Ara
Toplam kayıt 66, listelenen: 41-50
Studies on the synthesis of some new antipyrine derivatives
(2001)
Some new 4-(4, 5-diarylimidazole-2-yl) antipyrine, 4-(5-substituted benzimidazole-2-yl) antipyrine and 4-(phenantroimidazole-2-yl) antipyrine derivatives were synthesised. The structure elucidations of the compounds were ...
Synthesis and antifungal activities of some aryl (3-methyl-benzofuran-2-yl) ketoximes
(Pharmaceutical Society Korea, 2003)
In this study, some aryl (3-methyl-benzofuran-2-yl) ketoximes and their. ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1-NMR, MASS spectroscopy and elemental analyses. ...
Some 3-alkyl-6-(2-aryl-2-oxo-1-ethyl)-7-oxothiazolo [4,5-d]pyrimidin-2(3H)-thione derivatives and their antimicrobial activities
(2005)
In this study, some 3-alkyl-6-(2-aryl-2-oxo-1-ethyl)-7-oxothiazolo [4,5-d]pyrimidin-2(3H)-thione derivatives have been synthesized by reacting 3-alkyl-7-oxothiazolo[4,5-d]pyrimidin-2(3H)-thiones with various ?-bromoacetophenones. ...
Thiazole-substituted benzoylpiperazine derivatives as acetylcholinesterase inhibitors
(Wiley, 2018)
Hit, Lead & Candidate Discovery After acetylcholine is released into the synaptic cleft, it is reabsorbed or deactivated by acetylcholinesterase (AChE). Studies on Alzheimer's disease (AD) in the mid-20th century proved ...
Pyridine-substituted thiazolylphenol derivatives: Synthesis, modeling studies, aromatase inhibition, and antiproliferative activity evaluation
(Wiley-V C H Verlag GMBH, 2018)
Drugs used in breast cancer treatments target the suppression of estrogen biosynthesis. During this suppression, the main goal is to inhibit the aromatase enzyme that is responsible for the cyclization and structuring of ...
Synthesis of some 6,8-diarylimidazo[1,2-a]pyrazine derivatives by using either reflux or microwave irradiation method and investigation of their anticancer activities
(Wiley, 2005)
In order to obtain some 6,8-diarylimidazo[1,2-a]pyrazines, 1-(2-aryl-2-oxoethyl)-2-aryloylimidazole derivatives were reacted with ammonium acetate in acetic acid by using a new method different from that found in the ...
Synthesis and antibacterial activities of some 1-[2-(substituted pyrrol- 1-yl)ethyl]-2-methyl-5-nitroimidazole derivatives
(Elsevier Masson SAS, 1999)
In this study, some 1-[2-(substituted pyrrol-1-yl)ethyl]-2-methyl-5- nitroimidazole derivatives were synthesized by reacting 2-(2-methyl-5-nitro- 1H-imidazolyl)ethylamine dihydrochloride, which was prepared using metronidazole, ...
Synthesis and cytotoxic and analgesic activities of some 1, 5-diaryl-3-ethoxycarbonylpyrrole derivatives
(2006)
Some 1,5-diaryl-3-ethoxycarbonyl-2-methylpyrrole derivatives were obtained by reacting 1-aryl-3-ethoxycarbonylpent-1,4-diones and a suitable aniline derivative or sulfanilamide under Paal-Knorr pyrrole synthesis conditions. ...
Synthesis and antitumor activity evaluation of new 2-(4-aminophenyl)benzothiazole derivatives bearing different heterocyclic rings
(Taylor & Francis LTD, 2015)
Twenty-five new N-[4-(benzothiazole-2-yl)phenyl]acetamide derivatives bearing different heterocyclic ring systems were synthesized using 2-(4-aminophenyl)benzothiazole structure as a pharmacophoric group. Final compounds ...
Synthesis of Some 4-Phenyl/Cyclohexyl-5-(L-Phenoxyethyl)-3-[(3,5-Diaryl-2-Pyrazolinyl)Acetyl]Thio-4h-L,2,4-Triazole Derivatives and their Antifungal Activity
(2011)
Triazol türevleri, azol antifungallerin en büyük kimyasal grubudur. Günümüzde flukonazol ve itrakonazol en sık kullanılan triazol türevleridir. Diğer antifungaller ile kıyaslandığında, düşük toksisite ve geniş etki spektrumuna ...