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dc.contributor.authorAydın, Süleyman
dc.contributor.authorSeker, E
dc.date.accessioned2019-10-19T14:43:53Z
dc.date.available2019-10-19T14:43:53Z
dc.date.issued2005
dc.identifier.issn0031-7144
dc.identifier.urihttps://hdl.handle.net/11421/13261
dc.descriptionWOS: 000226895000012en_US
dc.descriptionPubMed ID: 15739906en_US
dc.description.abstractThe aqueous distillate of Origanum onites L. (Labiatae) was reported to have various ethnomedical uses including effects on the gastrointestinal tract. The effects of three different doses (0.1, 0.2 and 0.4 mL) of the aqueous distillate of Origanum onites on isolated rat fundus, duodenum and ileum against acetylcholine induced contractions were investigated in this study. The aqueous distillate inhibited contractions in a dose dependent manner. Inhibitions were lowest on fundus. Carvacrol, being the major compound of the test substance, did not inhibit acetylcholine induced contractions of the isolated rat fundus, indicating the presence of other active principles including menthane diols. As being one of the first pharmacological studies on aqueous distillates, a possible pharmacological activity of cis-p-menth-4-ene-1,2-diol and 3,7-dimethyl-l-octen-3,7-diol is proposed in this study.en_US
dc.language.isoengen_US
dc.publisherGovi-Verlag Pharmazeutischer Verlag GMBHen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleEffect of an aqueous distillate of Origanum onites L. on isolated rat fundus, duodenum and ileum: Evidence for the role of oxygenated monoterpenesen_US
dc.typearticleen_US
dc.relation.journalPharmazieen_US
dc.contributor.departmentAnadolu Üniversitesi, Eczacılık Fakültesi, Farmakoloji Anabilim Dalıen_US
dc.identifier.volume60en_US
dc.identifier.issue2en_US
dc.identifier.startpage147en_US
dc.identifier.endpage150en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.contributor.institutionauthorAydın, Süleyman


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