Kurum Yazarı "İşcan, Gökalp" PubMed İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Antibacterial profiling of abietane-type diterpenoids
Helfenstein, Andreas; Vahermo, Mikko; Nawrot, Dorota A.; Demirci, Fatih; İşcan, Gökalp; Krogerus, Sara; Tammela, Paivi (Pergamon-Elsevier Science LTD, 2017)Abietic and dehydroabietic acid are interesting diterpenes with a highly diverse repertoire of associated bioactivities. They have, among others, shown antibacterial and antifungal activity, potentially valuable in the ... -
Antibacterial, anticandidal and antioxidant properties of Tanacetum argenteum (Lam.) Willd. subsp flabellifolium (Boiss. & Heldr.) grierson
Köse, Yavuz Bülent; İşcan, Gökalp; Göğer, Fatih; Demirci, Betül; Elmaci, Ceren (University Karachi, 2017)In the present study hydrodistilled essential oil and total methanol extracts of Tanacetum argenteum subsp. flabellifolium have been evaluated for their antimicrobial and antioxidant effects. The chemical composition of ... -
Antibacterial, anticandidal and antioxidant properties of Tanacetum argenteum (Lam.) willd. subsp. flabellifolium (Boiss. & Heldr.) grierson
Köse, Yavuz Bülent; İşcan, Gökalp; Göğer, Fatih; Demirci, Betül; Elmaci, C. (Pakistan Journal of Pharmaceutical Sciences, 2017)In the present study hydrodistilled essential oil and total methanol extracts of Tanacetum argenteum subsp. flabellifolium have been evaluated for their antimicrobial and antioxidant effects. The chemical composition of ... -
Anticandidal Activity of the Essential Oil of Nepeta transcaucasica Grossh.
İşcan, Gökalp; Köse, Yavuz Bülent; Demirci, Betül; Başer, K. Hüsnü Can (Wiley-Blackwell, 2011)Hydrodistallation of the aerial parts of Nepeta transcaucasica Grossh. (Lamiaceae), collected in Agri, Dogubayazit Province, afforded an essential oil that was characterized by GC and GC/MS analyses. Twenty-seven compounds, ... -
Anticandidal Effects of Thymoquinone: Mode of Action Determined by Transmission Electron Microscopy (TEM)
İşcan, Gökalp; İşcan, Arzu; Demirci, Fatih (Natural Products Inc, 2016)Thymoquinone (TQ) is one of the bioactive constituents of black cumin seed (Nigella sativa L.) oil. It is well known that this natural volatile quinone has remarkable antimicrobial effects, especially against Candida ... -
Antimicrobial activities of Ferulago essential oils
Demirci, Fatih; İşcan, Gökalp; Güven, Kıymet; Kırımer, Neşe; Demirci, Betül; Başer, K. Hüsnü Can (Verlag Z Naturforsch, 2000)Essential oils from Ferulago asparagifolia Boiss., F. galbanifera (Miller) W. Koch, F. humilis Boiss. (Endemic), F. trachycarpa Boiss. growing in Turkey were evaluated against 15 microorganisms for their antifungal and ... -
Antimicrobial activity of the essential oil of Centaurea aladagensis
Köse, Yavuz Bülent; İşcan, Gökalp; Demirci, Betül; Başer, K. Hüsnü Can; Çelik, S. (Elsevier Science BV, 2007)Composition of the water-distilled oil of the aerial parts of Centaurea aladagensis, endemic in Turkey, was analysed by GC-MS. Hexadecanoic acid (39.3%), caryophyllene oxide (6.6%) and hexahydrofamesyl acetone (4.3%) were ... -
Antimicrobial and Antioxidant Activities of Stachys lavandulifolia subsp lavandulifolia Essential Oil and its Infusion
İşcan, Gökalp; Demirci, Betül; Demirci, Fatih; Göğer, Fatih; Kırımer, Neşe; Köse, Yavuz Bülent; Başer, K. Hüsnü Can (Natural Products Inc, 2012)Stachys lavandulifolia Vahl. subsp. lavandulifolia (Lamiaceae) is widely used in south Anatolia as a herbal tea. It is used for the treatment of gastrointestinal and respiratory disorders. Constituents of the essential oil ... -
Antimicrobial and antioxidant activities of Stachys lavandulifolia subsp. lavandulifolia essential oil and its infusion
İşcan, Gökalp; Demirci, Betül; Demirci, Fatih; Göğer, Fatih; Kırımer, Neşe; Köse, Yavuz Bülent; Başer, K. Hüsnü Can (2012)Stachys lavandulifolia Vahl. subsp. lavandulifolia (Lamiaceae) is widely used in south Anatolia as a herbal tea. It is used for the treatment of gastrointestinal and respiratory disorders. Constituents of the essential oil ... -
Antimicrobial screening of Mentha piperita essential oils
İşcan, Gökalp; Kırımer, Neşe; Kürkçüoğlu, Mine; Başer, K. Hüsnü Can; Demirci, Fatih (American Chemical Society, 2002)Essential oils of peppermint Mentha piperita L. (Lamiaceae), which are used in flavors, fragrances, and pharmaceuticals, were investigated for their antimicrobial properties against 21 human and plant pathogenic microorganisms. ... -
