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Toplam kayıt 5, listelenen: 1-5
Synthesis and evaluation of new benzimidazole derivatives with hydrazone moiety as anticancer agents
(Walter De Gruyter GMBH, 2018)
Objectives: Cancer is one of the leading causes of death throughout the world. Current therapy options suffer from the major limitations of side effects and drug resistance. Thus, continuing search for newer and safer ...
Synthesis and Antifungal Potential of Some Novel Benzimidazole-1,3,4-Oxadiazole Compounds
(MDPI, 2019)
Discovery of novel anticandidal agents with clarified mechanisms of action, could be a rationalist approach against diverse pathogenic fungal strains due to the rise of resistance to existing drugs. In support to this ...
Synthesis and Anticandidal Activity Evaluation of New Benzimidazole-Thiazole Derivatives
(MDPI, 2017)
Azole-based antifungal agents constitute one of the important classes of antifungal drugs. Hence, in the present work, 12 new benzimidazole-thiazole derivatives 3a-3l were synthesized to evaluate their anticandidal activity ...
Synthesis of New Fluoro-Benzimidazole Derivatives as an Approach towards the Discovery of Novel Intestinal Antiseptic Drug Candidates
(Bentham Science Publ LTD, 2017)
In the present study, nineteen new fluoro-benzimidazole derivatives, including nifuroxazide analogs, were synthesized by microwave-supported reactions and tested against a panel of pathogenic microorganisms consisting of ...
Synthesis and AChE-Inhibitory Activity of New Benzimidazole Derivatives
(MDPI, 2019)
Alzheimer's disease (AD), one of the main causes of aged dementia, is a progressive and degenerative neurological disorder characterized by loss of cognition and memory. Although the symptomatic treatment of AD, particularly ...