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Toplam kayıt 48, listelenen: 31-40
Preparation of Some Thiazolyl Hydrazone Derivatives and Evaluation of Their Antibacterial Activities
(Taylor & Francis LTD, 2009)
The increasing clinical importance of drug-resistant fungal and bacterial pathogens has provided additional urgency to microbiological research and to the development of new antibacterial compounds. For this purpose, new ...
Design, synthesis and evaluation of new thiazole-piperazines as acetylcholinesterase inhibitors
(Informa Healthcare, 2013)
In this study, some new 2-(4-substituted piperazine-1-yl)-N-[4-(2-methylthiazol-4-yl)phenyl]acetamide derivatives were synthesized. The synthesized compounds were screened for their anticholinesterase activity on ...
Synthesis and biological evaluation of some thiazole derivatives as new cholinesterase inhibitors
(Informa Healthcare, 2013)
In the present study, some thiazole derivatives were synthesized via the ring closure reaction of 1-[2-(2-oxobenzo[d] thiazol-3(2H)-yl)acetyl]thiosemicarbazide with various phenacyl bromides. The chemical structures of the ...
Some 3-alkyl-6-(2-aryl-2-oxo-1-ethyl)-7-oxothiazolo [4,5-d]pyrimidin-2(3H)-thione derivatives and their antimicrobial activities
(2005)
In this study, some 3-alkyl-6-(2-aryl-2-oxo-1-ethyl)-7-oxothiazolo [4,5-d]pyrimidin-2(3H)-thione derivatives have been synthesized by reacting 3-alkyl-7-oxothiazolo[4,5-d]pyrimidin-2(3H)-thiones with various ?-bromoacetophenones. ...
Synthesis and antituberculosis activity of some N-pyridyl-N '-thiazolylhydrazine derivatives
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2010)
In this study, new N-(1-arylethylidene)-N'-(4-arylthiazol-2-yl)hydrazine derivatives were synthesized and evaluated for their antituberculosis activity. The chemical structures of the compounds were elucidated by IR, NMR ...
Synthesis and anticancer activity evaluation of N-[4-(2-methylthiazol-4-yl)phenyl]acetamide derivatives containing (benz)azole moiety
(Informa Healthcare, 2014)
A new class of novel thiazole-(benz) azole derivatives was synthesized to investigate their anticancer activity. The structure of the compounds was confirmed by IR, H-1-NMR, and MS spectral data and elemental analyses. ...
Thiazole-substituted benzoylpiperazine derivatives as acetylcholinesterase inhibitors
(Wiley, 2018)
Hit, Lead & Candidate Discovery After acetylcholine is released into the synaptic cleft, it is reabsorbed or deactivated by acetylcholinesterase (AChE). Studies on Alzheimer's disease (AD) in the mid-20th century proved ...
Synthesis and antibacterial activity of tert-butyl [1-benzyl-2[(4-aryl-2-thiazolyl)hydrazono]ethyl]carbamate derivatives
(Wiley-V C H Verlag GMBH, 2007)
The increasing clinical importance of drug-resistant fungal and bacterial pathogens has lent additional urgency to microbiological research and new antibacterial compound development. For this purpose, new tent-butyl[1-b ...
Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents
(MDPI AG, 2014)
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl) furan-2-yl) ...
Synthesis and antimicrobial activity of 1-(4-aryl-2-thiazolyl)-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2007)
Several 1-(4-aryl-2-thiazolyl)-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives were synthesized by reacting substituted 3-(2-thienyl)-5-aryl-lthiocarbarnoyl-2-pyrazolines with phenacyl bromides in ethanol. The structures of ...