Yazar "Ak, Dilek" için Makale Koleksiyonu listeleme
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Capillary electrophcretic behaviour and determination of enoxacin in pharmaceutical formulation and human serum
Tunçel, Muzaffer; Ak, Dilek; Pentürk, Z.; Özkan, S. A. (1998)Enoxacin [ENX] is a synthetic broad spectrum antibiotic, which belongs to the fluoroquinolone's family. In this study, a capillary electrophoretic method with UV detection was described for the determination of ENX in ... -
Development of a CD-MEKC method for investigating the metabolism of tamoxifen by flavin-containing monooxygenases and the inhibitory effects of methimazole, nicotine and DMXAA
Yeniceli, Duygu; Deng, Xiaolan; Adams, Erwin; Ak, Dilek; Van Schepdael, Ann (Wiley-Blackwell, 2013)A selective and low-cost CD-MEKC method under acidic conditions was developed for investigating the N-oxygenation of tamoxifen (TAM) by flavin-containing monooxygenases (FMOs). The inhibitory effects of methimazole (MMI), ... -
Isolation of peptide transport system-6 from brain endothelial cells: therapeutic effects with antisense inhibition in Alzheimer and stroke models
Ak, Dilek; Kumar, Vijaya B.; Ryerse, Jan S.; Farr, Susan A.; Verma, Şulekha; Nonaka, Naoko; Banks, William A. (Sage Publications Inc, 2009)By isolating for the first time ever a peptide transporter from the blood-brain barrier (BBB) and developing an antisense that selectively targets the brain-to-blood efflux component, we were able to deliver a therapeutic ...