Yazar "Kırımlıoğlu, Gülsel Yurtdaş" için Eczacılık Fakültesi listeleme
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Gamma-aminobutyric acid loaded halloysite nanotubes and in vitro-in vivo evaluation for brain delivery
Kırımlıoğlu, Gülsel Yurtdaş; Yazan, Yasemin; Erol, Kevser; Unel, Çiğdem Cengelli (Elsevier Science BV, 2015)Gamma-aminobutyric acid (GABA) is a key neurotransmitter where it usually inhibits impulse transmission. GABA release blockage or postsynaptic reaction were determined to provoke epileptic convulsions. The aim of the present ... -
In vitro/in vivo evaluation of gamma-aminobutyric acid-loaded N,N-dimethylacrylamide-based pegylated polymeric nanoparticles for brain delivery to treat epilepsy
Kırımlıoğlu, Gülsel Yurtdaş; Menceloğlu, Yusuf; Erol, Kevser; Yazan, Yasemin (Taylor & Francis LTD, 2016)Objectives of this study were the delivery of gamma aminobutyric acid (GABA) into the brain by means of developing brain targeted, nanosized, non-toxic and biocompatible polymeric nanoparticles, and investigating their ... -
Ornidazole Incorporated Chitosan Nanoparticles for Ocular Application
Başaran, Ebru; Şenel, Behiye; Kırımlıoğlu, Gülsel Yurtdaş; Güven, Umay Merve; Yazan, Yasemin (Colegio Farmaceuticos Provincia De Buenos Aires, 2015)Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ... -
Ornidazole incorporated chitosan nanoparticles for ocular application
Başaran, Ebru; Şenel, Behiye; Kırımlıoğlu, Gülsel Yurtdaş; Güven, Umay Merve; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2015)Considering the low ocular bioavailability of conventional formulations used for ocular bacterial infection treatment, there is a need for developing efficient modern drug delivery systems. Main attempt in this study was ... -
Preparation and in vitro characterization of a fluconazole loaded chitosan particulate system
Kırımlıoğlu, Gülsel Yurtdaş; Yenilmez, Evrim; Başaran, Ebru; Yazan, Yasemin (İstanbul Medipol University, 2019)In the present study fluconazole (FZ) was successfully incorporated into cationic chitosan nanoparticles prepared by spray-drying method aiming dermal delivery. Particle size and zeta potential measurements, drug content, ... -
Preparation, Characterization and In Vitro Evaluation of Dirithromycin Loaded Eudragit (R) RS 100 Nanoparticles for Topical Application
Yenilmez, Evrim; Kırımlıoğlu, Gülsel Yurtdaş; Şenel, Behiye; Başaran, Ebru (Colegio Farmaceuticos Provincia De Buenos Aires, 2017)The purpose of the study was to formulate dirithromycin (DR) loaded Eudragit (R) RS 100 (ERS) nanoparticles for topical application and to analyze the physical and chemical characteristics and in vitro toxicity of the ...