The bioactive essential oil of Heracleum sphondylium L. subsp ternatum (Velen.) Brummitt
İşcan, Gökalp; Demirci, Fatih; Kürkçüoğlu, Mine; Kıvanç, Merih; Başer, K. Hüsnü Can (Walter De Gruyter GMBH, 2003)The essential oil of Heracleum sphondylium L. subsp. ternatum (Velen.) Brummit (Umbelliferae) was isolated from crushed seeds by means of hydrodistillation and analyzed by GC and GC/MS. Major components were identified as ... -
The bioactive essential oil of Heracleum sphondylium L. subsp. ternatum (Velen.) Brummitt
İşcan, Gökalp; Demirci, Fatih; Kürkçüoğlu, Mine; Kıvanç, Merih; Başer, K. Hüsnü Can (Verlag der Zeitschrift fur Naturforschung, 2003)The essential oil of Heracleum sphondylium L. subsp. ternatum (Velen.) Brummit (Umbelliferae) was isolated from crushed seeds by means of hydrodistillation and analyzed by GC and GC/MS. Major components were identified as ... -
Biological activity and composition of the essential oils of Achillea schischkinii Sosn. and Achillea aleppica DC. subsp aleppica
İşcan, Gökalp; Kırımer, Neşe; Kürkçüoğlu, Mine; Arabaci, T; Küpeli, E; Başer, K. Hüsnü Can (American Chemical Society, 2006)The essential Oils obtained by water distillation from aerial parts of Achillea schischkinii Sosn. and Achillea aleppica DC. subsp. aleppica were analyzed by gas chromatography and gas chromatography/mass spectrometry. ... -
Biotransformation of (-)-(R)-a-Phellandrene: Antimicrobial Activity of Its Major Metabolite
İşcan, Gökalp; Kırımer, Neşe; Demirci, Fatih; Demirci, Betül; Noma, Yoshiaki; Başer, K. Hüsnü Can (Wiley-V C H Verlag GMBH, 2012)Terpene derivatives converted by microbial biotransformation constitute an important resource for natural pharmaceutical, fragrance, and aroma substances. In the present study, the monoterpene a-phellandrene was biotransformed ... -
Chemical Composition and Biological Activity of Centaurea baseri: New Species from Turkey
Köse, Yavuz Bülent; İşcan, Gökalp; Göğer, Fatih; Akalın Çiftçi, Gülsen; Demirci, Betül; Başer, K. Hüsnü Can (Wiley-V C H Verlag GMBH, 2016)The genus Centaurea L. is one of the largest and important genera of Asteraceae family. Centaurea species have been widely used as herbal remedies in folk medicine for their antidandruff, antidiarrheic, antirheumatic, ... -
The essential oil constituents and antimicrobial activity of Anthemis aciphylla Boiss. var. discoidea Boiss
Başer, K. Hüsnü Can; Demirci, Betül; İşcan, Gökalp; Hashimoto, T.; Demirci, Fatih; Noma, Y.; Asakawa, Y. (2006)The essential oil of aerial parts, leaves and flowers of the endemic Anthemis aciphylla BOISS. var. discoidea BOISS. (Asteraceae) were obtained by hydrodistillation. The oils were analyzed both by GC and GC-MS on a polar ... -
The essential oil constituents and antimicrobial activity of Anthemis aciphylla Boiss. var. discoidea Boiss.
Başer, K. Hüsnü Can; Demirci, Betül; İşcan, Gökalp; Hashimoto, T; Demirci, Fatih; Noma, Y; Asakawa, Y (Pharmaceutical Soc Japan, 2006)The essential oil of aerial parts, leaves and flowers of the endemic Anthemis aciphylla BOISS. var. discoidea BOISS. (Asteraceae) were obtained by hydrodistillation. The oils were analyzed both by GC and GC-MS on a polar ... -
Preparation of some pyrazoline derivatives and evaluation of their antifungal activities
Özdemir, Ahmet; Turan, Gülhan; Kaplancıklı, Zafer Asım; Revıal, Gilbert; Demirci, Fatih; İşcan, Gökalp (Informa Healthcare, 2010)The synthesis of a new series of 1-[( benzazole-2-yl)thioacetyl]-3,5-diaryl-2-pyrazoline derivatives was obtained by reacting 1-( chloroacetyl)-3,5-diaryl-pyrazolines with 2-mercaptobenzimidazole/benzoxazole/benzothiazole. ... -
Studies on hydrazone derivatives as antifungal agents
Özdemir, Ahmet; Turan, Gülhan; Kaplancıklı, Zafer Asım; Demirci, Fatih; İşcan, Gökalp (Taylor & Francis LTD, 2008)The increasing clinical importance of drug-resistant fungal pathogens has urged additional need to fungal research and new antifungal compound development. For this purpose, some N-(1-benzyl-2-phenylethylidene)-N'-[4-(ar ... -
Synthesis and anticandidal activity of new triazolothiadiazine derivatives
Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım; Turan, Gülhan; Özdemir, Ahmet; İşcan, Gökalp; Akalın Çiftçi, Gülsen; Yıldırım, Şafak Ulusoylar (Elsevier France-Editions Scientifiques Medicales Elsevier, 2011)New triazolothiadiazine derivatives were synthesized via the ring closure reaction of 4-amino-5-substituted-2,4-dihydro-3H-1,2,4-triazol-3-thiones with phenacyl bromides. The compounds were tested in vitro against various ...