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Toplam kayıt 13, listelenen: 1-10
Synthesis of New Hydrazone Derivatives for MAO Enzymes Inhibitory Activity
(MDPI, 2017)
In the present work, 14 new 1-substituted-2-phenylhydrazone derivatives were synthesized to evaluate their inhibitory activity against hMAO enzymes. The structures of the newly synthesized hydrazones 2a-2n were characterized ...
A Sensitive and Rapid Determination of Ranitidine in Human Plasma by HPLC with Fluorescence Detection and its Application for a Pharmacokinetic Study
(Oxford University Press Inc, 2012)
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Validated Method for the Determination of Piroxicam by Capillary Zone Electrophoresis and Its Application to Tablets
(Hindawi Publishing Corporation, 2014)
Simple and rapid capillary zone electrophoretic method was developed and validated in this study for the determination of piroxicam in tablets. The separation of piroxicam was conducted in a fused-silica capillary by using ...
Simple method of paroxetine determination using a single channel FIA with no in-line reaction process
(Japan Soc Analytical Chemistry, 2003)
A flow-injection analysis (FIA) of paroxetine hydrochloride (PRX), a selective serotonin reuptake inhibitor (SSRI) currently used as an antidepressant drug, is described. A 0.1 mol dm(-3) acetate buffer at pH 3.07 was found ...
Determination of Bupropion Using Liquid Chromatography with Fluorescence Detection in Pharmaceutical Preparations, Human Plasma and Human Urine
(Oxford University Press Inc, 2012)
A novel pre-column derivatization reversed-phase high-performance liquid chromatography with fluorescence detection is described for the determination of bupropion in pharmaceutical preparation, human plasma and human urine ...
Pharmacological and Toxicological Screening of Novel Benzimidazole-Morpholine Derivatives as Dual-Acting Inhibitors
(MDPI, 2017)
The aim of this study was to investigate acetylcholinesterase (AChE), monoamine oxidase A (MAO-A), monoamine oxidase B (MAO-B), cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzyme inhibitory, and antimicrobial ...
Development of Validated and Stability-Indicating LC-DAD and LC-MS/MS Methods for Determination of Avanafil in Pharmaceutical Preparations and Identification of a Novel Degradation Product by LCMS-IT-TOF
(MDPI, 2018)
Avanafil (AVA), one of the most effective drugs prescribed for erectile dysfunction, is a pyrimidine-derivative PDE5 inhibitor. In the current work, new LC methods were developed and validated for quantitative determination ...
Development of a validated high-performance liquid chromatographic method for the determination of Lurasidone in pharmaceuticals
(Marmara University, Fac Pharmacy, 2017)
A new, rapid and simple HPLC method for determination of Lurasidone in its tablets has been developed and validated. Lurasidone and internal standard (Chlorpromazine) was separated on a Zorbax XDB C8 column (4.6 x 50 mm, ...
A Stability Indicating Ion-Pair Lc Method for the Determination of Asenapine in Pharmaceuticals
(Soc Chilena Quimica, 2017)
In this study, a new, simple and specific stability indicating ion-pair LC method was developed and fully validated for the determination of asenapine in tablets. The analysis was performed on an Agilent Eclipse XDB-C8 ...
Synthesis, Molecular Docking Studies, and Antifungal Activity Evaluation of New Benzimidazole-Triazoles as Potential Lanosterol 14 alpha-Demethylase Inhibitors
(Hindawi LTD, 2017)
Due to anticandidal importance of azole compounds, a new series of benzimidazole-triazole derivatives(5a-5s) were designed and synthesized as ergosterol inhibitors. Thechemical structures of the target compounds were ...