Eczacılık Fakültesi: Recent submissions
Now showing items 1-20 of 1731
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Combinatorial usage of Sumac Unriped Fruit Extract (Rhus Coriaria) and Tannic Acid enhanced synergistic anti-angiogenic effect on chick chorioallantoic membrane assay
(2021)Rhus coriaria (sumac) naturally grows worldwide and conta-ins many phytochemicals. Tannic acid is frequently used for treating medical conditions. The aim of this study is to de-termine the ... -
Purification of glutathione reductase from some tissues of Capoeta umblaand the inhibitory effects of some metal ions on enzyme activity
(2021)The aim of this study was to determine the in vitro inhibitory effects of some metal ions (silver ion (Ag+), cadmium ion (Cd2+), cobalt ion (Co2+), copper ion (Cu2+), nickel ion (Ni2+), lead ion (Pb2+) ... -
Design, synthesis and biological evaluation of new bis(thiosemicarbazone) derivatives as potential targeted anticancer agents for non-small cell lung cancer
(2020)Thiosemicarbazonesrepresent an important class of ligandsfortargeted therapyof many types of cancer including non-small celllung cancer. In order to identify potential antitumoragentsfor targeted therapy oflung cancer, new ... -
Dexketoprofen trometamol loaded solid lipid nanoparticles(SLNs): Formulation, in vitroand in vivoevaluation
(2020)Development, in vitroand in vivoevaluation of dexketoprofen trometamol (DT)-loaded nanosizeddrugdelivery system was aimed in this study. DT-loaded solid lipid nanoparticles (SLNs) were prepared using probe ... -
Biosorption of phenol and 2-chlorophenol by Funalia trogii pellets
(Elsevier Sci LTD, 2009)The removal of phenol (Ph) and 2-chlorophenol (2-CPh) from aqueous solution by native and heat inactivated fungus Funalia trogii pellets were investigated. The effects of contact time, solid/liquid ratio, optimum pH and ... -
Poly (hydroxyethyl methacrylate-glycidyl methacrylate) films modified with different functional groups: In vitro interactions with platelets and rat stem cells
(Elsevier Science BV, 2013)Copolymerization of 2-hydroxyethylmethactylate (HEMA) with glycidylmethacrylate (GMA) in the presence of alpha-alpha'-azoisobisbutyronitrile (AIBN) resulted in the formation of hydrogel films carrying reactive epoxy groups. ... -
Antibiotic susceptibility, antibacterial activity and characterisation of Enterococcus faecium strains isolated from breast milk
(Spandidos Publ LTD, 2016)Enterococci, which have useful biotechnological applications, produce bacteriocins, including those that exert anti-Listerial activity. The present study aimed to determine the antibiotic susceptibility patterns and ... -
Synthesis, antibacterial and antifungal activities of 3-(1,2,4-triazol-3-yl)-4-thiazolidinones
(Taylor & Francis LTD, 2009)A new series of 3-(1,2,4-triazol-3-yl)-4-thiazolidinone derivatives has been synthesized by the reaction of Schiff bases of 3-amino-1,2,4-triazoles with mercaptoacetic acid and 2-mercaptopropionic acid. Their antibacterial ... -
Antibacterial and antifungal activities of some trimethoprim salts
(Birkhauser Boston Inc, 2012)In this study, the antimicrobial activities of Trimethoprim (1), Trimethoprim + Maleic acid (2), Trimethoprim + Oxalic acid dihydrate (3), and Trimethoprim + trans-1,2-Cyclohexanedicarboxylic acid (4) were investigated for ... -
Synthesis, Characterization, Antibacterial, Antifungal and Antituberculous Activities of Some Macrocyclic Coordination Compounds of Zn(II), Cd(II) & Hg(II)
(Asian Journal Of Chemistry, 2011)The increasing clinical importance of drug-resistant mycobacterial pathogens has lent additional urgency to microbiological research and I new antimycobacterial compound development. For this purpose, in this study, Zn(II), ... -
Biosorption of Pb(II) From Aqueous Solutions by a Fungal Biomass in a Batch System: Equilibrium and Kinetic Studies
(Asian Journal Of Chemistry, 2009)In this study, the biosorption capacity of the fungus Sporotricum sp. biomass in removing of Pb(II) ions from aqueous solution were investigated with different parameters, such as pH, temperature and initial metal ion ... -
New Benzimidazole-1,2,4-Triazole Hybrid Compounds: Synthesis, Anticandidal Activity and Cytotoxicity Evaluation
(MDPI AG, 2017)Owing to the growing need for antifungal agents, we synthesized a new series 2-((5-(4-(5-substituted-1H-benzimidazol-2-yl)phenyl)-4-substituted-4H-1,2,4-triazol-3-yl)thio)-1-(substituted phenyl)ethan-1-one derivatives, ... -
New 1,4-dihydro[1,8]naphthyridine derivatives as DNA gyrase inhibitors
(Pergamon-Elsevier Science LTD, 2017)Owing to the growing need for novel antibacterial agents, we synthesized a novel series of fluoroquinolones including 7-substituted-1-(2,4-difluoropheny1)-6-fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid ... -
Design, synthesis, and evaluation of novel 2-phenylpropionic acid derivatives as dual COX inhibitory-antibacterial agents
(Taylor & Francis LTD, 2017)A series of 2-(4-substitutedmethylphenyl) propionic acid derivatives (6a-6m) were synthesized, characterized and evaluated for cyclooxygenase (COX) enzyme inhibitory and antimicrobial activity. Test compounds that exhibited ... -
Platinum(II)-azoimidazole drugs against TB and cancer: Structural studies, cytotoxicity and anti-mycobacterial activity
(Pergamon-Elsevier Science LTD, 2018)1-Alkyl-2-(arylazo)imidazoles (Haai-C4H9 (1), Haai-C10H21 (2)) and their Pt(II) complexes, [Pt(Haai-C4H9)Cl-2] (3) and [Pt(Haai-C10H21)Cl-2] (4) were synthesized and characterized by different spectroscopic studies and ... -
Synthesis of thiazole-phenylacetic acid compounds as dual antibacterial-COX enzymes inhibitors
(Çukurova University, Fac Medicine, 2017)Purpose: Present a new potential dual drug for patient suffering both inflammation and infection was aim of this study therefore investigation of anti-inflammatory and antimicrobial activity of new thiazole-phenylacetic ... -
A Ni(II) dinuclear complex bridged by end-on azide-N and phenolate-O atoms: spectral interpretation, magnetism and biological study
(Royal Soc Chemistry, 2015)A potential tetradentate monoanionic N2O2 chelator, HL, derived from the condensation of o-vanillin and N,N-dimethylethylenediammine, has been reacted with nickel perchlorate and sodium azide to yield the dinuclear Ni(II) ... -
Triply phenoxo bridged Eu(III) and Sm(III) complexes with 2,6-diformyl-4-methylphenol-di(benzoylhydrazone): structure, spectra and biological study in human cell lines
(Royal Soc Chemistry, 2015)Two dinuclear lanthanide(III) complexes, [M-2(HL)(3)] (M = Sm(III) (1), Eu(III) (2); H3L, 2,6-diformyl-4-methylphenol-di(benzoylhydrazone)) were generated with good yield and characterised systematically. The single crystal ...
