Ara
Toplam kayıt 141, listelenen: 11-20
Synthesis and Evaluation of a Series of 1,3,4-Thiadiazole Derivatives as Potential Anticancer Agents
(Bentham Science Publ LTD, 2018)
Background and Methods: In an attempt to develop potent antitumor agents, the synthesis of a series of N-(6-substituted benzothiazol-2-yl)-2-1(5-(arylamino)-1,3,4-thiadiazol-2-yl)thiolacetamides (1-14) was described and ...
Synthesis of some 4-phenyl/cyclohexyl-5-(l-phenoxyethyl)-3-[(3,5- diaryl-2-pyrazolinyl)acetyl]thio-4h-l,2,4-triazole derivatives and their antifungal activity [Bazi{dotless} 4-fenil/siklohegzil-5-(1-fenoksietil)-3-[(3,5-diaril-2-pirazolinil)aseti l]tiyo-4h-1,2,4-triazol türevlerinin sentezleri ve antifungal etkileri]
(2011)
Triazole derivatives are the major chemical group of antifungal azole derivatives. Nowadays, the most frequently used triazoles are fluconazole and itraconazole. They posses a broad spectrum of antifungal activity and ...
Synthesis and Evaluation of Tetrazole-Based Hydrazone Derivatives Bearing a Pyridine Moiety as Antimicrobial Agents
(Bentham Science Publ LTD, 2015)
2-[(1-Methyl/Phenyl-1H-tetrazol-5-yl)thio]-N'-[(aryl) methylidene/ethylidene] acetohydrazides were synthesized and investigated in vitro against pathogenic bacteria and Candida species for their antimicrobial activity using ...
Synthesis and Mosquitocidal Activity of a Series of Hydrazone Derivatives against Aedes aegypti
(Bentham Science Publ LTD, 2018)
Background: Aedes aegypti is an important mosquito vector for the transmission of several infectious diseases. Current insecticides play a vital role in controlling mosquitoes; however, the frequent use of insecticides has ...
Synthesis and In Vitro Evaluation of Furan-Based Chalcone Derivatives as Antimicrobial Agents
(Bentham Science Publ LTD, 2015)
Some furan-based chalcone derivatives were synthesized via the Claisen-Schmidt condensation of 5-arylfurfural derivatives with 4'-cyanoacetophenone. The synthesized derivatives were investigated for their antimicrobial ...
Studies on some new pyrazolo[3,4-c]pyridine derivatives as antimicrobial agents [Antimikrobiyal ajan olarak bazi yeni pirazolo[3,4-c]piridin türevleri üzerine çahsmalar]
(2009)
The increasing clinical importance of drug-resistant bacterial and fungal pathogens has lent additional urgency to microbiological research and novel antimicrobial compounds development. For this aim, a series of N-[(Benzhydryl) ...
Studies on thiazolyliminothiazoline derivatives as potential antitubercular agents
(2009)
In this study, eight new ethyl {2-[3,4-diaryl-3H-thiazol-2-ylidenamino] thiazol-4-yl}acetate were synthesized by reacting ethyl [2-(3-aryl(thiouredio) thiazol-4-yl]acetate and phenacyl bromides in ethanol. The solid was ...
Synthesis and Evaluation of New Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
(Bentham Science Publ LTD, 2017)
Background: In recent years, thiazole derivatives incorporated with hydrazone moiety have attracted a great deal of interest due to their pivotal role in the field of current cancer research. Methods: In the present study, ...
Synthesis and Evaluation of Heterocycles Based Chalcone Derivatives as Anti-proliferative Agents
(Bentham Science Publ LTD, 2018)
Background: The lack of selectivity and development of drug-resistance encourage researchers to search for novel, more efficient and multi-targeted agents with less toxicity. Objective: In this paper, a series of novel ...
Synthesis, Antibacterial, Antifungal, Antimycobacterial Activity Evaluation of Novel 1,2,4-triazole Derivatives Bearing 4-Aminophenyl Moiety
(Bentham Science Publ LTD, 2017)
Background: In this work, 2-[[5-(4-aminophenyl)-4-(4-substituted phenyl)-4H-1,2,4-triazol- 3-yl] thio]-1-(4-substituted phenyl) ethan-1-one derivatives (1-15) and 2-[[5-(4-aminophenyl)-4-( 4-substituted phenyl)-4H-1,2,4- ...