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Toplam kayıt 36, listelenen: 21-30
Antimicrobial activity and a SAR study of some novel benzimidazole derivatives bearing hydrazone moiety
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2010)
In this study 12 novel benzimidazole compounds bearing hydrazone moiety were synthesized in order to investigate their possible antibacterial and antifungal activity. Structures of the synthesized compounds were elucidated ...
Potential inhibitors of human carbonic anhydrase isozymes I and II: Design, synthesis and docking studies of new 1,3,4-thiadiazole derivatives
(Pergamon-Elsevier Science LTD, 2017)
In the last years, inhibition of carbonic anhydrase (CA) has emerged as a promising approach for pharmacologic intervention in a variety of disorders such as glaucoma, epilepsy, obesity, and cancer. As a consequence, the ...
Antimicrobial Activity of a New Series of Benzimidazole Derivatives
(Pharmaceutical Soc Korea, 2011)
Due to antimicrobial importance of benzimidazoles and hydrazones, some benzimidazole-hydrazone compounds were synthesized to screen their antimicrobial activity. Structures of the synthesized compounds were elucidated by ...
The synthesis of some new hydrazone derivatives containing the benzothiazole moiety
(Serbian Chemical Soc, 2012)
Hydrazones are an important class of compounds found in many synthetic. products. Due to their importance in synthetic chemistry, the present article reports the synthesis of a new series of ten compounds based on the ...
Synthesis and antiproliferative activity of new 1,5-disubstituted tetrazoles bearing hydrazone moiety
(Springer Birkhauser, 2014)
A new class of tetrazole-hydrazone derivatives including chloro-substituted phenyl moiety were synthesized to perform anticancer activity screening. The structural elucidation of the compounds was performed by IR, H-1 NMR, ...
Synthesis of New Benzothiazole Acylhydrazones as Anticancer Agents
(MDPI, 2018)
During the last five decades, a large number of BT (Benzothiazole) derivatives formed one of the eligible structures in medicinal chemistry as anticancer agents. Most of the studies reveal that various substitutions at ...
Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents
(MDPI AG, 2014)
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl) furan-2-yl) ...
Design and Synthesis of New 1,3,4-Oxadiazole - Benzothiazole and Hydrazone Derivatives as Promising Chemotherapeutic Agents
(Georg Thieme Verlag Kg, 2017)
Looking for new cytotoxic and antimicrobial agents with improved antitumor activity, a series of hydrazide and oxadiazole derivatives were designed and synthesized using 3-methoxyphenol as starting substance. Novel ...
Synthesis and Antimicrobial Activity of New Pyrimidine-Hydrazones
(Bentham Science Publ LTD, 2014)
The synthesis of twelve new pyrimidine hydrazone derivatives and subsequent evaluation of their antimicrobial activities were the aims of this present work. The intermediate product 2-[(pyrimidin-2-yl)thio]acetohydrazide ...
Antimicrobial and Cytotoxic Evaluation of New Quinazoline Derivatives
(Natural Products Inc, 2016)
The synthesis of nine new quinazoline derivatives (2a-21) and evaluation of their antimicrobial and cytotoxic activities were aims of the present work. For the synthesis of the compounds, 2-chloro-6,7-dimethoxyquinazolin-4-amine ...