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Synthesis and cytotoxic activities of transition-metal complexes of a binaphthyl-linked bipyridine ligand
(2009)
A binaphthyl-linked bipyridyl compound, 1,1?-bis(6-methyl-6?-oxymethylenyl- 2,2?-bipyridine)binaphthyl, (L) has been synthesised and used as a ligand for the formation of Cu(II), Ni(II), and Co(II) complexes. The ligand ...
Studies on some new pyrazolo[3,4-c]pyridine derivatives as antimicrobial agents [Antimikrobiyal ajan olarak bazi yeni pirazolo[3,4-c]piridin türevleri üzerine çahsmalar]
(2009)
The increasing clinical importance of drug-resistant bacterial and fungal pathogens has lent additional urgency to microbiological research and novel antimicrobial compounds development. For this aim, a series of N-[(Benzhydryl) ...
Synthesis of some 2,4-di- and 2,3,4-trisubstituted benzimidazo[1,2-a] pyrimidines and evaluation of their cytotoxicities towards F2408 and 5RP7 cells
(SYSCOM 18 S.R.L., 2006)
This article describes the synthesis of 2,4-di- and 2,3,4-trisubstituted benzimidazo[1,2-a]pyrimidine derivatives which were tested for their cytotoxicities and their spectral characterizations by IR, 1H- and 13C-NMR, ...
Studies on thiazolyliminothiazoline derivatives as potential antitubercular agents
(2009)
In this study, eight new ethyl {2-[3,4-diaryl-3H-thiazol-2-ylidenamino] thiazol-4-yl}acetate were synthesized by reacting ethyl [2-(3-aryl(thiouredio) thiazol-4-yl]acetate and phenacyl bromides in ethanol. The solid was ...
Synthesis of platinum(II) complexes of 1-aryl-3-(benzimidazole-2-yl)- pyrazole-4-ketoximes and studies on their cytotoxic effects
(2008)
In this research, synthesis of some complexes in the presence ofPt(II) were studied. The structure of the compounds were elucidated by IR, 1H-NMR, Mass and Elemental Analyses. The cytotoxicity of Pt-complex was evaluated. ...
Synthesis and characterization of new binaphthyl-linked phenanthroline-, bipyridine-, or pyridine-derived ligands, and the study of their cytotoxic activity
(2008)
In the present work, we describe the synthesis and characterization of five new versatile acyclic or macrocyclic ligands containing binaphthyl-linked pyridine, bipyridine, or phenanthroline groups in their framework (see ...
Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors
(Elsevier Masson SAS, 2019)
Epidermal growth factor receptor (EGFR, also known as HER1) and HER2, prominent members of receptor tyrosine kinase (RTK) superfamily, have been reported as diagnostic or prognostic markers in tumor progression. Based on ...
Synthesis, molecular docking analysis and carbonic anhydrase I-II inhibitory evaluation of new sulfonamide derivatives
(NLM (Medline), 2019)
New sulfonamide-hydrazone derivatives (3a-3n) were synthesized to evaluate their inhibitory effects on purified human carbonic anhydrase (hCA) I and II. The inhibition profiles of the synthesized compounds on hCA I-II ...
Synthesis of novel N-(naphthalen-1-yl)propanamide derivatives and evaluation their antimicrobial activity
(Taylor and Francis Ltd., 2019)
New N-(naphthalen-1-yl)propanamide was synthesized and studied for their antimicrobial activity. The final compounds were procured by reacting N-(naphthalen-1-yl)propanamide with some 2-mercapto aryl or dithiocarbamate ...
Synthesis of novel thiazolylpyrazoline derivatives and evaluation of theirantimicrobial activities and cytotoxicities
(2016)
Several novel thiazolylpyrazoline derivatives were synthesized by reacting substituted 3,5-diaryl-1-thiocarba-moyl-2-pyrazolines with phenacylbromides. The structures of the synthesized compounds were con rmed by IR,1HNMR,13C ...