Browsing Eczacılık Fakültesi by Title
Now showing items 1404-1423 of 1731
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Synthesis and analgesic activity of some triazoles and triazolothiadiazines
(Elsevier Science Sa, 1999)The synthesis of some triazoles and triazolothiadiazines starting from (5,6,7,8-tetrahydronaphthalen-2-yl)oxyacetic acid is described. The chemical structure of the compounds were elucidated by analytical, IR, H-1 NMR and ... -
Synthesis and analgesic effects of 2-(2-carboxyphenylsulfanyl)-N-(4-substitutedphenyl)acetamide derivatives
(Springer Birkhauser, 2011)This present study was undertaken to synthesize and investigate possible analgesic activities of some 2-(2-carboxyphenylsulfanyl)-N-(4-substitutedphenyl)acetamide derivatives that were designed by combining an analgesic ... -
Synthesis and anti-cancer activity evaluation of new aurone derivatives
(Taylor & Francis LTD, 2015)In this study, we have synthesized 2-[3-or 4-(2-aryl-2-oxoethoxy) arylidene] benzofuran-3-one derivatives (D1-D38) and evaluated their anti-cancer activities. The final compounds were obtained in multistep synthesis reactions ... -
Synthesis and anti-Candida activity of novel 2-hydrazino-1,3-thiazole derivatives
(Pergamon-Elsevier Science LTD, 2013)Eighteen new hydrazino-1,3-thiazole derivatives were evaluated against 8 strains of multi-resistant Candida spp. Introduction of an indolyl moiety linked to the hydrazone function enhanced the in vitro anti-Candida activity, ... -
Synthesis and anti-inflammatory activity of some 1,2,4-triazole derivatives
(Prous Science, Sa, 2007)… -
Synthesis and anti-nociceptive, anti-inflammatory activities of new aroyl propionic acid derivatives including N-acylhydrazone motif
(Springer Birkhauser, 2015)In the present study, new 4-[4-[2-(2-(4-substituted benzylidene)hydrazinyl)-2-oxoethoxy]phenyl]-4-oxobutanoic acid derivatives were synthesized, and their anti-nociceptive and anti-inflammatory activities were investigated. ... -
Synthesis and antibacterial activities of some 1-[2-(substituted pyrrol- 1-yl)ethyl]-2-methyl-5-nitroimidazole derivatives
(Elsevier Masson SAS, 1999)In this study, some 1-[2-(substituted pyrrol-1-yl)ethyl]-2-methyl-5- nitroimidazole derivatives were synthesized by reacting 2-(2-methyl-5-nitro- 1H-imidazolyl)ethylamine dihydrochloride, which was prepared using metronidazole, ... -
Synthesis and antibacterial activity of tert-butyl [1-benzyl-2[(4-aryl-2-thiazolyl)hydrazono]ethyl]carbamate derivatives
(Wiley-V C H Verlag GMBH, 2007)The increasing clinical importance of drug-resistant fungal and bacterial pathogens has lent additional urgency to microbiological research and new antibacterial compound development. For this purpose, new tent-butyl[1-b ... -
Synthesis and antibacterial and antifungal evolution of some ethyl 1- aryloxyacetylamino-5-arylpyrrole-3-carboxylic acid derivatives
(1998)In this study some ethyl 1-aryloxyacetylamino-2methyl-5-aryl-1H-pyrrole- 3-carboxylic acid derivatives were obtained by reacting some aryloxyacetylhydrazide and 1-aryl-3-carbethoxy-1,4-pentadione derivatives. The antibacterial ... -
Synthesis and Anticancer Activities of Some Thiazole Derivatives
(Taylor & Francis LTD, 2009)In this study, 2-substituted 4-[3/4-(4-arylthiazole-2-yl) aminophenyl] thiazole derivatives and 2-[4-[2-substituted 4-methylthiazole-5-yl]thiazole-2-yl] amino-5-arylidenethiazoline-4-one derivatives have been synthesized. ... -
