Browsing Eczacılık Fakültesi by Author "Adams, Erwin"
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Development of a CD-MEKC method for investigating the metabolism of tamoxifen by flavin-containing monooxygenases and the inhibitory effects of methimazole, nicotine and DMXAA
Yeniceli, Duygu; Deng, Xiaolan; Adams, Erwin; Ak, Dilek; Van Schepdael, Ann (Wiley-Blackwell, 2013)A selective and low-cost CD-MEKC method under acidic conditions was developed for investigating the N-oxygenation of tamoxifen (TAM) by flavin-containing monooxygenases (FMOs). The inhibitory effects of methimazole (MMI), ... -
A sensitive capillary LC-UV method for the simultaneous analysis of olanzapine, chlorpromazine and their FMO-mediated N-oxidation products in brain microdialysates
Hendrickx, Stijn; Uğur, Duygu Yeniceli; Yılmaz, Işıl Tan; Şener, Erol; Van Schepdael, Ann; Adams, Erwin; Cabooter, Deirdre (Elsevier Science BV, 2017)A specific and sensitive capillary liquid chromatography-ultraviolet detection (cap-LC-UV) method in combination with a micro-extraction by packed sorbent (MEPS) sample clean-up procedure has been developed and validated ...