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Toplam kayıt 31, listelenen: 1-10
Cytotoxic and inhibitory effects of pomegranate peel extract on proliferation of MCF-7 cells [Nar meyve kabugu ekstresi·ni·n mcf-7 hücre proli·ferasyonu üzeri·ne si·totoksi·k ve i·nhi·bi·tör etki·leri·]
(2008)
The Pomegranate (Punica granatum L.) is a wonderful fruit which contains a wide variety of precious phytochemical compounds applicable in the fields of therapeutics and health care. Previous studies have demonstrated the ...
Synthesis and Anticancer Activity of New Hydrazide-hydrazoncs and Their Pd(II) Complexes
(Bentham Science Publ LTD, 2019)
Background: Hydrazones, one of the important classes of organic molecules, are pharmaceutical agents comprising -CO-NH-N=CH- group in the structure therefore and exhibiting significant biological activity. Methods: ...
mTOR Inhibitors in the Treatment of Cancer
(Marmara University, Fac Pharmacy, 2015)
The mammalian target of rapamycin (mTOR) is a highly conserved in evolution serine/threonine kinase belonging to the phosphatidylinositol kinase related protein kinases family. mTOR plays a central role in regulation of a ...
Evaluation of the antileukemic effects of neurokinin-1 receptor antagonists, aprepitant, and L-733,060, in chronic and acute myeloid leukemic cells
(Lippincott Williams & Wilkins, 2019)
Neurokinin-1 receptor (NK1R) antagonists are known for their anxiolytic, antiemetic, anticancer, and antiinflammatory effects. Aprepitant is used in vomiting and nausea, which are the most common side-effects of patients ...
Isofuranodiene: A neuritogenic compound isolated from wild celery (Smyrnium olusatrum L., Apiaceae)
(Elsevier Sci LTD, 2016)
In the search for neuroactive compounds that mimic the nerve growth factor (NGF) activity for the protection against neurodegenerative diseases, the potential medicinal values of foods and plants attracts intense interest. ...
Antioxidant, Antiproliferative and Apoptotic Effects of Secondary Metabolites of Halotolerant Aspergillus terreus on Colon Adenocarcinoma Caco-2 Cells
(Asian Network Scientific Information-Ansinet, 2017)
Objective: This study aimed to investigate the antioxidant and anticancer effects of the secondary metabolites of halotolerant Aspergillus terreus-2 (hAt-2) on colon adenocarcinoma (Caco-2) cells. The hAt-2 was isolated ...
Comparison of the Effects of Curcumin and RG108 on NGF-Induced PC-12 Adh Cell Differentiation and Neurite Outgrowth
(Mary Ann Liebert, Inc, 2017)
DNA methyltransferases (DNMTs) are promising epigenetic targets for the development of novel drugs, especially for neurodegenerative disorders. In recent years, there has been increased interest in small molecules that can ...
Evaluation of neuritogenic activity of cultivated, wild and commercial roots of Gentiana lutea L.
(Elsevier Science BV, 2015)
Several natural products have been proven to prevent neurodegenerative disorders by potentiating the action of nerve growth factor (NGF). Among them, secoiridoids have recently attracted interest for their potential use ...
Evaluation of Antiangiogenic and Antimetastatic Effects of Penicillium chrysogenum Secondary Metabolites
(Medknow Publications & Media Pvt LTD, 2017)
Development of resistance to standard therapy and toxic side effects are the major challenges encountered in chemotherapy of colorectal cancer. Increasing evidence has shown the ability of natural products to overcome ...
Neuritogenic Activity of Epigallocatechin Gallate and Curcumin Combination on Rat Adrenal Pheochromocytoma Cells
(Parlar Scientific Publications (PSP), 2017)
Plant phytochemicals are important neuroprotective agents which mainly act as antioxidants by scavenging stress -induced free radicals in the brain. Phytochemicals from medicinal plants including epigallocatechin gallate ...