Kurum Yazarı "Benkli, Kadriye" Eczacılık Fakültesi İçin Listeleme
-
Antibacterial and antifungal activities of some trimethoprim salts
Tunalı, Yağmur; Karaca, Hülya; İşcan, Gökalp; Demirci, Fatih; Benkli, Kadriye (Birkhauser Boston Inc, 2012)In this study, the antimicrobial activities of Trimethoprim (1), Trimethoprim + Maleic acid (2), Trimethoprim + Oxalic acid dihydrate (3), and Trimethoprim + trans-1,2-Cyclohexanedicarboxylic acid (4) were investigated for ... -
Apoptotic effects of dipyrido [3,2-a:2 ',3 '-c] phenazine (dppz) Au(III) complex against diethylnitrosamine/phenobarbital induced experimental hepatocarcinogenesis in rats
Tekin, Neslihan; Üstüner, Mehmet C.; Akyüz, Fahrettin; Özbayer, Cansu S.; Aydın, Özlem; Benkli, Kadriye; Özden, Hilmi (Springer, 2014)We evaluated the effects of dipyrido [3,2-a:2',3'-c] phenazine (dppz) Au(III) complex ([Au(dppz)Cl-2]Cl) on apoptosis during chemically induced hepatocellular carcinoma. 48 male Spraque-Dawley rats were divided into six ... -
Cytotoxic and genotoxic effects of [Ru(phi)(3)](2+) evaluated by Ames/Salmonella and MTT methods
Benkli, Kadriye; Tunalı, Yağmur; Cantürk, Zerrin; Artagan, öge; Alanyali, Filiz (Elsevier France-Editions Scientifiques Medicales Elsevier, 2009)In this work, we synthesized and evaluated the cytotoxic effect of [Ru(phi)(3)](2+), on rat C6 glioma cell line. Cell viability was determined by assay with 3-(4-5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide ... -
Designing of the new antithrombotic and also anticancer gold complexes
Benkli, Kadriye (Pergamon-Elsevier Science LTD, 2016)… -
The effects of some phenanthroline ruthenium (II) complexes on a549 cell proliferation
Ruthenium (II) komplekslerinin DNA bağlanması He ilgili olan yüksek antitumor aktiviteleri nedeni He bu bileşikler son yıllarda araştırmacıların yoğun ilgisini çekmektedir. Bu çalismada imidazo[4,5-f][ 1,10]fenantrolin ... -
The effects of some phenanthroline ruthenium (II) complexes on A549 cell proliferation [Bazi{dotless} fenantrolin rutenyum (II) komplekslerinin a549 hücre çogalmasi{dotless} üzerine etkileri]
In recent years, ruthenium (II) complexes have increasingly attracted the interest of researchers because of their high antitumor activities that are usually related to DNA binding. Here, we synthesized two ruthenium (II) ... -
Inhibition of C6 Glioma Cell Proliferation by Au(III) and Pt(II) Complexes of 1,10-Phenanthroline-5,6-dione
Dikmen, Miriş; Benkli, Kadriye; Öztürk, Yusuf (Asian Journal Of Chemistry, 2011)In this study, we studied the antiproliferative effecs of Au(III) and Pt(II) metal complexes of 1,10-phenanthroline-5,6-dione and cisplatin on rat glioma C6 cells. The antiproliferative effects were evaluated by MTT ... -
Modification of intracellular free calcium in cultured F2408 embryo fibroblasts by 3-sub substituted-2-thiohydantoin derivatives
Seller, Zerrin; Benkli, Kadriye; Akalın, G; Kaplancıklı, Zafer Asım (Wiley, 2004)3-substituted-2-thiohydantoin derivatives were synthesized and their Structures elucidated by IR, H-1-NMR spectroscopy and elemental analysis. The cytotoxicity of the 2-thiohydantoin derivatives to rat embryo fibroblasts ... -
Production of ?-terpineol from ?-pinene
?-Terpineol is a monoterpene alcohol used as a fragrance material in perfumery industry and for the production of some volatile compounds. Several techniques have been described in the literature for its synthesis. These ... -
Some 1-substituted 3-aryl-1,4-dihydro-1,2,4-triazino[4,3-a]- benzimidazoles and their vasodilatory activities
Demirayak, Şeref; Benkli, Kadriye; Karaburun, Ahmet Çağrı (Societa Chimica Italiana, 1997)In this study, some 1-substituted 3-aryl-1,4-dihydro-1,2,4- triazino[4,3-a]benzimidazole derivatives were synthesized, their structures were elucidated, and their vasodilatory activities were examined. It was found that ... -
Studies on the synthesis of some new antipyrine derivatives
