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Toplam kayıt 19, listelenen: 1-10
Licofelone abolishes survival of carcinogenic fibroblasts by inducing apoptosis
(Informa Healthcare, 2014)
Dual inhibitors of cyclooxygenase (COX) and lipoxygenase (LOX) pathways of arachidonic acid metabolism prevent cancer development and induce apoptosis. One of the most promising compounds that blocks both of these pathways ...
The investigation of ceranib-2 on apoptosis and drug interaction with carboplatin in human non small cell lung cancer cells in vitro
(Springer, 2018)
Ceramide is found to be involved in inhibition of cell division and induction of apoptosis in certain tumour cells. Ceranib-2 is an agent that increases ceramide levels by inhibiting ceramidase in cancer cells. Therefore, ...
Possible Antiproliferative Effect of Tolfenamic Acid on Human LNCaP Prostate Cancer Cell Lines
(Zoological Soc Pakistan, 2019)
Prostate cancer is a common type of cancer. Contemporary treatment modalities require that new, effective methods or chemicals should be developed. Tolfenamic acid (TA) is a nonsteroidal anti-inflammatory medicine stimulating ...
Comparative Study on Induction of Apoptosis in A549 Human Lung Adenocarcinoma Cells by C2 Ceramide or Ceranib-2
(Zoological Soc Pakistan, 2017)
Investigation of ceramide and ceramidases on cancer therapy had become popular in recent years. Ceramide is a metabolite in sphingolipid pathway of the cells that has an ability to promote cell death in tumor cells when ...
Cytotoxic and Apoptotic Functions of Licofelone on Rat Glioma Cells
(Akademiai Kiado Zrt, 2013)
Gliomas are the largest group of central nervous system tumors and despite of clinical treatments death rate is very high. Inhibition of both cyclooxygenase and lipoxygenase pathways that take role in arachidonic acid ...
Comparing the Role of Silymarin on Survival Rate of Rat Glioma With Primary Mixed Rat Glia Cells in Vitro
(Parlar Scientific Publications (PSP), 2013)
Phytochemicals, nutraceuticals and herbal products, such as silymarin, have gained ever growing popularity and are valued for their ability to defend against almost all types of disease. Primarily known as hepatoprotective ...
Thymoquinone Inhibits the Proliferation and Induces Apoptosis of Cancer Cells in Vitro
(Wiley-Blackwell, 2015)
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Erythropoietin Protects the Kidney by Regulating the Effect of TNF-alpha in L-NAME-Induced Hypertensive Rats
(Karger, 2018)
Background/Aims: Hypertension is the leading cause of death worldwide. Chronic high blood pressure induces inflammation. Tumor necrosis factor (TNF)-alpha plays a major role in inflammation and also depresses the synthesis ...
Hepatosellüler Karsinom Hücrelerinde Karmofurun Sitotoksik ve Apoptotik Etkileri
(2017)
Bedende istenmeyen ve potansiyel olarak tehkike arze-den hücrelerin ölümünü sağlayan apoptotik hücre ölü-mü genetik olarak kontrol edilir ve bu yolla bedendeki hücrelerin sayısı kontrol altında tutulur. Apoptoz ölüm ...
Induction of apoptosis in prostate cancer cells by the novel ceramidase inhibitor ceranib-2
(Springer, 2015)
Ceramidases are key enzymes that decrease ceramide levels in cells. A reduction in ceramide concentration impairs ceramide signalling, and results in apoptosis resistance in cancer cells. This study investigates the potential ...