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Toplam kayıt 141, listelenen: 41-50
Synthesis and Antifungal Potential of Some Novel Benzimidazole-1,3,4-Oxadiazole Compounds
(MDPI, 2019)
Discovery of novel anticandidal agents with clarified mechanisms of action, could be a rationalist approach against diverse pathogenic fungal strains due to the rise of resistance to existing drugs. In support to this ...
Synthesis and Biological Evaluation of New Cholinesterase Inhibitors for Alzheimer's Disease
(MDPI, 2018)
Alzheimer's disease (AD) is a neurodegenerative disorder mostly influencing the elderly, and causes death due to dementia. The main pathogenic feature connected with the progression of this multifactorial disease is the ...
Synthesis and anti-nociceptive, anti-inflammatory activities of new aroyl propionic acid derivatives including N-acylhydrazone motif
(Springer Birkhauser, 2015)
In the present study, new 4-[4-[2-(2-(4-substituted benzylidene)hydrazinyl)-2-oxoethoxy]phenyl]-4-oxobutanoic acid derivatives were synthesized, and their anti-nociceptive and anti-inflammatory activities were investigated. ...
Synthesis, antimicrobial activity and cytotoxicity of some new carbazole derivatives
(Informa Healthcare, 2012)
In this work, some N-(9-Ethyl-9H-carbazole-3-yl)-2-(phenoxy) acetamide derivatives were synthesised and evaluated for their antimicrobial activity and cytotoxicity. The structural elucidation of the compounds was performed ...
Synthesis and Biological Evaluation of Pyrazoline Derivatives Bearing an Indole Moiety as New Antimicrobial Agents
(Wiley-V C H Verlag GMBH, 2013)
1-(p-Methylphenyl)-3,5-diaryl-2-pyrazoline derivatives (2a-f) were synthesized via the treatment of 1-(1H-indol-3-yl)-3-aryl-2-propen-1-ones (1a-f) with p-methylphenylhydrazine hydrochloride in hot acetic acid. The structures ...
New Thiazoline-Tetralin Derivatives and Biological Activity Evaluation
(MDPI AG, 2018)
In this study, novel N-(3-cyclohexyl/phenyl-4-(substituted phenyl)thiazole-2(3H)-ylidene)-2-[(5,6,7,8-tetrahydronaphthalen-2-yl)oxy]acetohydrazide (4a-4k) derivatives were synthesized and their anticancer potency were ...
Synthesis and anticandidal evaluation of new benzothiazole derivatives with hydrazone moiety
(Taylor & Francis LTD, 2016)
In this study, we have performed the synthesis of new N-(arylidene)-4-[(benzothiazol-2-yl)thio]butanoylhydrazide derivatives (3a-s) bearing azole moiety and hydrazone group in a lipophilic structural framework. The target ...
Synthesis and Biological Evaluation of a Series of Dithiocarbamates as New Cholinesterase Inhibitors
(Wiley-V C H Verlag GMBH, 2013)
In the present paper, a novel series of dithiocarbamates was synthesized via the treatment of 4-(trifluoromethyl)benzyl chloride with appropriate sodium salts of N,N-disubstituted dithiocarbamic acids. H-1 NMR, mass spectral ...
Synthesis of Oxadiazole-Thiadiazole Hybrids and Their Anticandidal Activity
(MDPI AG, 2017)
In the field of infection management, it is a major challenge to discover a potent and safe antifungal agent due to the emergence of resistant strains. Hence, the goal of this paper is to design and synthesize novel ...
Synthesis of some novel Carbazole derivatives and evaluation of their antimicrobial activity [Bazi{dotless} yeni karbazol türevlerinin sentezleri ve antimikrobiyal aktivitelerinin araşti{dotless}li{dotless}lmasi{dotless}]
(2011)
Carbazole and its derivatives are an important type of nitrogen containing aromatic heterocyclic compounds which have attracted considerable attention of medicinal chemists due to their antimicrobial activities. For this ...