Some new 4-(4, 5-diarylimidazole-2-yl) antipyrine, 4-(5-substituted benzimidazole-2-yl) antipyrine and 4-(phenantroimidazole-2-yl) antipyrine derivatives were synthesised. The structure elucidations of the compounds were ... -
Synthesis and antifungal activities of some aryl (3-methyl-benzofuran-2-yl) ketoximes
Benkli, Kadriye; Gündoğdu-Karaburun, N; Karaburun, Ahmet Çağrı; Uçucu, Ümit; Demirayak, Şeref; Kiraz, N (Pharmaceutical Society Korea, 2003)In this study, some aryl (3-methyl-benzofuran-2-yl) ketoximes and their. ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1-NMR, MASS spectroscopy and elemental analyses. ... -
Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes
Gündoğdu-Karaburun, Nalan; Benkli, Kadriye; Tunalı, Yağmur; Uçucu, Ümit; Demirayak, Şeref (Elsevier France-Editions Scientifiques Medicales Elsevier, 2006)In this study, some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketones, aryl (3-methyl-benzofuran-2-yl) ketoximes and aryl [3(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketoximes were synthesised ... -
Synthesis and antifungal activities of some aryl(benzofuran-2-yl)ketoximes
Demirayak, Şeref; Uçucu, Ümit; Benkli, Kadriye; Gündoğdu-Karaburun, Nalan; Karaburun, Ahmet Çağrı; Akar, D; Kiraz, N (Elsevier Science Sa, 2002)In this study, some aryl(benzofuran-2-yl)ketoximes and their ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1 NMR and mass spectroscopic data and elemental analyses ... -
Synthesis and antimicrobial activities of some 3-arylamino-5-[2-(substituted 1-imidazolyl)ethyl]-1,2,4-triazole derivatives
Demirayak, Şeref; Benkli, Kadriye; Güven, Kıymet (Elsevier Masson SAS, 2000)In this study, some 3-arylamino-5-[2-(substituted imidazol-1-yl or benzimidazol-1-yl)ethyl]-1,2,4-triazole derivatives were synthesised by reacting 3-(substituted imidazol-1-yl)propionyl hydrazides, with S-methyl-N'-aryl ... -
Synthesis and antimicrobial activities of some imidazole substituted indoles
Benkli, Kadriye; Demirayak, Şeref; Gündoğdu-Karaburun, N; Kiraz, N; İşcan, Gökalp; Uçucu, U (Council Scientific & Industrial Res, 2004)The compounds 1-substituted 2-(imidazol-1-yl)-3-(4,5-diarylimidazol-2-yl) indoles 2, I-substituted 2-(imidazol-1-yl)3-(phenanthro[9,10-d]imidazol-2-yl)indoles 3 and 1-substituted 2-(imidazol-1-yl)-3-(benzimidazol-2-yl)indoles ... -
Synthesis and antimicrobial activities of some new nitroimidazole derivatives
Benkli, Kadriye; Karaburun, AC; Gündoğdu-Karaburun, N; Demirayak, Şeref; Güven, K (Pharmaceutical Society Korea, 2003)In this study, some new nitroimidazole derivatives were obtained from 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylamine dihydrochloride (4) and 1-(2-bromoethyl)-2-methyl-5-nitroimidazole (5), which were prepared using ... -
Synthesis and antituberculosis activity of new thiazolylhydrazone derivatives
Turan, Gülhan; Özdemir, Ahmet; Kaplancıklı, Zafer Asım; Benkli, Kadriye; Chevallet, Pierre; Akalın Çiftçi, Gülsen (Elsevier France-Editions Scientifiques Medicales Elsevier, 2008)The increasing clinical importance of drug-resistant mycobacterial pathogens has lent additional urgency to microbiological research and new antimycobacterial compound development. For this purpose, new thiazolylhydrazone ... -
Synthesis and characterization of a new macrocyclic ligand and its copper (II), cadmium (II), and lead (II) complexes: Genotoxic activity of these complexes in cultured human lymphocytes
Beynek, Nesrin; Uluçam, Gühergül; Tüylü, Berrin; Sivas, Hülya; Benkli, Kadriye (Taylor & Francis Inc, 2007)A new macrocyclic ligand 1,1'-bis(bis-(6,6'-oxymethylenyl-2,2'-bipyridine) binaphthyl, (L), and its complexes CuL(ClO4)(2), CuL(NO3)(2,) 3H(2)O, CdL(ClO4)(2), and PbL(ClO4)(2) have been synthesized and characterized on the ... -
Synthesis and characterization of new binaphthyl-linked phenanthroline-, bipyridine-, or pyridine-derived ligands, and the study of their cytotoxic activity
In the present work, we describe the synthesis and characterization of five new versatile acyclic or macrocyclic ligands containing binaphthyl-linked pyridine, bipyridine, or phenanthroline groups in their framework (see ...