Kurum Yazarı "Arslan, Rana" PubMed İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Analgesic and antispasmodic activities of 2-(2-nitro-phenyl)-1 H-benzimidazole 5-carboxylic acid: Evidence for the importance of the 2-(o-substituted phenyl) group
Aydın, Süleyman; Arslan, Rana; Can, Özgür Devrim (2003)Benzimidazole 5-carboxylic acid derivatives were investigated for analgesic activity in this study. Of the benzimidazole compounds tested, 2-(2-nitro-phenyl)-1 H-benzimidazole 5-carboxylic acid showed remarkable naloxone ... -
Analgesic and antispasmodic activities of 2-(2-nitro-phenyl)-1H-benzimidazole 5-carboxylic acid: evidence for the importance of the 2-(o-substituted phenyl) group
Aydın, Süleyman; Arslan, Rana; Can, Özgür Devrim (Govi-Verlag GMBH, 2003)Benzimidazole 5-carboxylic acid derivatives were investigated for analgesic activity in this study. Of the benzimidazole compounds tested, 2-(2-nitro-phenyl)-1 H-benzimidazole 5-carboxylic acid showed remarkable naloxone ... -
Antinociceptive activity of methanol extract of fruits of Capparis ovata in mice
Arslan, Rana; Bektaş, Nurcan; Öztürk, Yusuf (Elsevier Ireland LTD, 2010)Ethnopharmacological relevance: Capparis ovata Desf. and Capparis spinosa L have wide natural distribution in Turkey and they are consumed in pickled form. Flower buds, root bark, and fruits of the plant are used in folk ... -
Antinociceptive effect of methanol extract of Capparis ovata in mice
Arslan, Rana; Bektaş, Nurcan (Taylor & Francis LTD, 2010)Context: Capparis ovata Desf. (Capparaceae) grows widely in Turkey. Flower buds and fruits of the plant are used in folk medicine for their analgesic, antirheumatismal, and diuretic effects. Objective:This study evaluated ... -
Antithrombotic effects of ethanol extract of Crataegus orientalis in the carrageenan-induced mice tail thrombosis model
Arslan, Rana; Bor, Zeynep; Bektaş, Nurcan; Meriçli, Ali Hikmet; Öztürk, Yusuf (Pergamon-Elsevier Science LTD, 2011)Introduction: Crataegus species (common name is Hawthorn) are medicinal plants, which have flavonoids, triterpene acids, proanthocyanidins, and organic acids as main constituents, used in the treatment of cardiovascular ... -
Chitosan gel formulations containing egg yolk oil and epidermal growth factor for dermal burn treatment
Yenilmez, Evrim; Başaran, E.; Arslan, Rana; Berkman, Murat Sami; Güven, Umay Merve; Baycu, C.; Yazan, Yasemin (Govi-Verlag Pharmazeutischer Verlag GMBH, 2015)In the present study chitosan based gel formulations containing Egg Yolk Oil (EYO) and Epidermal Growth Factor (EGF) were formulated successfully aiming at enhanced topical treatment of dermal burns the combination of ... -
Effects of Hypericum perforatum L and Hypericum calycinum L extracts on the central nervous system in mice
Öztürk, Yusuf; Aydın, Süleyman; Arslan, Rana; Başer, K. Hüsnü Can; Berberoğlu, H (Gustav Fischer Verlag, 1996)Hypericum species have been used as herbal remedies for the therapy of various diseases since ancient times. It has been reported that Hypericum perforatum is a useful herbal remedy for the treatment of neurological disorders ... -
Evaluation of the Antidiabetic Property of Capparis Ovata Desf. Var. Palaestina Zoh. Extracts Using In vivo and In vitro Approaches
Okur, Mehmet Evren; Polat, Derya C.; Özbek, Hanefi; Yılmaz, Sezen; Yoltas, Ayşegül; Arslan, Rana (Bentham Science Publ LTD, 2018)Background and Objective: This paper is focused on evaluating the various biological activities of C. ovata var. palaestina extracts which could beneficially influence diabetes and its complications. Methods: Alloxan-induced ... -
Evaluation of the antithrombotic effects of Crataegus monogyna and Crataegus davisii in the carrageenan-induced tail thrombosis model
Arslan, Rana; Bektaş, Nurcan; Bor, Zeynep; Şener, Erol (Informa Healthcare, 2015)Context: Crataegus species are widely used as herbal medicines for preventing cardiovascular diseases (CVDs). However, there are no studies on the effects of Crataegus monogyna Jacq. (Rosaceae) and C. davisii Browicz on ... -
The imidazoline receptors and ligands in pain modulations
Bektaş, Nurcan; Nemutlu, Dilara; Arslan, Rana (Wolters Kluwer Medknow Publications, 2015)Pain is an unpleasant experience and effects daily routine negatively. Although there are various drugs, many of them are not entirely successful in relieving pain, since pain modulation is a complex process involving ... -
Investigation for anti-inflammatory and anti-thrombotic activities of methanol extract of Capparis ovata buds and fruits
Bektaş, Nurcan; Arslan, Rana; Göğer, Fatih; Kırımer, Neşe; Öztürk, Yusuf (Elsevier Ireland LTD, 2012)Ethnopharmacological relevance: Capparis ovata Desf. has wide natural distribution in Turkey and it is consumed in pickled form. Flower buds, root bark, and fruits of the plant are used traditionally due to their analgesic, ... -
The involvement of endogenous opioid mechanisms in the antinociceptive effects induced by antidepressant drugs, desipramine and trimipramine
Öztürk, Yusuf; Aydın, Süleyman; Arslan, Rana; Herekman-Demir, Tuba (Pergamon-Elsevier Science LTD, 2006)The present study was designed to investigate the involvement of endogenous opioid systems in the antinociception induced by the antidepressant drugs, desipramine and trimipramine. For this purpose, the antinociceptive ... -
Nepetalactone: A new opioid analgesic from Nepeta caesarea Boiss.
