Mutagenic potential of water from the Tuz Lake, Turkey

Abstract

The mutagenic potential of water samples from the Tuz Lake, Turkey was examined by applying the Salmonella mutagenicity assay (Ames test), using TA 98 and TA 100 strains without metabolic activation. XAD 4 and XAD 16 column extracts of the samples were used in plate incorporation assay. The results obtained were negative for both TA 98 and TA 100, although the number of revertants of XAD 4 extracts at one station and XAD 16 extracts at another station were higher than those of the other stations for TA 100 strain, compared to the solvent control. The difference was not significant to be considered as mutagenic.