Yazar "Kıran, İsmail" için Eczacılık Fakültesi listeleme
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Biotransformation of ?-cedrol and caryophyllene oxide by the fungus Neurospora crassa
Kıran, İsmail; Durceylan, Zeynep; Kırımer, Neşe; Başer, K. Hüsnü Can; Noma, Yoshiaki; Demirci, Fatih (2010)Incubation of ?-cedrol and caryophyllene oxide with Neurospora crassa afforded 12ß-hydroxy cedrol, 10?-hydroxy cedrol, and 3?-hydroxy cedrol, and 12ß-hydroxy caryophyllene oxide as major metabolites, respectively. The ... -
Biotransformation of abietic acid by fungi and biological evaluation of its metabolites
Özşen, Özge; Kıran, İsmail; Dağ, İlknur; Atlı Eklioğlu, Özlem; Çiftçi, Gülsen Akalın; Demirci, Fatih (Elsevier Sci LTD, 2017)Biotransformation of abietic acid was carried out initially using 28 different microbial strains. Among the evaluated, Mucor ramannianus produced a known metabolite namely 2 alpha-hydroxy-dehydroabietic acid whereas ... -
Biotransformation of alpha-Cedrol and Caryophyllene Oxide by the Fungus Neurospora crassa
Kıran, İsmail; Durceylan, Zeynep; Kırımer, Neşe; Başer, K. Hüsnü Can; Noma, Yoshiaki; Demirci, Fatih (Natural Products Inc, 2010)Incubation of a-cedrol and caryophyllene oxide with Neurospora crassa afforded 12 beta-hydroxy cedrol, 10 alpha-hydroxy cedrol, and 3 beta-hydroxy cedrol, and 12 beta-hydroxy caryophyllene oxide as major metabolites, ... -
Cytotoxic, Antiproliferative and Apoptotic Effects of Perillyl Alcohol and Its Biotransformation Metabolite on A549 and HepG2 Cancer Cell Lines
Oturanel, Ceren E.; Kıran, İsmail; Özşen, Özge; Çiftçi, Gülsen Akalın; Atlı Eklioğlu, Özlem (Bentham Science Publ LTD, 2017)Background: A monoterpene, perillyl alcohol, has attracted attention in medicinal chemistry since it exhibited chemo-preventive and therapeutic properties against a variety of cancers. Objective: In the present work, it ... -
Microbial Transformations of Isophorone by Alternaria alternata and Neurospora crassa
Kıran, İsmail; Özşen, Özge; Çelik, Turgay; İlhan, Semra; Gürsu, Bukay Yenice; Demirci, Fatih (Natural Products Inc, 2013)Isophorone (3,5,5-trimethyl-2-cyclohexen-1-one), a monoterpene, and the structurally related 1,8-cineole and camphor, have demonstrated a protective effect against cancer, biological activity against a variety of microorganisms, ... -
Microbial transformations of isophorone by Alternaria alternate and Neurospora crassa
Isophorone (3,5,5-trimethyl-2-cyclohexen-1-one), a monoterpene, and the structurally related 1,8-cineole and camphor, have demonstrated a protective effect against cancer, biological activity against a variety of microorganisms, ...