Synthesis of some pyrido- and pyrazino-benzimidazole derivatives and their antifungal activity

Abstract

Some 2-aryl-4-hydroxypyrido[1,2-a]benzimidazole and 1-substituted 3-arylpyrazino-[1,2-a]benzimidazole derivatives were synthesized using 1-(2-arylethan-2-on)2-acylbenzimidazole derivatives as starting materials. Antifungal activities of the compounds obtained were examined in vitro.