı, Zafer Asım; Benkli, Kadriye; Chevallet, Pierre; Akalın Çiftçi, Gülsen (Elsevier France-Editions Scientifiques Medicales Elsevier, 2008)The increasing clinical importance of drug-resistant mycobacterial pathogens has lent additional urgency to microbiological research and new antimycobacterial compound development. For this purpose, new thiazolylhydrazone ... -
Synthesis and antituberculosis activity of some N-pyridyl-N '-thiazolylhydrazine derivatives
Turan, Gülhan; Kaplancıklı, Zafer Asım; Özdemir, Ahmet (Elsevier France-Editions Scientifiques Medicales Elsevier, 2010)In this study, new N-(1-arylethylidene)-N'-(4-arylthiazol-2-yl)hydrazine derivatives were synthesized and evaluated for their antituberculosis activity. The chemical structures of the compounds were elucidated by IR, NMR ... -
Synthesis and Antiviral Activity of Some (3,4-Diaryl-3H-Thiazol-2-Ylidene)Pyrimidin-2-Yl Amine Derivatives
Turan, Gülhan; Özdemir, Ahmet; Kaplancıklı, Zafer Asım (Taylor & Francis LTD, 2011)Thirteen new (3,4-diaryl-3H-thiazol-2-ylidene) pyrimidin-2-yl amine derivatives were synthesized by reacting 1-aryl-3-pyrimidin-2-yl-thiourea derivatives and phenacyl bromides in absolute ethanol. The solid that separated ... -
Synthesis and biological activities of new hydrazide derivatives
Özdemir, Ahmet; Turan, Gülhan; Kaplancıklı, Zafer Asım; Tunalı, Yağmur (Taylor & Francis LTD, 2009)The synthesis of a new series of imidazo[1,2-a]pyrazine-2-carboxylic acid arylidene-hydrazides is described. The chemical structures of the compounds were elucidated by IR, H-1-NMR, FAB(+)-MS spectral data. Their biological ... -
Synthesis and Biological Evaluation of a New Series of Pyrazolines as New Anticandidal Agents
Özdemir, Ahmet; Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım; Turan, Gülhan; Çiftçi, Gülsen Akalın; Demirci, Fatih (Springer, 2014)New pyrazoline derivatives bearing an oxadiazole moiety were synthesized via the reaction of 1-(chloroacetyl)-3-(2-furyl/thienyl)-5-aryl-2-pyrazolines with 5-substituted-1,3,4-oxadiazole-2(3H)-thiones in the presence of ... -
Synthesis and biological evaluation of new naphthalene substituted thiosemicarbazone derivatives as potent antifungal and anticancer agents
Altıntop, Mehlika Dilek; Atlı Eklioğlu, Özlem; Ilgın, Sinem; Demirel, Rasime; Özdemir, Ahmet; Kaplancıklı, Zafer Asım (Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)New thiosemicarbazone derivatives (1-10) were obtained via the reaction of 4-(naphthalen-1-yl)thiosemicarbazide with fluoro-substituted aromatic aldehydes. The synthesized compounds were evaluated for their in vitro ... -
Synthesis and Biological Evaluation of New Pyrazole-based Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
Altıntop, Mehlika Dilek; Özdemir, Ahmet; Ilgın, Sinem; Atlı Eklioğlu, Özlem (Bentham Science Publ LTD, 2014)New pyrazole-based thiazolyl hydrazone derivatives were obtained via the ring closure reaction of 3,5-dimethyl-1H-1-phenylpyrazole-4-carboxaldehyde thiosemicarbazone with 2-bromoacetophenone derivatives. The compounds were ... -
Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents
Erguc, Ali; Altıntop, Mehlika Dilek; Atlı Eklioğlu, Özlem; Sever, Belgin; İşcan, Gökalp; Gormus, Gözde; Özdemir, Ahmet (Bentham Science Publ LTD, 2018)Background: In medicinal chemistry, thiazoles have gained great importance in anti-fungal and anticancer drug design and development. Objectives: The aim of this study was to synthesize new quinoline-based thiazolyl hydrazone ... -
Synthesis and Biological Evaluation of Pyrazoline Derivatives Bearing an Indole Moiety as New Antimicrobial Agents
