Yazar "İşcan, Gökalp" için Eczacılık Fakültesi listeleme
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Essential oils of three species of Heracleum. Anticandidal activity
İşcan, Gökalp; Özek, Temel; Özek, Gülmira; Duran, Ahmet; Başer, K. Hüsnü Can (Springer, 2004)Fruits of Heracleum crenatifolium Boiss., Heracleum sphondylium L subsp. ternatum (Velen.) Brummitt, and Heracleum platytaenium Boiss. (Umbelliferae) were hydrodistilled to obtain essential oils that were then analyzed by ... -
Evaluation of antioxidant and antimicrobial activities of Tamus communis L. ssp. cretica (L.) Kit Tan and its mineral composition [Tamus communis L. ssp. cretica (L.) Kit Tan’ın antioksidan ve antimikrobiyal aktivitelerinin değerlendirilmesi ve mineral kompozisyonu]
Küçükboyaci, N.; Turan, Dural, N. N.; Köroğlu, A.; İşcan, Gökalp; Aydın, Ahmet (Turkish Pharmacists Association, 2015)The aim of the present work was to examine antioxidant and antimicrobial properties of Tamus communis L. ssp. cretica (L.) Kit Tan (Dioscoreaceae). The applied methods for the antioxidant activity of aqueous extract from ... -
Microbial Transformation of beta-Phellandrene
İşcan, Gökalp; Kinmer, N.; Demirci, Fatih; Başer, K. Hüsnü Can (Georg Thieme Verlag Kg, 2011)… -
Microbiological safety controls of selected hydrosols and their volatile compounds [Bazi{dotless} yag alti{dotless} sulari{dotless}ni{dotless}n uçucu bileşikleri ve mikrobiyal kontrolleri]
There are only a few scientific studies on the analysis, quality control and standardization of hydrosols of commonly used aromatic plants in Turkey. In order to fill this gap, hydrosols of commercially important plants ... -
Preparation of some pyrazoline derivatives and evaluation of their antifungal activities
Özdemir, Ahmet; Turan, Gülhan; Kaplancıklı, Zafer Asım; Revıal, Gilbert; Demirci, Fatih; İşcan, Gökalp (Informa Healthcare, 2010)The synthesis of a new series of 1-[( benzazole-2-yl)thioacetyl]-3,5-diaryl-2-pyrazoline derivatives was obtained by reacting 1-( chloroacetyl)-3,5-diaryl-pyrazolines with 2-mercaptobenzimidazole/benzoxazole/benzothiazole. ... -
Stachys citrina subsp. citrina Uçucu Yağının Kimyasal Karakterizasyonu ve Antimikrobiyal Değerlendirilmesi
Türkiye için endemik bir tür olan Stachys citrina Boiss. et Heldr. subsp. citrina (Lamiaceae) bitkisinin çiçekli toprak üstü kısımlarından su distilasyonu ile elde edilen uçucu yağın GC-FID ve GCMS sistemleri ile eş zamanlı ... -
Studies on hydrazone derivatives as antifungal agents
Özdemir, Ahmet; Turan, Gülhan; Kaplancıklı, Zafer Asım; Demirci, Fatih; İşcan, Gökalp (Taylor & Francis LTD, 2008)The increasing clinical importance of drug-resistant fungal pathogens has urged additional need to fungal research and new antifungal compound development. For this purpose, some N-(1-benzyl-2-phenylethylidene)-N'-[4-(ar ... -
Synthesis and anticandidal activity of new triazolothiadiazine derivatives
Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım; Turan, Gülhan; Özdemir, Ahmet; İşcan, Gökalp; Akalın Çiftçi, Gülsen; Yıldırım, Şafak Ulusoylar (Elsevier France-Editions Scientifiques Medicales Elsevier, 2011)New triazolothiadiazine derivatives were synthesized via the ring closure reaction of 4-amino-5-substituted-2,4-dihydro-3H-1,2,4-triazol-3-thiones with phenacyl bromides. The compounds were tested in vitro against various ... -
Synthesis and antifungal activity of some thiazolylhydrazone derivatives
Özdemir, Ahmet; Turan, Gülhan; Kaplancıklı, Zafer Asım; Demirci, Fatih; İşcan, Gökalp (Prous Science, Sa, 2007)… -
Synthesis and antimicrobial activities of some imidazole substituted indoles
Benkli, Kadriye; Demirayak, Şeref; Gündoğdu-Karaburun, N; Kiraz, N; İşcan, Gökalp; Uçucu, U (Council Scientific & Industrial Res, 2004)The compounds 1-substituted 2-(imidazol-1-yl)-3-(4,5-diarylimidazol-2-yl) indoles 2, I-substituted 2-(imidazol-1-yl)3-(phenanthro[9,10-d]imidazol-2-yl)indoles 3 and 1-substituted 2-(imidazol-1-yl)-3-(benzimidazol-2-yl)indoles ... -
Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents
Erguc, Ali; Altıntop, Mehlika Dilek; Atlı Eklioğlu, Özlem; Sever, Belgin; İşcan, Gökalp; Gormus, Gözde; Özdemir, Ahmet (Bentham Science Publ LTD, 2018)Background: In medicinal chemistry, thiazoles have gained great importance in anti-fungal and anticancer drug design and development. Objectives: The aim of this study was to synthesize new quinoline-based thiazolyl hydrazone ... -
