Başlık için Eczacılık Fakültesi listeleme
Toplam kayıt 1731, listelenen: 1632-1651
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Synthesis, antibacterial and antifungal activities of 3-(1,2,4-triazol-3-yl)-4-thiazolidinones
(Taylor & Francis LTD, 2009)A new series of 3-(1,2,4-triazol-3-yl)-4-thiazolidinone derivatives has been synthesized by the reaction of Schiff bases of 3-amino-1,2,4-triazoles with mercaptoacetic acid and 2-mercaptopropionic acid. Their antibacterial ... -
Synthesis, Antibacterial and Antifungal Activities of Some Carbazole Dithiocarbamate Derivatives
(Bentham Science Publ LTD, 2011)In this study, we aimed at the synthesis of new N, N-disubstituted dithiocarbamoic acid, 2-[(9-ethyl-9H-carbazol-3-yl) amino]-2-oxoethyl esters and their antimicrobial evaluations. The chemical structures of the compounds ... -
Synthesis, Antibacterial, Antifungal, Antimycobacterial Activity Evaluation of Novel 1,2,4-triazole Derivatives Bearing 4-Aminophenyl Moiety
(Bentham Science Publ LTD, 2017)Background: In this work, 2-[[5-(4-aminophenyl)-4-(4-substituted phenyl)-4H-1,2,4-triazol- 3-yl] thio]-1-(4-substituted phenyl) ethan-1-one derivatives (1-15) and 2-[[5-(4-aminophenyl)-4-( 4-substituted phenyl)-4H-1,2,4- ... -
Synthesis, anticandidal activity and cytotoxicity of some tetrazole derivatives
(Taylor & Francis LTD, 2014)In this study, 14 different 2-[(1-methyl-1H-tetrazole-5-yl)thio]-1-(phenyl) ethanone derivatives (1-14) were synthesized. The structures of the obtained compounds were elucidated using IR, H-1-NMR, C-13-NMR and FAB(+)-MS ... -
Synthesis, anticandidal activity, and cytotoxicity of some thiazole derivatives with dithiocarbamate side chains
(Scientific Technical Research Council Turkey-Tubitak, 2014)Some thiazole derivatives bearing dithiocarbamic acid esters were synthesized in order to investigate their anticandidal activity and cytotoxicity. The structures of the obtained final compounds (6a-j) were confirmed by ... -
The synthesis, antifungal and apoptotic effects of triazole-oxadiazoles against Candida species
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2018)In search of potent and safe antifungal agents, herein, we report the synthesis, characterization and biological activities of triazole-oxadiazole compounds. The structural verification of the molecules was carried out by ... -
Synthesis, antimicrobial activity and cytotoxicity of novel oxadiazole derivatives
(Taylor & Francis LTD, 2012)In the present study, 5-substituted-1,3,4-oxadiazolin-2-thiones (1a-b) were synthesized via the ring closure reactions of appropriate acid hydrazides with carbon disulphide. N-(Benzothiazol-2-yl)-2-[[5-substituted-1,3,4- ... -
Synthesis, antimicrobial activity and cytotoxicity of some new carbazole derivatives
(Informa Healthcare, 2012)In this work, some N-(9-Ethyl-9H-carbazole-3-yl)-2-(phenoxy) acetamide derivatives were synthesised and evaluated for their antimicrobial activity and cytotoxicity. The structural elucidation of the compounds was performed ... -
Synthesis, Antituberculotic, and Cytotoxic Properties of New Hydrazone Derivatives Bearing Pyrimidine-Alkylsulfanyl Moiety
(Taylor & Francis LTD, 2015)A series of N'-(arylidene)-4-[(pyrimidine-2-yl)thio]butanohydrazide derivatives (3a-3m) has been synthesized and investigated for their antituberculotic and cytotoxic activity. The antitubercular activities of the newly ... -
Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors
(Academic Press Inc Elsevier Science, 2019)The synthesis, characterization and biological evaluation of a series of novel N-substituted phthalazine sulfonamide (5a-1) are disclosed. Phthalazines which are nitrogen-containing heterocyclic compounds are biologically ... -
