Browsing Eczacılık Fakültesi by Author "Öztürk, Ahmet Alper"
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Cefaclor monohydrate loaded microemulsion formulation for topical application: Characterization with new developed UPLC method and stability study
Öztürk, Ahmet Alper; Güven, Umay Merve (Marmara University, 2019)The purpose of this study was to formulate Cefaclor monohydrate (CEF) loaded microemulsion formulations with the help of pseudo-ternary phase diagrams for topical application. Additionally, in this study also a new ... -
Development of nano-sized ketoprofen lysine incorporated Eudragit (R) S100 nanomedicine by double emulsion solvent evaporation and in vitro characterization
Öztürk, Ahmet Alper; Çınar, Nur İlge; Yenilmez, Evrim (Journal Pharmacy & Pharmacognosy Research-Jppres, 2019)Context: Pain has a very important effect on the biological, psychological, sociological and economic situation of a patient. Nanoparticles (NPs) are being extensively investigated as drug delivery systems worldwide for ... -
Dexketoprofen trometamol-loaded eudragit® rl 100 nanoparticle formulation, characterization and release kinetics
Öztürk, Ahmet Alper; Yenilmez, Evrim; Yazan, Yasemin (İstanbul Medipol University, 2019)Development and in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized and controlled release drug delivery system was aimed in this study. DT-loaded Eudragit® RL 100 polymeric nanoparticles were prepared ... -
Dexketoprofen Trometamol-Loaded Kollidon (R) SR and Eudragit (R) RS 100 Polymeric Nanoparticles: Formulation and In Vitro-In Vivo Evaluation
Öztürk, Ahmet Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (Colegio Farmaceuticos Provincia De Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon (R) SR (KSR) and Eudragit (R) RS 100 (ERS) ... -
Dexketoprofen trometamol-loaded kollidon® SR and eudragit® RS 100 polymeric nanoparticles: Formulation and in vitro-in vivo evaluation
Öztürk, Ahmet Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon® SR (KSR) and Eudragit® RS 100 (ERS) ... -
Dexketoprofen trometamol-loaded poly-lactic-co-glycolic acid (PLGA) nanoparticles: Preparation, in vitro characterization and cyctotoxity
Öztürk, Ahmet Alper; Banderas, Lucia Martin; Otero, Maria D. Cayero; Yenilmez, Evrim; Senal, Behiye; Yazan, Yasemin (Pharmacotherapy Group, 2019)Purpose: To design, formulate and characterize sustained-release formulations of dexketoprofen trometamol (DT) nanoparticles (NPs) Methods: Dexketoprofen trometamol (DT)-loaded poly(lactic-co-glycolic acid) (PLGA) NPs were ... -
Effects of Different Derivatives of Eudragit Polymer on Entrapment Efficiency, In Vitro Dissolution, Release Kinetics and Cell Viability Results on Extended Release Flurbiprofen Loaded Nanomedicines
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim; Şenel, Behiye (Colegio Farmaceuticos Provincia De Buenos Aires, 2018)The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ... -
Effects of different derivatives of eudragit polymer on entrapment efficiency, in vitro dissolution, release kinetics and cell viability results on extended release flurbiprofen loaded nanomedicines
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim; Şenel, Behiye (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ... -
Flurbiprofen loaded gel based topical delivery system: Formulation and in vitro characterization with new developed UPLC method
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim (İstanbul Medipol University, 2018)Objective: The purpose of this study was to formulate flurbiprofen (FLB) loaded methylcellulose (MC), hydroxypropyl methylcellulose (HPMC) and Carbopol®940 (C-940) based gel formulations with the help of dispersion method ... -
Influence of glyceryl behenate, tripalmitin and stearic acid on the properties of clarithromycin incorporated solid lipid nanoparticles (SLNs): Formulation, characterization, antibacterial activity and cytotoxicity
Öztürk, Ahmet Alper; Aygül, A.; Şenel, B. (Editions de Sante, 2019)Clarithromycin (CLR) is a macrolide derivative which is included in BCS class 2 with low oral bioavailability. Solid lipid nanoparticles (SLNs) have been studied by many researchers for drug application and are very popular ... -
New Approach to Hypertension Treatment: Carvediol-Loaded PLGA Nanoparticles, Preparation, In Vitro Characterization and Gastrointestinal Stability
Öztürk, Ahmet Alper; Martin Banderas, Lucia; Cayero Otero, Maria D.; Yenilmez, Evrim; Yazan, Yasemin (Colegio Farmaceuticos Provincia De Buenos Aires, 2018)Carvedilol (CVL) has advantages over the first generation of beta-blockers in patients with heart failure due to its properties of reducing cardiovascular morbidity and mortality. On the other hand, CVL has a short half-life ... -
New approach to hypertension treatment: Carvediol-loaded PLGA nanoparticles, preparation, in vitro characterization and gastrointestinal stability
Öztürk, Ahmet Alper; Martin, Banderas, L.; Cayero Otero, Maria D.; Yenilmez, Evrim; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)Carvedilol (CVL) has advantages over the first generation of ß-blockers in patients with heart failure due to its properties of reducing cardiovascular morbidity and mortality. On the other hand, CVL has a short half-life ... -
Supervised Machine Learning Algorithms for Evaluation of Solid Lipid Nanoparticles and Particle Size
Öztürk, Ahmet Alper; Gündüz, A. Bilge; Özışık, Özan (Bentham Science Publ LTD, 2018)Aims and Objectives: Solid Lipid Nanoparticles (SLNs) are pharmaceutical delivery systems that have advantages such as controlled drug release, long-term stability etc. Particle Size (PS) is one of the important criteria ...