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Toplam kayıt 15, listelenen: 1-10
Cytotoxic, Apoptotic and DNA Synthesis Inhibitory Effects of Some Thiazole Derivatives
(Bentham Science Publ LTD, 2017)
Background: Cancer is one of the leading causes of morbidity and mortality worldwide and extensive efforts have been devoted to the discovery of new anticancer agents. In the last few decades, the clinical efficacy of ...
Cytotoxic, Antiproliferative and Apoptotic Effects of Perillyl Alcohol and Its Biotransformation Metabolite on A549 and HepG2 Cancer Cell Lines
(Bentham Science Publ LTD, 2017)
Background: A monoterpene, perillyl alcohol, has attracted attention in medicinal chemistry since it exhibited chemo-preventive and therapeutic properties against a variety of cancers. Objective: In the present work, it ...
Novel morpholine dithiocarbamate derivatives induces apoptosis in C6 glioma
(Wiley-Blackwell, 2016)
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In vitro effects of alpha-tocopherol and ascorbic acid on antioxidant characteristics of HDL
(Turkish Biochem Soc, 2011)
Aim: High density lipoprotein (HDL) retards accumulation of proinflammatuar oxidized phospholipids in low density lipoproteins (LDL) and have a capacity on inhibition of oxidative modification. These antioxidant and ...
In vitro effects of ?-tocopherol and ascorbic acid on antioxidant characteristics of HDL [?-Tokoferol ve askorbik asitin HDL'nin antioksidan özelligi üzerine in vitro etkileri]
(2011)
phospholipids in low density lipoproteins (LDL) and have a capacity on inhibition of oxidative modification. These antioxidant and antiinflammatory properties are as important as its cholesterol efflux function on inhibition ...
Oxidative and inflammatory status and HDL functions of obese pre and post menopausal women
(Walter De Gruyter GMBH, 2014)
Objective: Obesity and age related vascular changes coupled with the effect of estrogen withdrawal increases predisposition to atherosclerosis in postmenopausal women. But the functions of high density lipoprotein (HDL) ...
Synthesis and biological evaluation of thiazoline derivatives as new antimicrobial and anticancer agents
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2014)
N'-(3,4-Diarylthiazol-2(3H)-ylidene)-2-(arylthio)acetohydrazides were synthesized and evaluated for their antimicrobial activity and cytotoxicity against NIH/3T3 cells. Compound 22 bearing 1-phenyl-1H-tetrazole and ...
The effects of atorvastatin on antioxidant/antiinflammatory properties of HDLs in hypercholesterolemics
(Tubitak Scientific & Technical Research Council Turkey, 2015)
Background/aim: Hypercholesterolemia is characterized by changes in lipid profile, nitric oxide pathway, and oxidative stress markers, but functions of high-density lipoprotein (HDL) were not well established in ...
A Comprehensive Study on Thiadiazole-Based Anticancer Agents Inducing Cell Cycle Arrest and Apoptosis/Necrosis Through Suppression of Akt Activity in Lung Adenocarcinoma and Glioma Cells
(Turkish Pharmacists Assoc, 2019)
Objectives: Akt is considered as an attractive target for anticancer drug discovery and development and therefore extensive efforts have been devoted to the discovery of new potent anticancer agents targeting Akt. Materials ...