Synthesis and Biological Evaluation of some Amide Derivatives Bearing Benzothiazole and Piperidine Moieties as Antimicrobial Agents
Altıntop, Mehlika Dilek; Özdemir, Ahmet; Kaplancıklı, Zafer Asım; Turan, Gülhan; İşcan, Gökalp; Çiftçi, Gülsen Akalın (Bentham Science Publ LTD, 2013)In this study, N-(benzothiazol-2-yl)-2-(piperidin-1-yl)acetamide derivatives (1-24) were obtained by the reaction of 2-chloro-N-(benzothiazole-2-yl)acetamides with piperidine derivatives. The structures of the compounds ... -
Synthesis and biological evaluation of some hydrazone derivatives as new anticandidal and anticancer agents
Altıntop, Mehlika Dilek; Özdemir, Ahmet; Turan, Gülhan; Ilgın, Sinem; Atlı Eklioğlu, Özlem; İşcan, Gökalp; Kaplancıklı, Zafer Asım (Elsevier France-Editions Scientifiques Medicales Elsevier, 2012)New hydrazone derivatives were synthesized via the nucleophilic addition-elimination reaction of 2-[(1-methyl-1H-tetrazol-5-yl]thio)]acetohydrazide with aromatic aldehydes/ketones. The compounds were tested in vitro against ... -
Synthesis and the selective antifungal activity of 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives
Özdemir, Ahmet; Turan, Gülhan; Kaplancıklı, Zafer Asım; İşcan, Gökalp; Khan, Shabana I.; Demirci, Fatih (Elsevier France-Editions Scientifiques Medicales Elsevier, 2010)Even though there are new classes of compounds now frequently used in treatment of fungal infections, the density of deeply invasive candidiasis has increased at least 10-fold during the past decade. Furthermore, many ... -
Synthesis of some dithiocarbamate derivatives and their antimicrobial activity
Kaplancıklı, Zafer Asım; Turan, Gülhan; Revial, G; İşcan, Gökalp (Taylor & Francis LTD, 2004)Some new, 2-[(N-substituted aminothiocarbonylthio)acetyl]aminothiazole, N-substituted aminothiocarbonylthioacetylaminodiphenylmethane and 9-[(N-substituted aminothiocarbonylthio)acetyl]aminofluorene derivatives were ... -
Synthesis of Some Novel Triazole Derivatives and Investigation of Their Antimicrobial Activities
Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım; Turan, Gülhan; Özdemir, Ahmet; Demirci, Fatih; İşcan, Gökalp; Revial, Gilbert (Taylor & Francis Inc, 2011)[image omitted] The aim of this study is to synthesize new triazole derivatives and investigate their antimicrobial activities. 4-Amino-5-(2-cyclohexylethyl)-3-[N-(benzothiazole-2-yl)acetamido]thio-4H-1,2,4-triazole and ... -
Synthesis, anticandidal activity and cytotoxicity of some tetrazole derivatives
Kaplancıklı, Zafer Asım; Yurttaş, Leyla; Özdemir, Ahmet; Turan, Gülhan; İşcan, Gökalp; Akalın Çiftçi, Gülsen; Abu Mohsen, Usama (Taylor & Francis LTD, 2014)In this study, 14 different 2-[(1-methyl-1H-tetrazole-5-yl)thio]-1-(phenyl) ethanone derivatives (1-14) were synthesized. The structures of the obtained compounds were elucidated using IR, H-1-NMR, C-13-NMR and FAB(+)-MS ... -
Volatile metabolites of endophytic fungi isolated from Brazilian Barbatimão tree
İşcan, Gökalp (2017)Endofitik funguslar bitkilerle ortaklaşa bir yaşam sürdürmekle birlikte, onların biyotik ve abiyotik stres koşullarına karşı dirençlerini arttırmaktadırlar. Endofitik fungusların biyoçeşitliliği çok fazladır ve birçok ... -
Volatile Oil Composition and Biological Activity of Achillea Biebersteinh Afan. and Achillea Teretifolia Willd
Köse, Yavuz Bülent; Demirci, Betül; İşcan, Gökalp (Parlar Scientific Publications (PSP), 2017)The genus Achillea L. (Asteraceae) is widely distributed in Turkey and used as folk remedies for their several biological effects. In this study hydro distilled essential oils of Achillea biebersteinii and Achillea teretifolia ... -
Volatile oil composition and biological activity of Achillea biebersteinii afan. and Achillea teretifolia willd.
Köse, Yavuz Bülent; Demirci, Betül; İşcan, Gökalp (Parlar Scientific Publications, 2017)The genus Achillea L. (Asteraceae) is widely distributed in Turkey and used as folk remedies for their several biological effects. In this study hydro-distilled essential oils of Achillea biebersteinii and Achillea teretifolia ...