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Toplam kayıt 18, listelenen: 1-10
Analgesic and antispasmodic activities of 2-(2-nitro-phenyl)-1 H-benzimidazole 5-carboxylic acid: Evidence for the importance of the 2-(o-substituted phenyl) group
(2003)
Benzimidazole 5-carboxylic acid derivatives were investigated for analgesic activity in this study. Of the benzimidazole compounds tested, 2-(2-nitro-phenyl)-1 H-benzimidazole 5-carboxylic acid showed remarkable naloxone ...
Zonisamide: Antihyperalgesic efficacy, the role of serotonergic receptors on efficacy in a rat model for painful diabetic neuropathy
(Pergamon-Elsevier Science LTD, 2014)
Aims: The purpose of this study was to compare the changes of antihyperalgesic effectiveness of zonisamide (25 and 50 mg/kg), an antiepileptic drug, on the early and late phases of neuropathy and to investigate the role ...
Antinociceptive effect of methanol extract of Capparis ovata in mice
(Taylor & Francis LTD, 2010)
Context: Capparis ovata Desf. (Capparaceae) grows widely in Turkey. Flower buds and fruits of the plant are used in folk medicine for their analgesic, antirheumatismal, and diuretic effects. Objective:This study evaluated ...
The Centrally-Mediated Mechanisms of Action of Ferulic Acid-Induced Antinociception
(Marmara University, Fac Medicine, 2016)
This study aimed to investigate the central antinociceptive effects of ferulic acid, a common phenolic compound found in various medicinal plants used for pain relief, and the contribution of cholinergic, serotonergic, ...
Antithrombotic effects of ethanol extract of Crataegus orientalis in the carrageenan-induced mice tail thrombosis model
(Pergamon-Elsevier Science LTD, 2011)
Introduction: Crataegus species (common name is Hawthorn) are medicinal plants, which have flavonoids, triterpene acids, proanthocyanidins, and organic acids as main constituents, used in the treatment of cardiovascular ...
Hypoglycemic activity of Capparis ovata desf. var. palaestina zoh. methanol extract
(University Sao Paulo, Conjunto Quimicas, 2018)
Caper (Capparis ovata Desf. and Capparis spinosa L.) is naturally widespread in Turkey. Traditionally, buds, fruits, seeds and roots of this plant arc used as tonic, diuretic, anti-rheumatic, expectorant, antidiabetic, and ...
Potential Antithrombotic Effect of Crataegus Species
(Assoc Pharmaceutical Teachers India, 2018)
Hawthorn (Crataegus), a highly important medicinal and aromatic plant, has been used for many years in the treatment of various diseases. In folk medicine, hawthorn has been used to treat asthma, hyperlipidemia, heart ...
The Role of TRP and K+ Ion Channels in Analgesic Effect of NSAIDs
(Marmara University, Inst Health Sciences, 2018)
Objective: We aimed to clarify the possible contributions of TRP and voltage-dependent K+ channels to the analgesic effects of diclofenac, ketoprofen, etodolac, and dipyrone using the nonselective TRP channel blocker ...
The imidazoline receptors and ligands in pain modulations
(Wolters Kluwer Medknow Publications, 2015)
Pain is an unpleasant experience and effects daily routine negatively. Although there are various drugs, many of them are not entirely successful in relieving pain, since pain modulation is a complex process involving ...
The possible mechanisms of protocatechuic acid-induced central analgesia
(Elsevier Science BV, 2018)
It is aimed to investigate the central antinociceptive effect of protocatechuic acid and the involvement of stimulation of opioidergic, serotonin 5-HT2A/2C. alpha 2-adrenergic and muscarinic receptors in protocatechuic ...