Ara
Toplam kayıt 141, listelenen: 101-110
Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents
(MDPI AG, 2016)
In the current work, new 1,3,4-thiadiazole derivatives were synthesized and investigated for their antinociceptive effects on nociceptive pathways of nervous system. The effects of these compounds against mechanical, thermal ...
Synthesis of New Benzothiazole Acylhydrazones as Anticancer Agents
(MDPI, 2018)
During the last five decades, a large number of BT (Benzothiazole) derivatives formed one of the eligible structures in medicinal chemistry as anticancer agents. Most of the studies reveal that various substitutions at ...
Synthesis and Biological Evaluation of Novel Piperazine Containing Hydrazone Derivatives
(Hindawi LTD, 2016)
Some hydrazone derivatives were synthesized and their potential anticholinesterase activities were examined. A series of eleven new compounds of N'-(2,4-disubstitutedbenzylidene)-2-(4-(4-nitrophenyl)piperazin-1-yl)acetohydrazide ...
Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents
(MDPI AG, 2014)
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl) furan-2-yl) ...
Synthesis and biological evaluation of new naphthalene substituted thiosemicarbazone derivatives as potent antifungal and anticancer agents
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)
New thiosemicarbazone derivatives (1-10) were obtained via the reaction of 4-(naphthalen-1-yl)thiosemicarbazide with fluoro-substituted aromatic aldehydes. The synthesized compounds were evaluated for their in vitro ...
Synthesis and analgesic activity of some triazoles and triazolothiadiazines
(Elsevier Science Sa, 1999)
The synthesis of some triazoles and triazolothiadiazines starting from (5,6,7,8-tetrahydronaphthalen-2-yl)oxyacetic acid is described. The chemical structure of the compounds were elucidated by analytical, IR, H-1 NMR and ...
Antifungal Effects of Some Oxadiazole Derivatives on Pathogenic Molds
(2013)
Bazı oksadiazol türevleri Aspergillus parasiticus, Aspergillus flavus, Aspergillus niger, Fusarium solani, Fusarium moniliforme and Stachybotrys chartarum 'a karşı in vitro olarak test edilmiştir. Butün bileşikler en yüksek ...
Synthesis of Some 4-Phenyl/Cyclohexyl-5-(L-Phenoxyethyl)-3-[(3,5-Diaryl-2-Pyrazolinyl)Acetyl]Thio-4h-L,2,4-Triazole Derivatives and their Antifungal Activity
(2011)
Triazol türevleri, azol antifungallerin en büyük kimyasal grubudur. Günümüzde flukonazol ve itrakonazol en sık kullanılan triazol türevleridir. Diğer antifungaller ile kıyaslandığında, düşük toksisite ve geniş etki spektrumuna ...
Synthesis and evaluation of novel 2-[(1,2,4-triazol-3-yl)thio]acetamide derivatives as potential serum paraoxonase-1 (PON1) activators
(Marmara University, Fac Pharmacy, 2017)
Coronary artery disease and low-density lipoprotein (LDL) levels in the blood have long been known to be associated with peripheral vascular diseases. Paraoxonase-1 (PON1) enzyme is related to serum levels of high-density ...
Design and Synthesis of New 1,3,4-Oxadiazole - Benzothiazole and Hydrazone Derivatives as Promising Chemotherapeutic Agents
(Georg Thieme Verlag Kg, 2017)
Looking for new cytotoxic and antimicrobial agents with improved antitumor activity, a series of hydrazide and oxadiazole derivatives were designed and synthesized using 3-methoxyphenol as starting substance. Novel ...