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dc.contributor.authorCan, Özgür Devrim
dc.contributor.authorÖztürk, Yusuf
dc.contributor.authorÖztürk, Nilgün
dc.contributor.authorSagratini, Gianni
dc.contributor.authorRicciutelli, Massimo
dc.contributor.authorVittori, Sauro
dc.contributor.authorMaggi, Filippo
dc.date.accessioned2019-10-19T14:16:30Z
dc.date.available2019-10-19T14:16:30Z
dc.date.issued2011
dc.identifier.issn0367-326X
dc.identifier.issn1873-6971
dc.identifier.urihttps://dx.doi.org/10.1016/j.fitote.2011.01.008
dc.identifier.urihttps://hdl.handle.net/11421/13171
dc.descriptionWOS: 000291140800009en_US
dc.descriptionPubMed ID: 21262331en_US
dc.description.abstractThis present study was undertaken to examine treating effects of St. John's Wort (SJW) extract on nociceptive perception of STZ-diabetic animals based on its potential antidiabetic and antinociceptive activities. One week administrations of SJW extract (125 and 250 mg/kg) induced significant decrease in high blood glucose levels of three weeks STZ-diabetic rats and improved their dysregulated metabolic parameters. In addition, SJW extract treatment caused restoration in the mechanical hyperalgesia of diabetic animals. These findings provide a rationale for the traditional use of SJW against diabetes and display the potential of this plant as a new drug candidate/source for the treatment of diabetic painen_US
dc.language.isoengen_US
dc.publisherElsevier Science BVen_US
dc.relation.isversionof10.1016/j.fitote.2011.01.008en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSt. John'S Worten_US
dc.subjectHypericum Perforatumen_US
dc.subjectDiabetes Mellitusen_US
dc.subjectRutinen_US
dc.subjectTail Pinchen_US
dc.subjectTail Flicken_US
dc.titleEffects of treatment with St. John's Wort on blood glucose levels and pain perceptions of streptozotocin-diabetic ratsen_US
dc.typearticleen_US
dc.relation.journalFitoterapiaen_US
dc.contributor.departmentAnadolu Üniversitesi, Eczacılık Fakültesi, Farmakoloji Anabilim Dalıen_US
dc.identifier.volume82en_US
dc.identifier.issue4en_US
dc.identifier.startpage576en_US
dc.identifier.endpage584en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.contributor.institutionauthorCan, Özgür Devrim
dc.contributor.institutionauthorÖztürk, Yusuf
dc.contributor.institutionauthorÖztürk, Nilgün


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