Browsing PubMed İndeksli Yayınlar Koleksiyonu by Publisher "Elsevier"
Now showing items 1-10 of 10
-
4-Aminophenyl boronic acid modified gold platforms for influenza diagnosis
(Elsevier, 2013)As a potential pandemic threat to human health, there has been an urgent need for rapid, sensitive, simpler and less expensive detection method for the highly pathogenic influenza A virus. For this purpose, Quartz Crystal ... -
Benzenesulfonamide derivatives containing imine and amine groups: Inhibition on human paraoxonase and molecular docking studies
(Elsevier, 2020)Sulfonamides known as inhibitors of many metabolic enzymes have been widely used as antimicrobial drugs for a long time. in the present study, we investigated in vitro inhibitory activities of benzenesulfonamide derivatives ... -
Cytotoxicity of naturally occurring phenolics and terpenoids from Kenyan flora towards human carcinoma cells
(Elsevier, 2019)Background: Cancer constitutes a major hurdle worldwide and its treatment mainly relies on chemotherapy. Objectives: the present study was designed to evaluate the cytotoxicity of eleven naturally occurring compounds ... -
Determination of Ochratoxin-A in the brain microdialysates and plasma of awake, freely moving rats using ultra high performance liquid chromatography fluorescence detection method
(Elsevier, 2019)In this study, a simple, efficient and rapid Ultra High Performance Liquid Chromatography method with fluorescence detection (UHPLC-FLD) has been developed and validated for the determination of Ochratoxin-A (OTA) in rat ... -
Development of a RP-HPLC method for simultaneous determination of reference markers used for in-situ rat intestinal permeability studies
(Elsevier, 2020)One of the most common techniques for assessing the intestinal absorption characteristics of drugs is single-pass intestinal perfusion (SPIP) method. Metoprolol tartrate (MT, reference standard) and phenol red (PR, zero ... -
Evaluation of wound healing effect of chitosan-based gel formulation containing vitexin
(Elsevier, 2020)Acute or chronic wounds are one of the most common health problems worldwide and medicinal drugs or traditional remedies are often used in wound healing. Further studies regarding wound treatment are rapidly continuing. ... -
Identification of non-alkaloid natural compounds of Angelica purpurascens (Ave-Lall.) Gilli. (Apiaceae) with cholinesterase and carbonic anhydrase inhibition potential
(Elsevier, 2020)In current study is done antioxidant, anticholinesterase, and carbonic anhydrase isoenzymes I and II inhibition assays, screening of biological active compounds and electronic microscopy analysis of secretory canals of ... -
Inhibition effects of quinones on aldose reductase: Antidiabetic properties
(Elsevier, 2019)Diabetes mellitus is a chronic metabolic disease characterized by abnormal glucose metabolism. Aldose reductase (AR) is the first enzyme in the polyol pathway and converts glucose to sorbitol. It plays a vital role as a ... -
Physicochemical characterization and pharmacokinetic evaluation of rosuvastatin calcium incorporated solid lipid nanoparticles
(Elsevier, 2020)Rosuvastatin calcium (RCa) is a very efficient antihyperlipidemic agent, however, being a BCS class II drug, results in poor oral bioavailability. the present study focused on the enhancement of oral bioavailability of RCa ... -
The use of ecological footprint in estimating the Environmental Kuznets Curve hypothesis for BRICST by considering cross-section dependence and heterogeneity
(Elsevier, 2020)A vast body of literature estimates the impact of economic growth on environmental degradation in the framework of EKC model. Typical empirical studies proxy environmental degradation with CO2 emissions; however, this ...