Özdemir, Ahmet; Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım; Turan, Gülhan; Karaca Gencer, Hülya; Tunalı, Yağmur (Wiley-V C H Verlag GMBH, 2013)1-(p-Methylphenyl)-3,5-diaryl-2-pyrazoline derivatives (2a-f) were synthesized via the treatment of 1-(1H-indol-3-yl)-3-aryl-2-propen-1-ones (1a-f) with p-methylphenylhydrazine hydrochloride in hot acetic acid. The structures ... -
Synthesis and Biological Evaluation of some Amide Derivatives Bearing Benzothiazole and Piperidine Moieties as Antimicrobial Agents
Altıntop, Mehlika Dilek; Özdemir, Ahmet; Kaplancıklı, Zafer Asım; Turan, Gülhan; İşcan, Gökalp; Çiftçi, Gülsen Akalın (Bentham Science Publ LTD, 2013)In this study, N-(benzothiazol-2-yl)-2-(piperidin-1-yl)acetamide derivatives (1-24) were obtained by the reaction of 2-chloro-N-(benzothiazole-2-yl)acetamides with piperidine derivatives. The structures of the compounds ... -
Synthesis and Biological Evaluation of Some Hydrazone Derivatives as Anti-inflammatory Agents
Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Özdemir, Ahmet; Turan, Gülhan; Khan, Shabana I.; Tabanca, Nurhayat (Bentham Science Publ LTD, 2012)In the present study, some hydrazone derivatives were synthesized via the reaction of 3-cyclohexylpropionic acid hydrazide with various benzaldehydes. The chemical structures of the compounds were elucidated by spectroscopic ... -
Synthesis and biological evaluation of some hydrazone derivatives as new anticandidal and anticancer agents
Altıntop, Mehlika Dilek; Özdemir, Ahmet; Turan, Gülhan; Ilgın, Sinem; Atlı Eklioğlu, Özlem; İşcan, Gökalp; Kaplancıklı, Zafer Asım (Elsevier France-Editions Scientifiques Medicales Elsevier, 2012)New hydrazone derivatives were synthesized via the nucleophilic addition-elimination reaction of 2-[(1-methyl-1H-tetrazol-5-yl]thio)]acetohydrazide with aromatic aldehydes/ketones. The compounds were tested in vitro against ... -
Synthesis and Biological Evaluation of Some Pyrazoline Derivatives Bearing a Dithiocarbamate Moiety as New Cholinesterase Inhibitors
Altıntop, Mehlika Dilek; Özdemir, Ahmet; Kaplancıklı, Zafer Asım; Turan, Gülhan; Temel, Halide Edip; Çiftçi, Gülsen Akalın (Wiley-V C H Verlag GMBH, 2013)In the present study, new pyrazoline derivatives were synthesized via the reaction of 1-(chloroacetyl)-3-(2-furyl)-5-aryl-2-pyrazolines with sodium salts of N,N-disubstituted dithiocarbamic acids. Each derivative was ... -
Synthesis and biological evaluation of some thiazole derivatives as new cholinesterase inhibitors
Turan, Gülhan; Özdemir, Ahmet; Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Temel, Halide Edip; Çiftçi, Gülsen Akalın (Informa Healthcare, 2013)In the present study, some thiazole derivatives were synthesized via the ring closure reaction of 1-[2-(2-oxobenzo[d] thiazol-3(2H)-yl)acetyl]thiosemicarbazide with various phenacyl bromides. The chemical structures of the ... -
Synthesis and Evaluation of a New Series of Arylidene Indanones as Potential Anticancer Agents
Özdemir, Ahmet; gökbulut, Sevtem; Sever, Belgin; Çiftçi, Gülsen Akalın; Altıntop, Mehlika Dilek (Bentham Science Publ LTD, 2018)Background: Arylidene indanones have attracted a great deal of interest due to their outstanding therapeutic applications. In particular, considerable research has pointed out the importance of arylidene indanones in the ... -
Synthesis and Evaluation of A New Series of Thiazole Derivatives as Potential Antitumor Agents and MMP Inhibitors
Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Atlı Eklioğlu, Özlem; Sever, Belgin; Baysal, Merve; Temel, Halide Edip; Özdemir, Ahmet (Bentham Science Publ LTD, 2017)Background: In recent years, the relationship between overexpression of matrix metalloproteinases ( MMPs) and tumor invasion/metastasis has prompted researchers to develop MMP inhibitors as anticancer drugs. Objective: The ...