Aydın, Süleyman; Arslan, Rana; Öztürk, Yusuf; Başer, K. Hüsnü Can (Royal Pharmaceutical Soc Great Britain, 1998)The essential oils of Nepeta species including Nepeta phyllochlamys P. H. Davis, N. nuda L. ssp. nude, and N. caesarea Boiss. have been screened by use of the tail-flick and tail immersion (52.5 degrees C) methods. Of the ... -
The possible mechanisms of protocatechuic acid-induced central analgesia
Arslan, Rana; Aydın, Şule; Samur, Dilara Nemutlu; Bektaş, Nurcan (Elsevier Science BV, 2018)It is aimed to investigate the central antinociceptive effect of protocatechuic acid and the involvement of stimulation of opioidergic, serotonin 5-HT2A/2C. alpha 2-adrenergic and muscarinic receptors in protocatechuic ... -
Preparation, characterization and pharmacokinetic evaluation of rosuvastatin calcium incorporated cyclodextrin-polyanhydride nanoparticles
Al-Heibshy, Fawaz N. S.; Başaran, Ebru; Arslan, Rana; Öztürk, Naile; Vural, İmran; Demirel, Müzeyyen (Taylor & Francis LTD, 2019)Objective: The aim of the study was to formulate, cyclodextrin (CD)-polyanhydride (PA) nanoparticles (CPNs) with rosuvastatin calcium (RCa) in order to enhance the poor oral bioavailability. Methods: CPNs containing RCa/CD ... -
Some pyrrole substituted aryl pyridazinone and phthalazinone derivatives and their antihypertensive activities
In this work, some 2-nonsubstituted/2-methyl-/2-(2-acetyloxyethyl)-6-[4- (substituted pyrrol-1-yl)phenyl]-4,5-dihydro-3(2H)-pyridazinone, derivatives and 2-nonsubstituted/2-methyl- 4-[4-(substituted pyrrol-1-yl)phenyl]-1(2H)- ... -
Synthesis and cytotoxic and analgesic activities of some 1, 5-diaryl-3-ethoxycarbonylpyrrole derivatives
Demirayak, Şeref; Arslan, Rana; Karaburun, Ahmet Çağrı; Kayagil, İsmail; Seller, Zerrin; Uçucu, Ümit (2006)Some 1,5-diaryl-3-ethoxycarbonyl-2-methylpyrrole derivatives were obtained by reacting 1-aryl-3-ethoxycarbonylpent-1,4-diones and a suitable aniline derivative or sulfanilamide under Paal-Knorr pyrrole synthesis conditions. ... -
Valnoctamide: The effect on relieving of neuropathic pain and possible mechanisms
Samur, Dilara Nemutlu; Arslan, Rana; Aydın, Şule; Bektaş, Nurcan (Elsevier Science BV, 2018)The purpose of this study is to assess the possible anti-allodynic and antihyperalgesic effect of valnoctamide, an amide derivative of valproic acid, at the doses of 40, 70 and 100 mg/kg (i.p.) in neuropathic pain model ... -
Zonisamide: Antihyperalgesic efficacy, the role of serotonergic receptors on efficacy in a rat model for painful diabetic neuropathy
Bektaş, Nurcan; Arslan, Rana; Öztürk, Yusuf (Pergamon-Elsevier Science LTD, 2014)Aims: The purpose of this study was to compare the changes of antihyperalgesic effectiveness of zonisamide (25 and 50 mg/kg), an antiepileptic drug, on the early and late phases of neuropathy and to investigate the role ...