Synthesis, characterization and antimicrobial activity of a Zn(II) complex with 1-(1H-benzoimidazol-2-yl)-ethanone thiosemicarbazone
(Taylor & Francis LTD, 2008)A new Zn(II) complex with 1-(1H-benzoimidazol-2-yl)-ethanone thiosemicarbazone [Zn(NO(3))(H(2)O)(C(10)H(11)N(5)S)]NO(3) was prepared and characterized by elemental analyses, FT-IR, (1)H NMR spectroscopy, thermogravimetric ... -
Synthesis, characterization and biological evaluation of a novel Cu(II) complex with the mixed ligands 2,6-pyridinedicarboxylic acid and 2-aminopyridine
(Pergamon-Elsevier Science LTD, 2009)A novel bridged binuclear Cu(II) complex with mixed ligands, di-mu-(2-aminopyridine(N,N'))-bis[(2,6-pyridinedicarboxylate)aquacopper(II)] tetrahydrate, formulated as [Cu(mu-ap)(dipic)(H2O)](2)center dot 4H(2)O (1) (dipic ... -
Synthesis, characterization of some transition-metal complexes of a new heptadentate N(5)S(2) Schiff-base ligand and the effects of these metal complexes on U2OS cells cytotoxicity and DNA cleavage activity
(Taylor & Francis LTD, 2008)Metal complexes of a heptadentate N(5)S(2) donor Schiff-base ligand were synthesized by the template reaction between 2,6-bis(2-aminothiophenoxymethyl)pyridine and 2,2 '-bipyridine-6,6'-dicarboxaldehyde in the presence of ... -
Synthesis, Characterization, and Molecular Docking Study of Some Novel Imidazole Derivatives as Potential Antifungal Agents
(Wiley, 2019)The azole pharmacophore is still regarded as a viable lead structure for the synthesis of more effective antifungal agents. In this study, two novel series of imidazole derivatives containing dithiocarbamate (5a-5g) and ... -
Synthesis, Characterization, Antibacterial, Antifungal and Antituberculous Activities of Some Macrocyclic Coordination Compounds of Zn(II), Cd(II) & Hg(II)
(Asian Journal Of Chemistry, 2011)The increasing clinical importance of drug-resistant mycobacterial pathogens has lent additional urgency to microbiological research and I new antimycobacterial compound development. For this purpose, in this study, Zn(II), ... -
Synthesis, crystal structure and biological activity of 1-(1H-benzoimidazol-2-yl)-ethanone thiosemicarbazone and its cobalt complex
(Pergamon-Elsevier Science LTD, 2008)1-(1H-Benzoimidazol-2-yl)-ethanone thiosemicarbazone (H2L) (1) was obtained by the condensation reaction of 2-acetylbenzimidazole, thiosemicarbazide and acetic acid in ethanol. The novel cobalt(III) complex [Co(L)(HL)] 2 ... -
Synthesis, molecular docking analysis and carbonic anhydrase I-II inhibitory evaluation of new sulfonamide derivatives
(NLM (Medline), 2019)New sulfonamide-hydrazone derivatives (3a-3n) were synthesized to evaluate their inhibitory effects on purified human carbonic anhydrase (hCA) I and II. The inhibition profiles of the synthesized compounds on hCA I-II ... -
Synthesis, Molecular Docking Studies, and Antifungal Activity Evaluation of New Benzimidazole-Triazoles as Potential Lanosterol 14 alpha-Demethylase Inhibitors
(Hindawi LTD, 2017)Due to anticandidal importance of azole compounds, a new series of benzimidazole-triazole derivatives(5a-5s) were designed and synthesized as ergosterol inhibitors. Thechemical structures of the target compounds were ... -
Sytheses and antispazmodic effects of some 2-aryl-4,5,6,7-tetrahydro-(1H)-benzimidazoles
(Blackwell Publishing, 2006)… -
Şevketi bostan (Scolymus hispanicus L.) bitkisini kültüre alma ve seleksiyon ıslahı
(2011)Çalışma Asteraceae familyasından tıbbi bir bitki olan şevketi bostan (Scolymus hispanicus L.) bitkisini kültüre alma amacı ile 2006-2009 yılları arasında yürütülmüştür. Bu amaçla, seleksiyon ıslahı ile populasyon ...