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Toplam kayıt 7, listelenen: 1-7
Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents
(Bentham Science Publ LTD, 2018)
Background: In medicinal chemistry, thiazoles have gained great importance in anti-fungal and anticancer drug design and development. Objectives: The aim of this study was to synthesize new quinoline-based thiazolyl hydrazone ...
Synthesis and Evaluation of New Thiazole Derivatives as Potential Antimicrobial Agents
(Bentham Science Publ LTD, 2016)
In an effort to develop potent antimicrobial agents, new thiazolyl hydrazone derivatives were synthesized and investigated for their inhibitory effects on pathogenic bacteria and yeasts. MTT assay was carried out to determine ...
Synthesis and Evaluation of New Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
(Bentham Science Publ LTD, 2017)
Background: In recent years, thiazole derivatives incorporated with hydrazone moiety have attracted a great deal of interest due to their pivotal role in the field of current cancer research. Methods: In the present study, ...
Synthesis and Biological Evaluation of New Pyrazole-based Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
(Bentham Science Publ LTD, 2014)
New pyrazole-based thiazolyl hydrazone derivatives were obtained via the ring closure reaction of 3,5-dimethyl-1H-1-phenylpyrazole-4-carboxaldehyde thiosemicarbazone with 2-bromoacetophenone derivatives. The compounds were ...
Synthesis and antimicrobial activity of some new hydrazone-bridged thiazole-pyrrole derivatives
(Taylor & Francis LTD, 2013)
In this work, we synthesized fourteen different compounds which contain hydrazone bridged thiazole and pyrrole rings. For this purpose, pyrrole-2-carboxaldehydes were reacted directly with thiosemicarbazide in ethanol and ...
Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents
(MDPI AG, 2014)
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl) furan-2-yl) ...
Synthesis and anti-Candida activity of novel 2-hydrazino-1,3-thiazole derivatives
(Pergamon-Elsevier Science LTD, 2013)
Eighteen new hydrazino-1,3-thiazole derivatives were evaluated against 8 strains of multi-resistant Candida spp. Introduction of an indolyl moiety linked to the hydrazone function enhanced the in vitro anti-Candida activity, ...