Browsing Makale Koleksiyonu by Title
Now showing items 39-58 of 76
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Microencapsulation of ketorolac tromethamine by means of a coacervation phase separation technique induced by the addition of non-solvent
(Taylor & Francis LTD, 1998)Ketorolac tromethamine (KT) is a non-steroidal drug with potent analgesic and anti-inflammatory activity and is absorbed rapidly (T-max (1.0h) with an efficiency >87% following oral and intramuscular administration. The ... -
New Approach to Hypertension Treatment: Carvediol-Loaded PLGA Nanoparticles, Preparation, In Vitro Characterization and Gastrointestinal Stability
(Colegio Farmaceuticos Provincia De Buenos Aires, 2018)Carvedilol (CVL) has advantages over the first generation of beta-blockers in patients with heart failure due to its properties of reducing cardiovascular morbidity and mortality. On the other hand, CVL has a short half-life ... -
New approach to hypertension treatment: Carvediol-loaded PLGA nanoparticles, preparation, in vitro characterization and gastrointestinal stability
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)Carvedilol (CVL) has advantages over the first generation of ß-blockers in patients with heart failure due to its properties of reducing cardiovascular morbidity and mortality. On the other hand, CVL has a short half-life ... -
The next generation of skin antiaging dermacosmetic products [Cilt yaşlanmasi{dotless} karşi{dotless}ti{dotless} dermakozmetik ürünlerde gelecek jenerasyon]
(Turkiye Klinikleri, 2008)Among the visible changes frequently seen in aged skin are roughness in skin surface, widening of pores, sagging with wrinkling, excess skin on eyelids, downward mouth, double chin, color changes such as paling, darkening ... -
Ocular Application of Dirithromycin Incorporated Polymeric Nanoparticles: an In Vitro Evaluation
(Turkish Pharmacists Assoc, 2017)Objectives: Ocular drug delivery is a difficult challenge especially with topical intillation which results in rapid drainage and non-productive drug absorption. For the improvement of the pre-corneal retention time and ... -
Olopatadine hydrochloride loaded Kollidon (R) SR nanoparticles for ocular delivery: Nanosuspension formulation and in vitro-in vivo evaluation
(Elsevier Science BV, 2019)Introduction: Allergic eye diseases includes a spectrum of diseases, with each state being characterized by a complicated immunopathology. In the present study, polymeric Kollidon (R) SR nanoparticles loaded with olopatadine ... -
Ornidazole Incorporated Chitosan Nanoparticles for Ocular Application
(Colegio Farmaceuticos Provincia De Buenos Aires, 2015)Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ... -
Ornidazole incorporated chitosan nanoparticles for ocular application
(Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2015)Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ... -
Physicochemical characterization and dissolution properties of cinnarizine solid dispersions
(2005)Sudaki çözünürlüğü düşük olarak bilinen kalsiyum antagonisti sinnarizinin biyoyararlanımı değişken veya düşüktür. Bu özellikteki bir ilaç materyalinin çözünme davranışının iyileştirilmesi, oral biyoyararlanımı geliştirebilir. ... -
A polarographic study on dipyridamole and its determination in commercial tablets
(1991)The direct current polarographic behaviour of dipyridamole, a coronary vasodilator, in the supporting electrolyte consisting of 0.2 M KC1, 20 % (v/v) ethanol and buffer solutions is described in this study. Morphologically ... -
A Polarographic Study on Dipyridamole and Its Determination in Commercial Tablets
(Marcel Dekker Inc, 1991)The direct current polarographic behaviour of dipyridamole, a coronary vasodilator, in the supporting electrolyte consisting of 0.2 M KCl, 20% (v/v) ethanol and buffer solutions is described in this study. Morphologically ... -
Polymeric Cyclosporine-A Nanoparticles for Ocular Application
(Amer Scientific Publishers, 2011)In the present study, cyclosporine A (CsA) was incorporated successfully into cationic Eudragit(R) RS 100 nanoparticles (EPNs) aiming ocular application. Physicochemical characterization of the EPNs prepared was performed ... -
Preparation and characterization of methotrexate-loaded microcapsules
(Taylor & Francis LTD, 2014)Methotrexate (MTX) has toxic effect to healthy tissues. Microencapsulation coats particles with a functional coat to optimize storage stability and to modulate release. In the present study, a new MTX encapsulated microcapsules ... -
Preparation and characterization of polymeric and lipid nanoparticles of pilocarpine HCl for ocular application
(Informa Healthcare, 2013)Pilocarpine is used topically in the treatment of glaucoma. Various studies were performed to improve the bioavailability and prolong the residence time of drugs in ocular drug delivery. Drug loaded polymeric and lipid ... -
Preparation and in vitro characterization of a fluconazole loaded chitosan particulate system
(İstanbul Medipol University, 2019)In the present study fluconazole (FZ) was successfully incorporated into cationic chitosan nanoparticles prepared by spray-drying method aiming dermal delivery. Particle size and zeta potential measurements, drug content, ... -
Preparation and in vitro evaluation of controlled release hydrophilic matrix tablets of ketorolac tromethamine using factorial design
(Informa Healthcare, 2008)Controlled release matrix tablets of ketorolac tromethamine (KT) were prepared by direct compression technique using cellulose derivatives as hydroxypropylmethyl cellulose (HPMC), hydroxyethyl cellulose (HEC), and carboxymethyl ... -
Preparation and in vitro evaluation of in situ gelling system containing lithium carbonate for parenteral administration
(Springer Verlag, 2019)Lithium is the principal and the most effective drug in the treatment of bipolar disorder since the middle of the previous century. However, narrow therapeutic range and side effect profile of lithium necessitate its careful ... -
Preparation of prolonged release clarithromycin microparticles for oral use and their in vitro evaluation
(Pharmaceutical Soc Korea, 2006)Prolonged release microparticles of clarithromycin (CL) were prepared using Eudragit RL 100 and RS 100 by spray-drying and casting-drying techniques. For the characterization of those microparticles, preparation yield, ... -
Preparation, Characterization and In Vitro Evaluation of Dirithromycin Loaded Eudragit (R) RS 100 Nanoparticles for Topical Application
(Colegio Farmaceuticos Provincia De Buenos Aires, 2017)The purpose of the study was to formulate dirithromycin (DR) loaded Eudragit (R) RS 100 (ERS) nanoparticles for topical application and to analyze the physical and chemical characteristics and in vitro toxicity of the ... -
Propranolol HCl imprinted polymeric microspheres: Development, characterization and dissolution
(2007)Specificity to target molecule, high selectivity and sensitivity to release and targeting were achieved using molecularly imprinted polymer (MIP) systems. In this study, propranolol HCl (PHCL) imprinted methacryloylamido ...