Gelişmiş Arama

Basit öğe kaydını göster

dc.contributor.authorKüçükboyaci, N.
dc.contributor.authorTuran, Dural, N. N.
dc.contributor.authorKöroğlu, A.
dc.contributor.authorİşcan, Gökalp
dc.contributor.authorAydın, Ahmet
dc.date.accessioned2019-10-19T14:16:14Z
dc.date.available2019-10-19T14:16:14Z
dc.date.issued2015
dc.identifier.issn1304530X
dc.identifier.urihttps://hdl.handle.net/11421/13105
dc.description.abstractThe aim of the present work was to examine antioxidant and antimicrobial properties of Tamus communis L. ssp. cretica (L.) Kit Tan (Dioscoreaceae). The applied methods for the antioxidant activity of aqueous extract from the aerial parts of the plant were 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging, flow injection analysis-luminol chemiluminescence (FIA-CL) and thiobarbituric acid (TBA) assays. Total phenolic content of the aqueous extract was determined with spectrophotometric method. The antimicrobial activity of the n-hexane, chloroform, ethyl acetate, and ethanol extracts of the aerial parts of the plant was assessed towards selected bacteria. In addition, mineral composition of the raw plant was examined by atomic absorption spectroscopy. Aqueous extract of T. communis ssp. Cretica was found to possess DPPH free radical scavenging activity (IC50= 2.85±1.30 mg/mL), inhibitory effect on H2O2- and HOCl-luminol chemiluminescence (-log IC50=3.8±0.09 and IC50=1.3x10-3±4.9x10-4 mg/mL), and inhibitory activity toward lipid peroxidation (IC50=3.82±1.67 µg/mL) compared to the references. Total phenolic content of the aqueous extract was found to be 56.66±0.21 mg gallic acid/g extract. The n-hexane, chloroform, ethyl acetate, and ethanol extracts showed moderate activity having MIC values of 250-500 µg/mL against selected microorganisms. According to our results of mineral composition, the raw plant has low amount of toxic elements (Pb, Cd and Al), macro (Ca and Mg), and microelements (Cu, Fe, Mn and Zn)en_US
dc.language.isoengen_US
dc.publisherTurkish Pharmacists Associationen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntimicrobial Activityen_US
dc.subjectAntioxidant Activityen_US
dc.subjectDioscoreaceaeen_US
dc.subjectMineral Analysisen_US
dc.subjectTamus Communis Ssp. Creticaen_US
dc.titleEvaluation of antioxidant and antimicrobial activities of Tamus communis L. ssp. cretica (L.) Kit Tan and its mineral composition [Tamus communis L. ssp. cretica (L.) Kit Tan’ın antioksidan ve antimikrobiyal aktivitelerinin değerlendirilmesi ve mineral kompozisyonu]en_US
dc.typearticleen_US
dc.relation.journalTurkish Journal of Pharmaceutical Sciencesen_US
dc.contributor.departmentAnadolu Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalıen_US
dc.identifier.volume12en_US
dc.identifier.issue2en_US
dc.identifier.startpage113en_US
dc.identifier.endpage122en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.contributor.institutionauthorİşcan, Gökalp


Bu öğenin dosyaları:

DosyalarBoyutBiçimGöster

Bu öğe ile ilişkili dosya yok.

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster