Kurum Yazarı "Temel, Halide Edip" Anadolu Üniversitesi Dergileri İçin Listeleme
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Comparison of apoptotic effects of lupeol on A549 and C6 cell lines
Ertorun, İpek (Anadolu Üniversitesi, 2024)Lupeol compound is a cyclic triterpene alcohol that is widely found in plants. The compound lupeol has been reported to exhibit antitumor, anti-inflammatory, anxiolytic, neuroprotective and hepatoprotective effects. Recent ... -
COX inhibitory profiles of a series of thiadiazole-benzothiazole hybrids
Anadolu Üniversitesi; 0000-0003-0280-5550; 0000-0002-5233-1165; Özdemir, Ahmet; Temel, Halide Edip (Anadolu Üniversitesi, 2024)In an endeavour to identify small molecule COX-1 inhibitors, a colorimetric assay protocol was applied for the in vitro evaluation of COX-1 and 2 inhibitory potential of a series of thiadiazole-benzothiazole hybrids. The ... -
Design, synthesis and in vitro COX inhibitory profiles of a new series of tetrazole-based hydrazones
Anadolu Üniversitesi, Eczacılık Fakültesi; Altıntop, Mehlika Dilek; Sever, Belgin; Temel, Halide Edip; Kaplancıklı, Zafer Asım; Özdemir, Ahmet (Anadolu Üniversitesi, 2022)Inhibition of cyclooxygenases (COXs), by selective and nonselective inhibitors, is a favorable approach for pharmacologic intervention in a variety of disorders such as cancer. For this purpose, a new class of tetrazole-hydrazone ... -
Screening of new morpholine dithiocarbamate derivatives bearing benzimidazole moiety for anticholinesterase potential
Anadolu Üniversitesi; 0000-0002-5233-1165; 0000-0001-9535-2508; 0000-0002-0957-6044; Temel, Halide Edip; Akalın Çiftçi, Gülşen; Yurttaş, Leyla (Anadolu Üniversitesi, 2023)Alzheimer’s disease (AD) is basically associated with disturbances of cholinesterase metabolism which result in acetylcholine deficiency. Target of acetylcholinesterase (AChE) inhibitors used in symptomatic therapy of ...