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Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents
(Bentham Science Publ LTD, 2018)
Background: In medicinal chemistry, thiazoles have gained great importance in anti-fungal and anticancer drug design and development. Objectives: The aim of this study was to synthesize new quinoline-based thiazolyl hydrazone ...
Synthesis and Biological Evaluation of Some Hydrazone Derivatives as Anti-inflammatory Agents
(Bentham Science Publ LTD, 2012)
In the present study, some hydrazone derivatives were synthesized via the reaction of 3-cyclohexylpropionic acid hydrazide with various benzaldehydes. The chemical structures of the compounds were elucidated by spectroscopic ...
Synthesis and Antimicrobial Evaluation of Some 2,5-Disubstituted Benzimidazole Derivatives
(Bentham Science Publ LTD, 2013)
Some benzimidazole derivatives bearing hydrazone moiety were synthesized and their in vitro antimicrobial activity was determined against various gram-positive and gram-negative bacteria, and fungi using microbroth dilution ...
Synthesis of some hydrazone derivatives bearing purine moiety as anticancer agents [Antikanser ajanlar olarak pürin parçasi{dotless} taşi{dotless}yan bazi{dotless} hidrazon türevlerinin sentezi]
(Turkish Pharmacists Association, 2014)
In the present study, some hydrazone derivatives were synthesized via the reaction of 6-hydrazino-9-(ß-D-ribofuranosyl)-9H-purine with various benzaldehydes. The structures of the compounds were elucidated by spectroscopic ...
Synthesis and Evaluation of New Thiazole Derivatives as Potential Antimicrobial Agents
(Bentham Science Publ LTD, 2016)
In an effort to develop potent antimicrobial agents, new thiazolyl hydrazone derivatives were synthesized and investigated for their inhibitory effects on pathogenic bacteria and yeasts. MTT assay was carried out to determine ...
Synthesis and Evaluation of Tetrazole-Based Hydrazone Derivatives Bearing a Pyridine Moiety as Antimicrobial Agents
(Bentham Science Publ LTD, 2015)
2-[(1-Methyl/Phenyl-1H-tetrazol-5-yl)thio]-N'-[(aryl) methylidene/ethylidene] acetohydrazides were synthesized and investigated in vitro against pathogenic bacteria and Candida species for their antimicrobial activity using ...
Synthesis and Mosquitocidal Activity of a Series of Hydrazone Derivatives against Aedes aegypti
(Bentham Science Publ LTD, 2018)
Background: Aedes aegypti is an important mosquito vector for the transmission of several infectious diseases. Current insecticides play a vital role in controlling mosquitoes; however, the frequent use of insecticides has ...
Synthesis and Evaluation of New Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
(Bentham Science Publ LTD, 2017)
Background: In recent years, thiazole derivatives incorporated with hydrazone moiety have attracted a great deal of interest due to their pivotal role in the field of current cancer research. Methods: In the present study, ...
Synthesis and Biological Evaluation of New Pyrazole-based Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
(Bentham Science Publ LTD, 2014)
New pyrazole-based thiazolyl hydrazone derivatives were obtained via the ring closure reaction of 3,5-dimethyl-1H-1-phenylpyrazole-4-carboxaldehyde thiosemicarbazone with 2-bromoacetophenone derivatives. The compounds were ...
Synthesis of some novel hydrazone derivatives and evaluation of their antituberculosis activity [Bazi{dotless} yeni hidrazon türevlerinin sentezi ve bunlari{dotless}n antitüberküloz etkilerinin degerlendirilmesi]
(2010)
The heterocyclic hydrazone constitute an important class of biologically active drug molecules which have attractive attention of medicinal chemists due to their antituberculosis activities. For this purpose, new hydrazone ...