Konu "Thiosemicarbazone" için Eczacılık Fakültesi listeleme
Toplam kayıt 6, listelenen: 1-6
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Design, synthesis and in vitro evaluation of new thiosemicarbazone derivatives as potential anticancer agents
(Marmara University, 2019)Thiosemicarbazones play a pivotal role as potential therapeutic agents for the management of lung cancer. 4-(4-Cyanophenyl)-1-[(5-arylfuran-2-yl)methylene]thiosemicarbazides (1-10) were obtained via the reaction of ... -
Synthesis and biological evaluation of new naphthalene substituted thiosemicarbazone derivatives as potent antifungal and anticancer agents
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)New thiosemicarbazone derivatives (1-10) were obtained via the reaction of 4-(naphthalen-1-yl)thiosemicarbazide with fluoro-substituted aromatic aldehydes. The synthesized compounds were evaluated for their in vitro ... -
Synthesis and Biological Evaluation of New Thiosemicarbazone Derivative Schiff Bases as Monoamine Oxidase Inhibitory Agents
(MDPI, 2018)Twenty-six novel thiosemicarbazone derivative B1-B26 were synthesized via condensation reactions between the corresponding thiosemicarbazides and aldehydes. The chemical characterization of the compounds was carried out ... -
Synthesis and evaluation of naphthalene-based thiosemicarbazone derivatives as new anticancer agents against LNCaP prostate cancer cells
(Taylor & Francis LTD, 2016)Fourteen new naphthalene-based thiosemicarbazone derivatives were designed as anticancer agents against LNCaP human prostate cancer cells and synthesized. MTT assay indicated that compounds 6, 8 and 11 exhibited inhibitory ... -
Synthesis and Evaluation of New Benzodioxole-Based Thiosemicarbazone Derivatives as Potential Antitumor Agents
(MDPI, 2016)New benzodioxole-based thiosemicarbazone derivatives were synthesized and evaluated for their cytotoxic effects on A549 human lung adenocarcinoma, C6 rat glioma and NIH/3T3 mouse embryonic fibroblast cells. In order to ... -
Synthesis, crystal structure and biological activity of 1-(1H-benzoimidazol-2-yl)-ethanone thiosemicarbazone and its cobalt complex
(Pergamon-Elsevier Science LTD, 2008)1-(1H-Benzoimidazol-2-yl)-ethanone thiosemicarbazone (H2L) (1) was obtained by the condensation reaction of 2-acetylbenzimidazole, thiosemicarbazide and acetic acid in ethanol. The novel cobalt(III) complex [Co(L)(HL)] 2 ...