Synthesis and anticancer activity evaluation of N-[4-(2-methylthiazol-4-yl)phenyl]acetamide derivatives containing (benz)azole moiety
(Informa Healthcare, 2014)A new class of novel thiazole-(benz) azole derivatives was synthesized to investigate their anticancer activity. The structure of the compounds was confirmed by IR, H-1-NMR, and MS spectral data and elemental analyses. ... -
Synthesis and Anticancer Activity of New Hydrazide-hydrazoncs and Their Pd(II) Complexes
(Bentham Science Publ LTD, 2019)Background: Hydrazones, one of the important classes of organic molecules, are pharmaceutical agents comprising -CO-NH-N=CH- group in the structure therefore and exhibiting significant biological activity. Methods: ... -
Synthesis and anticancer activity of some 1,2,3-trisubstituted pyrazinobenzimidazole derivatives
(Taylor & Francis LTD, 2014)The synthesis of some new pyrazino[1,2-a]benzimidazole derivatives and investigation of their anticancer activities were aimed in this work. Thus, 2-acetylbenzimidazole was reacted with appropriate alpha-bromoacetophenones ... -
Synthesis and Anticancer Activity of Some 1H-inden-1-one Substituted (Heteroaryl)Acetamide Derivatives
(Bentham Science Publ LTD, 2019)Background: The synthesis of 2-[3/4-((6-substituted-1-oxo-2,3-dihydro-1H-inden-2ylidene) methyl)phenoxy]-N-(heteroaryl)acetamide derivatives and the investigation of their anticancer activity were studied. Methods: ... -
Synthesis and Anticancer Activity of Some 2-[3/4-(2-Substituted Phenyl-2-oxoethoxy)benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one Derivatives
(Bentham Science Publ LTD, 2014)The synthesis of 2-[3/ 4-(2-substituted phenyl-2-oxoethoxy) benzylidene]-6-substituted-2,3-dihydro-1H-inden-1one derivatives and the investigation of their anticancer activity were studied. 2-(3- or 4-Hydroxybenzylidene) ... -
Synthesis and anticancer activity of some bisquinoxaline derivatives
(2011)Mevcut antikanser ajanlara karşı rezistans gelişimi, yeni antikanser ajanlar için bir araştırma alanı yaratmaktadır. Bununla birlikte, normal hücreler üzerinde etki göstermeden ya da en az etkiyle anormal hücrelerin ... -
Synthesis and anticancer activity of some bisquinoxaline derivatives [Bazi biskinoksalin türevlerinin sentezleri ve antikanser aktiviteleri]
(2011)Resistance improvement against the existing anticancer agents creates a research area for new anticancer agents. Nevertheless, it is rather difficult to develop a new agent which can selectively inhibit the proliferation ... -
Synthesis and anticancer activity of some novel benzothiazole-thiazolidine derivatives
(Taylor & Francis LTD, 2018)Sixteen new 2-(benzothiazol-2-ylthio)-N-(3-substituted-4-(3,4-substitutedphenyl)thiazol-2(3H)-ylidene)acetohydrazide derivatives (4a-4p) were synthesized. The structures of the synthesized compounds were elucidated using ... -
Synthesis and anticancer and anti-HIV testing of some pyrazino[1,2-a]benzimidazole derivatives
(2002)In this study, some 1-methylene-2,3-diaryl-1,2-dihydropyrazino[1,2-a]benzimidazole and some 1-(2-arylvinyl)-3-arylpyrazino[1,2-a]benzimidazole derivatives were synthesised. The structure elucidation of the compounds was ... -
Synthesis and Anticandidal Activities of Some Aryl (5-Chloro-Benzofuran-2-yl) Ketoximes
(Bentham Science Publ LTD, 2019)Background: In this study, some aryl (5-chloro-benzofuran-2-yl) ketoximes and their ethers were synthesised to evaluate their antifungal activity against C. albicans, C. glabrata, C. krusei, and C. parapsilosis. Methods: ...